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Comparative biochemical, parasitological, and histopathological studies on cystic echinococcosis in infected sheep

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Abstract

Hydatid disease is a foremost public health and economic problem causing morbidity and mortality. This study was done to investigate the parasitological studies and biochemical and histopathological changes of hydatid cyst infection in livers of sheep. Our study was carried out prospectively on sheep slaughtered in a southern slaughterhouse, Hail city, conducted from January 2015 to December 2015 to determine the prevalence, cyst viability, and biochemical analysis of fertile and infertile hydatid fluids. Out of 53,981 slaughtered sheep, 3811 were found infected with hydatid cyst; specifically, hydatid cyst was detected in the liver of sheep. The overall infection rate in slaughtered sheep in this period (from 1 January 2015 to 30 December 2015) was 7.06%. The fertility rate of 330 examined hydatid cysts selected from the overall slaughtered sheep was observed to be 18.18%. Hydatid cyst fluid collected from fertile cyst had high levels of calcium, phosphorus, potassium, chloride, iron, and alkaline phosphatase activity but a low level of sodium, glucose, cholesterol, triglycerides, and total protein as compared to infertile hydatid fluid. Sections from infected liver showed distinct hydatid cyst structures and fibrous tissue; also, hepatic tissue showed necrosis of variable degrees. The prevalence of cystic Echinococcus in Hail area was at an overall rate of 7.06% and the majority of cysts in sheep were infertile. Additionally, biochemical analysis of HF could be helpful for the diagnosis of hepatic hydatid cysts which have a deleterious effect on morbidity and mortality in sheep.

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Authors and Affiliations

  1. Department of Biochemistry, College of Medicine, Hail University, Hail, Kingdom of Saudi Arabia

    Nabil A. Hasona

  2. Faculty of Science, Chemistry Department, Beni-Suef University, Beni-Suef, Egypt

    Nabil A. Hasona

  3. Department of Clinical Laboratory Science, College of Applied Medical Sciences, Hail University, Hail, Kingdom of Saudi Arabia

    Omar H. Amer & Abdullah Morsi

  4. Department of Parasitology, Animal Health Reaserch Instituate, Zagazig, Egypt

    Azza Raef

Authors
  1. Nabil A. Hasona
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  2. Omar H. Amer
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  3. Abdullah Morsi
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  4. Azza Raef
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All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. The study protocol was approved by the Animal Ethics Committee in the College of medicine, Hail University.

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The authors declare that they have no conflict of interest.

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The authors declare that they have received no funding for the research reported.

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Hasona, N.A., Amer, O.H., Morsi, A. et al. Comparative biochemical, parasitological, and histopathological studies on cystic echinococcosis in infected sheep. Comp Clin Pathol 26, 805–810 (2017). https://doi.org/10.1007/s00580-017-2450-2

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  • DOI: https://doi.org/10.1007/s00580-017-2450-2

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