Abstract
In this paper, we focus in an artificial mechanism to detain the beginning of the type-2 diabetes disease in those identified patients which might to be developing a phase of prediabetes. From purely electrical interactions or Coulomb forces between a deployed nano sensor around of beta cells and Calcium\(^{2+}\) ions, we propose an artificial entrance of Calcium ions inside the beta-cells allowing them to segregate insulin. The electrical interactions between positively charged insulin inside beta cells is the main assumption of this paper. The permanent segregation of insulin fits well inside of the architecture of advanced networks engineering that contemplates the usage of a bio cyber interface. Therefore, the artificial releasing of granules with repulsive electric forces of insulin becomes a manner to cheat beta cells. This might be also seen as an option to avoid the intake of prediabetes y diabetes pharmacology for large periods. Although the view of this work is theoretical and prospective, it is based entirely in closed-form physics equations that sustain the main claim of this paper: electric interactions driven by charged nano particles would be a window to stop the progress of diseases based on the induced or spontaneous deficit of proteins, hormones and cells that are crucially needed to maintain the human homeostasis.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
American Association of Clinical Endocrinologist: The American Association of Clinical Endocrinologists Medical Guidelines for the Management of Diabetes Mellitus: The AACE system of intensive diabetes self-management-2000 update. Endocr. Pract. 6(1), 43–84 (2000)
Kaarisalo, M.M., et al.: Diabetes worsens the outcome of acute ischemic stroke. Diab. Res. Clin. Pract. 69(3), 293–298 (2005)
Yoshida, M., et al.: Regulation of voltage-gated K+ channels by glucose metabolism in pancreatic beta-cells. FEBS Lett. 583(13), 2225–2230 (2009)
Nieto-Chaupis, H.: Nanodevices and the Internet of Bio-Nano Things for modifying insulin densities in pancreatic beta-cells through electrodynamics of Ca 2+. In: 2018 IEEE 13th Nanotechnology Materials and Devices Conference (NMDC), Portland (2018)
Jeon, H., et al.: Electrical force-based continuous cell lysis and sample separation techniques for development of integrated microfluidic cell analysis system: a review. Microelectron. Eng. 198, 55–72 (2018)
Pizarro-Delgado, J., et al.: KCI-permeabilized pancreatic Islets: an experimental model to explore the messenger role of ATP in the mechanism of insulin production. PLOS ONE 10(10), e0140096 (2015). https://doi.org/10.1371/journal.pone.0140096
Jackson, J.D.: Classical Electrodynamics, 3rd edn. Wiley, Hoboken (1999)
Nieto-Chaupis, H., Unluturk, B.D.: Can the nano level electrodynamics explain the very early diagnosis of diabetic nephropathy in type-2 diabetes patients? In: 2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) (2017)
Arslanagic, S., Ziolkowski, R.W.: Cylindrical and spherical active coated nanoparticles as nanoantennas: active nanoparticles as nanoantennas. IEEE Antennas Propag. Mag. 59(6), 14–29 (2017)
Nieto-Chaupis, H.: Evaluating the quality of service of the Internet of Bio-Nano Things in possible scenarios of applicability in the nanomedicine. In: 2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) (2017)
Balanis, C.A.: Antenna Theory: Analysis and Design, 4th edn. Wiley, Hoboken (2016)
Piro, G., Bia, P., Boggia, G., Caratelli, D., Grieco, L.A., Mescia, L.: Terahertz electromagnetic field propagation in human tissues: a study on communication capabilities. Nano Commun. Netw. 10, 51–59 (2016). ISSN 18787789
Gulbahar, B.: Theoretical analysis of magneto-inductive THz wireless communications and power transfer with multi-layer graphene nano-coils. IEEE Trans. Mol. Biol. Multi-scale Commun. 3, 60–70 (2017). ISSN 2372-2061
Nafari, M., Jornet, J.M.: Modeling and performance analysis of metallic plasmonic nano-antennas for wireless optical communication in nanonetworks. Access IEEE 5, 6389–6398 (2017). ISSN 2169-3536
Akyildiz, I.F., Jornet, J.M.: The Internet of Nano-Things. IEEE Wirel. Commun. 17(6), 58–63 (2010). ISSN 1536-1284
Akyildiz, I.F., Pierobon, M., Balasubramaniam, S., Koucheryavy, Y.: The Internet of Bio-Nano Things. IEEE Commun. Mag. 53(3), 32–40 (2015)
Jornet, J.M., Akyildiz, I.F.: The Internet of Multimedia Nano-Things in the Terahertz band. In: 18th European Wireless, Poznan, pp. 18–20, April 2012
Loscri, V., Vegni, A.M.: An acoustic communication technique of nanorobot swarms for nanomedicine applications. IEEE Trans. NanoBiosci. 14(6), 598–607 (2015)
Nieto-Chaupis, H.: Evaluating the quality of service of the Internet of Bio-Nano Things in possible scenarios of applicability in the nanomedicine. In: 2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) (2017)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering
About this paper
Cite this paper
Nieto-Chaupis, H. (2019). Cheating the Beta Cells to Delay the Beginning of Type-2 Diabetes Through Artificial Segregation of Insulin. In: Compagnoni, A., Casey, W., Cai, Y., Mishra, B. (eds) Bio-inspired Information and Communication Technologies. BICT 2019. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, vol 289. Springer, Cham. https://doi.org/10.1007/978-3-030-24202-2_1
Download citation
DOI: https://doi.org/10.1007/978-3-030-24202-2_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-24201-5
Online ISBN: 978-3-030-24202-2
eBook Packages: Computer ScienceComputer Science (R0)