Abstract
Most of the studies performed on the control of oxidative phosphorylation deal with the control on the oxygen consumption flux. Nevertheless, a relevant flux for the cell is that of ATP production, since it is important for the homeostasis of the phosphate potential of the cell.
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References
J.P. Mazat, E. Jean-Bart, M. Rigoulet and B. Guérin, Control of oxydative phosphorylations in yeast mitochondria. Role of the phosphate carrier, Biochim. Biophys. Acta 849:7–15 (1985).
T. Letellier, M. Malgat and J.P. Mazat, Control of oxydative phosphorylation in rat muscle mitochondria. Applications to mitochondrial myopathies, Biochim. Biophys. Acta 1141: 58–64 (1993).
J.A. Morgan-Hughes, P. Darveniza, S.N. Kahn, D.N. Landon, R. M. Sherratt, J.M. Land and J.B. Clark, A mitochondrial myopathy characterized by a deficiency in reducible cytochrome b, Brain 100:617–640 (1977).
F.N. Gellerich, W.S. Kunz and R. Bohnensack, Estimation of flux control coefficients from inhibitor titrations by non-linear regression, FEBS Lett. 274:167–170 (1990).
H.G. Holzhütter and A. Colosimo, Simfit: A microcomputer software toolkit for modelistic studies in biochemistry, Comp. Appl. Biosci. 6:23–38 (1990).
J.J. Lemasters and C.R. Hackenbrock, Continuous measurement in mitochondrial suspensions by firefly luciferase luminescence, Biochem. Biophys. Res. Commun. 55:1262–1270 (1973).
J.J. Lemasters: Dynamic measurement of ATP with firefly luciferase bioluminescence, in: “Bioluminescence and Chemiluminescence: Basic Chemistry and Analytical Applications,” M.A. De Luca and W.D. McElroy, eds, Academic Press, New York, pp. 197–202 (1981).
R. Wibom, A Lundin and E. Hultman, A sensitive method for measuring ATP-formation in rat muscle mitochondria, Scand. J. Clin. Lab. Invest. 50:143–152 (1990).
A.P. Halestrap, The mitochondrial pyruvate carrier: Kinetics and specificity for substrates and inhibitors, Biochem. J. 148:85–96 (1975).
A.P. Halestrap and R.M. Denton, The specificity and metabolic implications of inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by a-cyano-4-hydroxycinnamate and related compounds, Biochem. J. 148:97–107 (1975).
A.K. Groen, R.J.A. Wanders, H.V. Westerhoff, R. van der Meer and J.M. Tager, Quantification of the contribution of various steps to the control of mitochondrial respiration, J. Biol. Chem. 257:2754–2757 (1982).
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© 1993 Springer Science+Business Media New York
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Jouaville, L., Ichas, F., Letellier, T., Malgat, M., Mazat, JP. (1993). Control of ATP Flux in Rat Muscle Mitochondria. In: Schuster, S., Rigoulet, M., Ouhabi, R., Mazat, JP. (eds) Modern Trends in Biothermokinetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2962-0_49
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DOI: https://doi.org/10.1007/978-1-4615-2962-0_49
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