Abstract
In 2019, worldwide cultivation of herbicide-resistant crops covered 166.6 million hectares and 88% of the global genetically modified (GM) crop area. Since the introduction of soybeans that are resistant to the herbicide glyphosate, a 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase inhibitors, many farmers have repeatedly used the glyphosate herbicide in crops such as corn, cotton, and rice, and weeds have now been found to resist it. The appearance of weeds, resistant to EPSP synthase (EPSPS) inhibitors, acetolactate synthase (ALS), synthetic auxins, and photosystem II(PSII) inhibitors, have caused farming difficulties. Therefore, we have taken a genetic approach to herbicide resistance as a developing method in these GM crops. Patients from five major countries, including the United States of America (US), China (CN), Europe (EP), Japan (JP), and Korea (KR), with the World Intellectual Property Organization (WIPO) are being searched, the trend on the herbicide resistance transgenes including EPSPS, glyphosate oxidase (GOX), glyphosate-N-acetyltransferase (GAT), glyphosate decarboxylase, phosphinothricin acetyltransferase (PAT), dicamba monooxygenase (DMO), aryloxyalkanoate dioxygenase (AAD), 2,4-D monooxygenase, acetolactate synthase (ALS), acetohydroxyacid synthase (AHAS), photosystem II protein D1, cytochrome P450, hydroxyphenylpyruvate dioxygenase (HPPD), bromoxynil nitrylase (BXN) and applied crops including soybean, canola, cotton, corn, wheat, carnation, rice, tobacco, tomato are analyzed separately. Multinational conglomerates such as Monsanto, Dow, BASF and Bayer are concentrating and maintaining their influence on the development of soybean and corn using genes such as EPSPS, AHAS and HPPD. Therefore, in the case of other developers, it would be better to develop other crops to which other genes such as P450, BOX, and D1 are applied.
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References
Arregui MC, Lenardón A, Sanchez D, Maitre MI, Scotta R, Enrique S (2004) Monitoring glyphosate residues in transgenic glyphosate-resistant soybean. Pest Manage Sci 60:163–166
Baek Y, Bobadilla LK, Giacomini DA, Montgomery JS, Murphy BP, Tranel PJ (2021) Evolution of glyphosate-resistant weeds. Rev Environ Contam Toxicol 255:93–128
DeBlock M (1990) Factors influencing the tissue culture and the Agrobacterium tumefaciens-mediated transformation of hybrid aspen and popular clones. Plant Physiol 93:1110–1106
Duke SO (2005) Taking stock of herbicide-resistant crops ten year after introduction. Pest Manag Sci 61:211–218
Fartyal D, Agarwal A, James D, Borphukan B, Ram B, Sheri V, Agrawal PK, Achary VMM, Reddy MK (2018) Developing dual herbicide tolerant transgenic rice plants for sustainable weed management. Sci Rep 8:11598
Gianessi L (2005) Economic and herbicide use impacts of glyphosate-resistant crops. Pest Manag Sci 61(3):241–245
Gianessi LP (2013) The increasing importance of herbicides in worldwide crop production. Pest Manag Sci 69:1099–1105
Gray E, Call NM (1993) Fertilization and mowing on persistence of Indian mockstrawberry (Duchesnea indica) and common blue violet (Viola papilionaceae) in tall fescue (Festuca arundinacea) lawn. Weed Sci 41:548–550
Green JM (2012) The benefits of herbicide-resistant crops. Pest Manag Sci 68(10):1323–1331
Green JM, Siehl DL (2021) History and outlook for glyphosate-resistant crops. Rev Environ Contam Toxicol 255:67–91
Han SS, Jeong JH, Bang KS, Yang DC (1997) Selection of herbicide resistant potatoes transformed with phosphinothricin acetyltransferase gene. Kor J Weed Sci 17:373–382
Han Y, Kim J (2019) Application of CRISPR/Cas9-mediated gene editing for the development of herbicide-resistant plants. Plant Biotechnol Rep 13:447–457
Heap I (2022) The international herbicide-resistant weed database. Available at www.weedscience.co
Hérouet C, Esdaile DJ, Mallyon BA, Debruyne E, Schulz A, Currier T, Hendrickx K, van der Klis RJ, Rouan D (2005) Safety evaluation of the phosphinothricin acetyltransferase proteins encoded by the pat and bar sequences that confer tolerance to glufosinate-ammonium herbicide in transgenic plants. Regul Toxicol Pharmacol 41:134–149
ISAAA (2019) Global status of commercialized Biotech/GM crops in 2019: Biotech crops drive socioeconomic development and sustainable environment in the new frontier. ISAAA Brief No. 55. ISAAA: Ithaca, NY.
Jeong H (2020) Characterization of transgenic zoysiagrass with overexpression of AT-hook motif nuclear-localized (AHL) and protoporphyrinogen oxidase (PROTOX), and molecular biological characteristics for practical use of event Jeju Green 21-MJ3, Ph.D thesis
Owen MDK, Zelaya IA (2005) Herbicide-resistant crops and weed resistance to herbicides. Pest Manag Sci 61:301–311
Russnogle J (1998) Roundup ready soybean system simply works. Soybean Digest 1998:30–31
Sandermann H (2006) Plant biotechnology: ecological case studies on herbicide resistance. Trends Plant Sci 11:324–328
Takano HK, Dayan FE (2020) Glufosinate-ammonium: a review of the current state of knowledge. Pest Manag Sci 76:3911–3925
Uslu T (2021) Advantages, risks and legal perspectives of GMOs in 2020s. Plant Biotechnol Rep 15:741–751
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This research was supported by the 2022 scientific promotion program funded by Jeju National University.
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Jeju National University, 2022, In-Jung Kim.
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Kim, B., Kim, IJ. Worldwide patent trend analysis of herbicide-resistant genes. Plant Biotechnol Rep 16, 509–518 (2022). https://doi.org/10.1007/s11816-022-00783-9
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DOI: https://doi.org/10.1007/s11816-022-00783-9