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Retrospective cohort study of laparoscopic ICG-Guided Lymphadenectomy in gastric cancer from a Western country center

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Abstract

Background

Indocyanine green (ICG) guided lymphadenectomy has been proposed has a technique to improve the lymphadenectomy of patients with gastric cancer. Nevertheless, experience with this procedure is scarce in Western countries.

Methods

A retrospective analytic study in a tertiary hospital in Spain was performed, comparing patients who underwent laparoscopic gastrectomy with (ICG cohort) and without (historic cohort) ICG guided lymphadenectomy.

Results

Thirty four patients were included (17 in each group). Although the number of positive nodes was similar in both groups (0.0 in the ICG cohort vs. 2 in the historic cohort, p = 0.119), the number of lymph nodes removed was higher in the ICG cohort (42.0 vs 28.0, p = 0.040). In the ICG cohort, more lymph nodes were positive for adenocarcinoma in the group of nodes that were positive for IGC (10.6% of the IGC + nodes vs. 1.9% in the ICG − nodes, p < 0.001).

Conclusions

ICG lymphadenectomy is a promising procedure that could improve the lymphadenectomy of patients with gastric cancer. ICG lymphadenectomy could be used to increase the number of lymph nodes removed in patients with a high-risk of nodal invasion or it could be used to reduce the surgical aggressiveness in fragile patients with a low-risk of nodal invasion.

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Authors and Affiliations

  1. Department of Surgery, Complejo Hospitalario Universitario de Vigo, C/Clara Campoamor 341, Vigo, Pontevedra, Spain

    Ignacio Maruri, María Hermelinda Pardellas, Oscar Cano-Valderrama, Patricia Jove, Marta López-Otero, Isabel Otero & Raquel Sánchez-Santos

  2. Instituto de Investigaciones Sanitarias Galicia Sur, Vigo, Spain

    Ignacio Maruri, María Hermelinda Pardellas, Oscar Cano-Valderrama, Patricia Jove, Marta López-Otero, Isabel Otero & Raquel Sánchez-Santos

  3. Department of Public Health, Complejo Hospitalario Universitario de Vigo, Vigo, Spain

    Victor Campo

  4. Department of Pathology, Complejo Hospitalario Universitario de Vigo, Vigo, Spain

    Rebeca Fernández

  5. Department of Gastroenterology, Complejo Hospitalario Universitario de Vigo, Vigo, Spain

    Nereida Fernández-Fernández

Authors
  1. Ignacio Maruri
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  2. María Hermelinda Pardellas
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Corresponding author

Correspondence to Oscar Cano-Valderrama.

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Disclosures

Ignacio Maruri, María Hermelinda Pardellas, Oscar Cano-Valderrama, Patricia Jove, Marta López-Otero, Isabel Otero, Victor Campo, Rebeca Fernández, Nereida Fernández-Fernández and Raquel Sánchez-Santos have no conflicts of interest or financial ties to disclose.

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Maruri, I., Pardellas, M.H., Cano-Valderrama, O. et al. Retrospective cohort study of laparoscopic ICG-Guided Lymphadenectomy in gastric cancer from a Western country center. Surg Endosc 36, 8164–8169 (2022). https://doi.org/10.1007/s00464-022-09258-y

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  • DOI: https://doi.org/10.1007/s00464-022-09258-y

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