Abstract
The chemistry laboratory at the Peruvian Institute of Nuclear Energy (IPEN) has carried out a validation method for the samples of siliceous composition. At least seven variables affecting the robustness of the results were initially identified, which may interact simultaneously or individually. Conventional evaluation hereof would imply a massive number of analyses and a far more effective approach for assessment of the robustness for these effects was found in the Youden-Steiner test, which provides the necessary information by only eight analyses for each sample type. Three reference materials were used for evaluating the effects of variations in sample mass, irradiation duration, standard mass, neutron flux, decay time, counting time and counting distance.
Similar content being viewed by others
References
ISO/IEC 17025:2005, General Requirements for the Competence of Testing and Calibration Laboratories, 2005.
EURACHEM Guide, The Fitness for Purpose of Analytical Methods. A Laboratory Guide to Method Validation and Related Topic, 1998.
W. J. Youden, E. H. Steiner, Statistical Manual of the Association of Official Analytical Chemist, AOAC International, USA, 1998, p. 33.
W. J. Youden, E. H. Steiner, Statistical Manual of the Association of Official Analytical Chemist, AOAC International, USA, 1998, p. 70; 82.
M. Catro, S. S. Gascon, Validación de métodos analíticos. Sección Catalana de A.E.F.I. Comisión de normas de buena fabricación y control de la calidad, Sept, 1989. p. 1.
E. H. Montoya, I. M. Cohen, P. Mendoza, B. Torres, P. Bedregal, J. Radioanal. Nucl. Chem., 240 (1999) 475.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bedregal, P., Torres, B., Ubillús, M. et al. Robustness in NAA evaluated by the Youden and Steiner test. J Radioanal Nucl Chem 278, 801–806 (2008). https://doi.org/10.1007/s10967-008-1704-5
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10967-008-1704-5