Abstract
This article is intended to provide information about the development of a project, in order to assist the diagnosis of glaucoma through mathematical modeling of the human eye affected by increased Intraocular Pressure IOP. For this purpose a database was obtained from “Santa Lucía” Medical Clinic in Quito, Ecuador. This database is not only formed by the values of intraocular pressure, but also by the tests that detect damage to the optic nerve in the vision field, and as extra data, the value of the thickness of the cornea. This complements the IOP measurement, since, the greater the thickness, the smaller the pressure reading will be, and when it is thinner, the IOP tends to rise. the difference in corneal thickness according to the type of glaucoma where indicates the central corneal thickness is reduced in patients with normal-pressure glaucoma, suggesting that the IOP is underestimated in the presence of thin corneas, however, the specific finding of values paquimetry consistently lower in patients with normal IOP and glaucomatous damage involves the hypothesis that there may be a relationship between structural alterations (cribriform plate) patients with thin corneas and increased susceptibility to glaucoma progression. The mathematical modeling is divided into three equations which relate the increase in IOP with damage to the nerve fiber layer and with the decrease of the visual field.
Keywords
Preview
Unable to display preview. Download preview PDF.
References
Martins Joao C., Sousa Leonel A. “Bioelectronic Vision, Retinal Models, Evaluation Metrics and System Design”. Series on Bioengineering & Biomedical Engineering. Vol. 3. World Scientific, ISBN-13 978-981-279-430-7. 2009.
P. B. Martín, “Estudio de la Dinámica del humor acuoso mediante fluorofotometría en el glaucoma de ángulo abierto”, Departamento de Oftalmología, Facultad de Medicina, Universidad Complutense de Madrid, Madrid 2991
E. Aguilar R., S. Reyes G., “Glaucoma: La Enfermedad Silenciosa”, Centro optometría internacional, Junior 2006.
Tombran-Tink J., Barnstable C. J., Shields M. B. “Mechanisms of the Glaucoma, Disease Process and Therapeutic Modalities”. Ophthalmology Research. Human Press. ISBN: 978-1-58829-956-7. 2008
U.S. Department of Health and Human Services, ¨El Glaucoma¨, National Institutes of Health, National Eye Institute, NIH Publication No: 03-6515
Dr. D. Pérez, “Glaucoma”, Centro Universitario Oftalmológico Universidad Nacional de Tucumán, 2005.
Dr. Cesar Larrain Alzamora, capitulo 9 ‘’Glaucoma’’. Cirugia IV Oftalmologia. Obtenido el 10 de septiembre del 2014. Available: www.rinconmedico.com
Dr. Eugenio Maul de la Puente. “Glaucoma”. Escuela de Medicina Departamento de Oftalmologia Curso de Oftalmologia 2011. 5º año Medicina.
Prof. Dr. Juan R. Sampaolesi, ‘’Efecto Hipotensor de las Prostaglandinas versus la Asociación Fija Timolol-Dorzolamida en el perfil diario de presión intraocular en pacientes con glaucoma’’. Glaucoma Forum junio 2007.
Dr. Enrique Aramedía. “Glaucoma también conocido como neuropatía óptica glaucomatosa”. Policlinica Gipuzkoa. Servicio de oftalmología
SBG-Sociedad Boliviana de Glaucoma. “Tipos de Glaucoma”. Available: glaucomabolivia.com/tipos-de-glaucoma
Dr. Javier Fernando Casiraghi, dr. Juan Roberto Sampaolasi. Capítulo 9 ‘’Glaucoma’’. Carlos Agento-oftalmologia General-Introduccion para el especialista.
ACG-Asociacion Colombiana de Glaucoma. “Que es la curva de la presión ocular y como se realiza”. Available: www.glaucoma.org.co/curva%20de%20presion.html
La pérdida de la visión o también conocida como la agudeza visual. Reportaje. Blog de farmacia. Available: ec.globedia.com/perdida-vision-tambien-conocida-agudeza-visual.
David Carbonel Murillo. ‘’Aplicaciones clínicas de la paquimetría”. Grado en opyica y optometría universidad de Zaragoza. 2013.
SEAGIG. South East Asia Glaucoma Interest Group. Supported by ALLERGAN.”Gonioscopy”, Available: www.apglaucomasociety.org/toc/Gonioscopy(NM).pdf
Ferreras Antonio, “Glaucoma Imaging” Springer ISBN: 978-3-319-18958-1. DOI: 10.1007/978-3-319-18959-8, 2016.
National Eye Institute. Caption: Series of four photos demonstrating typical progression of vision loss due to glaucoma. Available: http://www.visionaware.org/info/your-eye-condition/glaucoma/patients-guide-to-living-with-glaucoma/125
Álvarez Rocío, Torres Sebastián, “Simulación y modelamiento del ojo humano como herramienta para la prevención del Glaucoma a través de la medición de la Presión Intraocular”. Universidad Politécnica Salesiana, 2015
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Pinos-Vélez, E., Alvarez-Cardenas, R., Torres-Ríos, S., Chacón, C.L., Ipanaqué-Alama, W., Serpa-Andrade, L. (2017). Mathematical Modeling of Human Eye Affected by Increased Intraocular Pressure as a tool for the Prevention of Glaucoma. In: Torres, I., Bustamante, J., Sierra, D. (eds) VII Latin American Congress on Biomedical Engineering CLAIB 2016, Bucaramanga, Santander, Colombia, October 26th -28th, 2016. IFMBE Proceedings, vol 60. Springer, Singapore. https://doi.org/10.1007/978-981-10-4086-3_143
Download citation
DOI: https://doi.org/10.1007/978-981-10-4086-3_143
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-4085-6
Online ISBN: 978-981-10-4086-3
eBook Packages: EngineeringEngineering (R0)