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Efficacy of baths with mineral-medicinal water in patients with fibromyalgia: a randomized clinical trial

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Abstract

The layout of this study, designed as a randomized crossover clinical trial, is to evaluate the efficacy of an intervention with mineral-medicinal water from As Burgas (Ourense) in patients suffering from fibromyalgia. This sample was randomly divided into two groups: group A and group B. In phase 1, group A had 14 baths in thermal water for a month and standard pharmacological treatment; group B, standard pharmacological treatment. Washout period is 3 months. In phase 2, group A had standard treatment and group B had 14 baths in thermal water for a month plus standard treatment. The Fibromyalgia Impact Questionnaire (FIQ) was used; this grades the impact of the illness from 1 (minimum) to 10 (maximum), which was measured in both phases. Twenty-five patients were included in each group and the study was concluded with 20 patients in group A and 20 in group B. The intervention group obtained, once the baths finished, a mean score of 60.3 (± 11.8) and the control group of 70.8 (± 13.0) (p < 0.001). Three months later, the intervention group presented a mean score of 64.4 (± 10.6) and the control group of 5.0 (± 11.3) (p < 0.001). We can therefore conclude that the simple baths with mineral-medicinal water from As Burgas can make an improvement on the impact caused by fibromyalgia.

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References

  • Altan L, Bingöl U, Aykac M et al (2004) Investigation of the effects of pool-based exercise on fibromyalgia syndrome. Rheumatol Int 24:272–277

    Article  Google Scholar 

  • Ardıç F, Özgen M, Aybek H, Rota S, Çubukçu D, Gökgöz A (2007) Effects of balneotherapy on serum IL-1, PGE2 and LTB4 levels in fibromyalgia patients. Rheumatol Int 27:441–446

    Article  CAS  Google Scholar 

  • Arnold LM, Bennett RM, Crofford LJ, Dean LE, Clauw DJ, Goldenberg DL, Fitzcharles MA, Paiva ES, Staud R, Sarzi-Puttini P, Buskila D, Macfarlane GJ (2018) AAPT diagnostic criteria for fibromyalgia. J Pain. https://doi.org/10.1016/j.jpain.2018.10.008

  • Bağdatlı AO, Donmez A, Eröksüz R, Bahadır G, Turan M, Erdoğan N (2015) Does addition of ‘mud-pack and hot pool treatment’ to patient education make a difference in fibromyalgia patients? A randomized controlled single blind study. Int J Biometeorol 59:1905–1911

    Article  Google Scholar 

  • Baysal E, Leblebicioğlu H, Khorshid L, Sarı D (2018) Why individuals choose balneotherapy and benefit from this kind of treatment. Complement Ther Clin Pract 32:157–162

    Article  Google Scholar 

  • Bazzichi L, Da Valle Y, Rossi A, et al (2013) A multidisciplinary approach to study the effects of balneotherapy and mud-bath therapy treatments on fibromyalgia. Clin Exp Rheumatol 31:111–20

  • Branco M, Rego NN, Silva PH et al (2016) Bath thermal waters in the treatment of knee osteoarthritis: a randomized controlled clinical trial. Eur J Phys Rehabil Med 52:422–430

    Google Scholar 

  • Buskila D, Abu-Shakra M, Neumann L, Odes L, Shneider E, Flusser D, Sukenik S (2001) Balneotherapy for fibromyalgia at the Dead Sea. Rheumatol Int 20:105–108

    Article  CAS  Google Scholar 

  • Cassisi G, Sarzi-Puttini P, Casale R, Cazzola M, Boccassini L, Atzeni F, Stisi S (2014) Pain in fibromyalgia and related conditions. Reumatismo 66:72–86

    Article  CAS  Google Scholar 

  • Chandran AB, Coon CD, Martin SA, McLeod LD, Coles TM, Arnold LM (2012) Sphygmomanometry-evoked allodynia in chronic pain patients with and without fibromyalgia. Nurs Res 61:363–368. doi. https://doi.org/10.1097/NNR.0b013e318259b6cc

    Article  Google Scholar 

  • Dönmez A, Karagülle MZ, Tercan N, Dinler M, İşsever H, Karagülle M, Turan M (2005) SPA therapy in fibromyalgia: a randomised controlled clinic study. Rheumatol Int 26:168–172

    Article  Google Scholar 

  • Evcik D, Kızılay B, Gökçen E (2002) The effects of balneotherapy on fibromyalgia patients. Rheumatol Int 22:56–59

    Article  Google Scholar 

  • Fazaa A, Souabni L, Abdelghani KB, et al (2014) Comparison of the clinical effectiveness of thermal cure and rehabilitation in knee osteoarthritis. A randomized therapeutic trial. Ann Phys Rehabil Med 57:561–69

  • Fioravanti A, Perpignano G, Tirri G, Cardinale G, Gianniti C, Lanza CE, Loi A, Tirri E, Sfriso P, Cozzi F (2007) Effects of mud-bath treatment on fibromyalgia patients: a randomized clinical trial. Rheumatol Int 27:1157–1161

    Article  Google Scholar 

  • Fioravanti A, Cantarini L, Guidelli GM, Galeazzi M (2011) Mechanisms of action of spa therapies in rheumatic diseases: what scientific evidence is there? Rheumatol Int 31:1–8

    Article  Google Scholar 

  • Fioravanti A, Manica P, Bortolotti R, Cevenini G, Tenti S, Paolazzi G (2018) Is balneotherapy effective for fibromyalgia? Results from a 6-month double-blind randomized clinical trial. Clin Rheumatol 37:2203–2212

    Article  Google Scholar 

  • Forestier R, Erol-Forestier FB, Francon A (2017) Current role for spa therapy in rheumatology. Joint, Bone, Spine 84:9

    Article  Google Scholar 

  • Galvez I, Torres-Piles S, Ortega-Rincón E (2018) Balneotherapy, immune system and stress response: a hormetic strategy? Int J Mol Sci 19:1687

    Article  CAS  Google Scholar 

  • Guidelli G, Tenti S, De Nobili E et al (2012) Fibromyalgia syndrome and spa therapy: myth or reality? Clin Med Insights: Arthritis and Musculoskel Disord 5:19–26

    Google Scholar 

  • Häuser W, Jung E, Erbslöh-Möller B, Gesmann M, Kühn-Becker H, Petermann F, Langhorst J, Thoma R, Weiss T, Wolfe F, Winkelmann A (2012) The German fibromyalgia consumer reports–a cross-sectional survey. BMC Musculoskelet Disord 13:74

    Article  Google Scholar 

  • Karagülle M, Kardeş S, Karagülle MZ (2017) Real-life effectiveness of spa therapy in rheumatic and musculoskeletal diseases: a retrospective study of 819 patients. Int J Biometeorol 61:1945–1956

    Article  Google Scholar 

  • Koçyiğit BF, Gür A, Altındağ Ö et al (2016) Comparison of education and balneotherapy efficacy in patients with fibromyalgia syndrome: a randomized, controlled clinical study. Ağrı J Turkish Soc Algology 28:72–78

    Google Scholar 

  • Langhorst J, Musial F, Klose P, Hauser W (2009) Efficacy of hydrotherapy in fibromyalgia syndrome--a meta-analysis of randomized controlled clinical trials. Rheumatology (Oxford) 48:1155–1159

    Article  Google Scholar 

  • Macfarlane GJ, Kronisch C, Dean LE, Atzeni F, Häuser W, Fluß E, Choy E, Kosek E, Amris K, Branco J, Dincer F, Leino-Arjas P, Longley K, McCarthy GM, Makri S, Perrot S, Sarzi-Puttini P, Taylor A, Jones GT (2017) EULAR revised recommendations for the management of fibromyalgia. Ann Rheum Dis 76:318–328

    Article  CAS  Google Scholar 

  • Morer C, Roques CF, Françon A, Forestier R, Maraver F (2017) The role of mineral elements and other chemical compounds used in balneology: data from double-blind randomized clinical trials. Int J Biometeorol 61:2159–2173

    Article  Google Scholar 

  • Naumann J, Sadaghiani C (2014) Therapeutic benefit of balneotherapy and hydrotherapy in the management of fibromyalgia syndrome: a qualitative systematic review and meta-analysis of randomized controlled trials. Arthritis Res Ther 16:R141

    Article  Google Scholar 

  • Neumann L, Sukenik S, Bolotin A, Abu-Shakra M, Amir M, Flusser D, Buskila D (2001) The effect of balneotherapy at the Dead Sea on the quality of life of patients with fibromyalgia syndrome. Clin Rheumatol 20:15–19

    Article  CAS  Google Scholar 

  • Nugraha B, Neues-Lahusen M, Candir F, et al (2011) Wirkungen serieller H2S-Mineralwasserbäder auf Schmerzen bei Patienten mit Fibromyalgiesyndrom–eine Pilotstudie. Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin 21:284–89

  • Özkurt S, Dönmez A, Karagülle MZ et al (2012) Balneotherapy in fibromyalgia: a single blind randomized controlled clinical study. Rheumatol Int 32:1949–1954

    Article  Google Scholar 

  • Prandelli C, Parola C, Buizza L, Delbarba A, Marziano M, Salvi V, Zacchi V, Memo M, Sozzani S, Calza S, Uberti D, Bosisio D (2013) Sulphurous thermal water increases the release of the anti-inflammatory cytokine IL-10 and modulates antioxidant enzyme activity. Int J Immunopathol Pharmacol 26:633–646

    Article  CAS  Google Scholar 

  • Salgueiro M, García-Leiva JM, Ballesteros J, Hidalgo J, Molina R, Calandre EP (2013) Validation of a Spanish version of the revised fibromyalgia impact questionnaire (FIQR). Health Qual Life Outcomes 11:132

    Article  Google Scholar 

  • Theoharides TC, Tsilioni I, Arbetman L, Panagiotidou S, Stewart JM, Gleason RM, Russell IJ (2015) Fibromyalgia syndrome in need of effective treatments. J Pharmacol Exp Ther 355:255–263

    Article  CAS  Google Scholar 

  • Wolfe F, Clauw DJ, Fitzcharles M et al (2010) The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res 62:600–610

    Article  Google Scholar 

  • Wolfe F, Brähler E, Hinz A, Häuser W (2013) Fibromyalgia prevalence, somatic symptom reporting, and the dimensionality of polysymptomatic distress: results from a survey of the general population. Arthritis Care Res 65:777–785

    Article  Google Scholar 

  • Woodman I (2013) Fibromyalgia: fibromyalgia—all in the brain? Nat Rev Rheumatol 9:565

    Article  Google Scholar 

  • Yunus MB (2008) Central sensitivity syndromes: a new paradigm and group nosology for fibromyalgia and overlapping conditions, and the related issue of disease versus illness. Semin Arthritis Rheum 37:339–352

    Article  Google Scholar 

Download references

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Correspondence to María Reyes Pérez-Fernández.

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Pérez-Fernández, M.R., Calvo-Ayuso, N., Martínez-Reglero, C. et al. Efficacy of baths with mineral-medicinal water in patients with fibromyalgia: a randomized clinical trial. Int J Biometeorol 63, 1161–1170 (2019). https://doi.org/10.1007/s00484-019-01729-7

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  • DOI: https://doi.org/10.1007/s00484-019-01729-7

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