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Serious fungal infections in Peru

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Abstract

Epidemiological data about mycotic diseases are limited in Peru and estimation of the fungal burden has not been previously attempted. Data were obtained from the Peruvian National Institute of Statistics and Informatics, UNAIDS and from the Ministry of Health’s publications. We also searched the bibliography for Peruvian data on mycotic diseases, asthma, COPD, cancer and transplants. Incidence or prevalence for each fungal disease were estimated in specific populations at risk. The Peruvian population for 2015 was 31,151,543. In 2014, the estimated number of HIV/AIDS and pulmonary tuberculosis cases was 88,625, 38,581 of them not on ART, and 22,027, respectively. A total of 581,174 cases of fungal diseases were estimated, representing approximately 1.9% of the Peruvian population. This figure includes 498,606, 17,361 and 4,431 vulvovaginal, oral and esophageal candidiasis, respectively, 1,557 candidemia cases, 3,593 CPA, 1,621 invasive aspergillosis, 22,453 allergic bronchopulmonary aspergilllosis, 29,638 severe asthma with fungal sensitization, and 1,447 Pneumocystis pneumonia. This first attempt to assess the fungal burden in Peru needs to be refined. We believe the figure obtained is an underestimation, because of under diagnosis, non-mandatory reporting and lack of a surveillance system and of good data about the size of populations at risk.

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Authors and Affiliations

  1. Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, San Martin de Porres, Lima 31, Lima, Peru

    B. Bustamante

  2. The University of Manchester and The National Aspergillosis Centre, University Hospital of South Manchester in association with the LIFE program at www.LIFE-Worldwide.org, Manchester, UK

    D. W. Denning

  3. Investigaciones Medicas en Salud, Calle Riso 390, 4to piso, Lince, Lima14, Lima, Peru

    P. E. Campos

Authors
  1. B. Bustamante
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  3. P. E. Campos
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Corresponding author

Correspondence to B. Bustamante.

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Potential conflicts of interest

Dr. Beatriz Bustamante currently receives funding for research from Merck Sharp & Dohme Corp (Merck Investigators Studies Program).

Dr. David W. Denning holds Founder shares in F2G Ltd a University of Manchester spin-out antifungal discovery company, in Novocyt which markets the Myconostica real-time molecular assays and has current grant support from the National Institute of Health Research, Medical Research Council, Global Action Fund for Fungal Infections and the Fungal Infection Trust. He acts or has recently acted as a consultant to Astellas, Sigma Tau, Basilea, Scynexis, Cidara and Pulmocide. In the last 3 years, he has been paid for talks on behalf of Astellas, Dynamiker, Gilead, Merck and Pfizer. He is also a member of the Infectious Disease Society of America Aspergillosis Guidelines and European Society for Clinical Microbiology and Infectious Diseases Aspergillosis Guidelines groups.

Dr. Pablo E. Campos currently receives funding to conduct clinical trials from Bristol-Myers Squibb Peru and from Merck Sharp & Dohme Peru.

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Bustamante, B., Denning, D.W. & Campos, P.E. Serious fungal infections in Peru. Eur J Clin Microbiol Infect Dis 36, 943–948 (2017). https://doi.org/10.1007/s10096-017-2924-9

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  • DOI: https://doi.org/10.1007/s10096-017-2924-9

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