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Vaccine Design pp 241–249Cite as

Testing Novel Inactivation Methods and Adjuvants for Vaccines Against Streptococcus agalactiae in Nile Tilapia Oreochromis niloticus

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 2411))

Abstract

Inactivation by hydrogen peroxide and pH manipulation are two novel methods used recently in experimental vaccines against Streptococcus agalactiae in Nile tilapia. Here we describe in detail inactivation using novel methods as well as the classical method of inactivation. These vaccines showed similar moderate efficacy when compared to the conventional formaldehyde vaccine. In addition, we describe the inclusion of adjuvants in a hydrogen peroxide vaccine.

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Acknowledgments

This work was supported by the São Paulo Research Foundation (Fapesp)—Grant 2018/06137-1 and 2019/02339-1 and Scholarship 2016/18345-2, and the National Council for Scientific and Technological Development (CNPq)—Scholarship 141835/2018-4. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES) - Finance Code 001.

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Authors and Affiliations

  1. Aquaculture Center of Unesp (Caunesp), São Paulo State University (Unesp), Jaboticabal, SP, Brazil

    Fernando Carlos Ramos-Espinoza, Victor Alexander Cueva-Quiroz, Jefferson Yunis-Aguinaga, Norquis Caled Alvarez-Rubio, Nicoli Paganoti de Mello & Julieta Rodini Engrácia de Moraes

Authors
  1. Fernando Carlos Ramos-Espinoza
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  2. Victor Alexander Cueva-Quiroz
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  3. Jefferson Yunis-Aguinaga
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  4. Norquis Caled Alvarez-Rubio
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  5. Nicoli Paganoti de Mello
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  6. Julieta Rodini Engrácia de Moraes
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Corresponding author

Correspondence to Fernando Carlos Ramos-Espinoza .

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Editors and Affiliations

  1. Lankenau Institute for Medical Research, Wynnewood, PA, USA

    Sunil Thomas

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Ramos-Espinoza, F.C., Cueva-Quiroz, V.A., Yunis-Aguinaga, J., Alvarez-Rubio, N.C., de Mello, N.P., de Moraes, J.R.E. (2022). Testing Novel Inactivation Methods and Adjuvants for Vaccines Against Streptococcus agalactiae in Nile Tilapia Oreochromis niloticus. In: Thomas, S. (eds) Vaccine Design. Methods in Molecular Biology, vol 2411. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1888-2_14

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  • DOI: https://doi.org/10.1007/978-1-0716-1888-2_14

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1887-5

  • Online ISBN: 978-1-0716-1888-2

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