Skip to main content
SpringerLink
Log in

Worldwide patent trend analysis of herbicide-resistant genes

  • Review
  • Published:
Plant Biotechnology Reports Aims and scope Submit manuscript

Abstract

In 2019, worldwide cultivation of herbicide-resistant crops covered 166.6 million hectares and 88% of the global genetically modified (GM) crop area. Since the introduction of soybeans that are resistant to the herbicide glyphosate, a 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase inhibitors, many farmers have repeatedly used the glyphosate herbicide in crops such as corn, cotton, and rice, and weeds have now been found to resist it. The appearance of weeds, resistant to EPSP synthase (EPSPS) inhibitors, acetolactate synthase (ALS), synthetic auxins, and photosystem II(PSII) inhibitors, have caused farming difficulties. Therefore, we have taken a genetic approach to herbicide resistance as a developing method in these GM crops. Patients from five major countries, including the United States of America (US), China (CN), Europe (EP), Japan (JP), and Korea (KR), with the World Intellectual Property Organization (WIPO) are being searched, the trend on the herbicide resistance transgenes including EPSPS, glyphosate oxidase (GOX), glyphosate-N-acetyltransferase (GAT), glyphosate decarboxylase, phosphinothricin acetyltransferase (PAT), dicamba monooxygenase (DMO), aryloxyalkanoate dioxygenase (AAD), 2,4-D monooxygenase, acetolactate synthase (ALS), acetohydroxyacid synthase (AHAS), photosystem II protein D1, cytochrome P450, hydroxyphenylpyruvate dioxygenase (HPPD), bromoxynil nitrylase (BXN) and applied crops including soybean, canola, cotton, corn, wheat, carnation, rice, tobacco, tomato are analyzed separately. Multinational conglomerates such as Monsanto, Dow, BASF and Bayer are concentrating and maintaining their influence on the development of soybean and corn using genes such as EPSPS, AHAS and HPPD. Therefore, in the case of other developers, it would be better to develop other crops to which other genes such as P450, BOX, and D1 are applied.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

References

  • Arregui MC, Lenardón A, Sanchez D, Maitre MI, Scotta R, Enrique S (2004) Monitoring glyphosate residues in transgenic glyphosate-resistant soybean. Pest Manage Sci 60:163–166

    Article  CAS  Google Scholar 

  • Baek Y, Bobadilla LK, Giacomini DA, Montgomery JS, Murphy BP, Tranel PJ (2021) Evolution of glyphosate-resistant weeds. Rev Environ Contam Toxicol 255:93–128

    PubMed  Google Scholar 

  • DeBlock M (1990) Factors influencing the tissue culture and the Agrobacterium tumefaciens-mediated transformation of hybrid aspen and popular clones. Plant Physiol 93:1110–1106

    Article  CAS  Google Scholar 

  • Duke SO (2005) Taking stock of herbicide-resistant crops ten year after introduction. Pest Manag Sci 61:211–218

    Article  CAS  Google Scholar 

  • Fartyal D, Agarwal A, James D, Borphukan B, Ram B, Sheri V, Agrawal PK, Achary VMM, Reddy MK (2018) Developing dual herbicide tolerant transgenic rice plants for sustainable weed management. Sci Rep 8:11598

    Article  CAS  Google Scholar 

  • Gianessi L (2005) Economic and herbicide use impacts of glyphosate-resistant crops. Pest Manag Sci 61(3):241–245

    Article  CAS  Google Scholar 

  • Gianessi LP (2013) The increasing importance of herbicides in worldwide crop production. Pest Manag Sci 69:1099–1105

    Article  CAS  Google Scholar 

  • Gray E, Call NM (1993) Fertilization and mowing on persistence of Indian mockstrawberry (Duchesnea indica) and common blue violet (Viola papilionaceae) in tall fescue (Festuca arundinacea) lawn. Weed Sci 41:548–550

    Article  Google Scholar 

  • Green JM (2012) The benefits of herbicide-resistant crops. Pest Manag Sci 68(10):1323–1331

    Article  CAS  Google Scholar 

  • Green JM, Siehl DL (2021) History and outlook for glyphosate-resistant crops. Rev Environ Contam Toxicol 255:67–91

    PubMed  Google Scholar 

  • Han SS, Jeong JH, Bang KS, Yang DC (1997) Selection of herbicide resistant potatoes transformed with phosphinothricin acetyltransferase gene. Kor J Weed Sci 17:373–382

    Google Scholar 

  • Han Y, Kim J (2019) Application of CRISPR/Cas9-mediated gene editing for the development of herbicide-resistant plants. Plant Biotechnol Rep 13:447–457

    Article  Google Scholar 

  • Heap I (2022) The international herbicide-resistant weed database. Available at www.weedscience.co

  • Hérouet C, Esdaile DJ, Mallyon BA, Debruyne E, Schulz A, Currier T, Hendrickx K, van der Klis RJ, Rouan D (2005) Safety evaluation of the phosphinothricin acetyltransferase proteins encoded by the pat and bar sequences that confer tolerance to glufosinate-ammonium herbicide in transgenic plants. Regul Toxicol Pharmacol 41:134–149

    Article  CAS  Google Scholar 

  • ISAAA (2019) Global status of commercialized Biotech/GM crops in 2019: Biotech crops drive socioeconomic development and sustainable environment in the new frontier. ISAAA Brief No. 55. ISAAA: Ithaca, NY.

  • Jeong H (2020) Characterization of transgenic zoysiagrass with overexpression of AT-hook motif nuclear-localized (AHL) and protoporphyrinogen oxidase (PROTOX), and molecular biological characteristics for practical use of event Jeju Green 21-MJ3, Ph.D thesis

  • Owen MDK, Zelaya IA (2005) Herbicide-resistant crops and weed resistance to herbicides. Pest Manag Sci 61:301–311

    Article  CAS  Google Scholar 

  • Russnogle J (1998) Roundup ready soybean system simply works. Soybean Digest 1998:30–31

    Google Scholar 

  • Sandermann H (2006) Plant biotechnology: ecological case studies on herbicide resistance. Trends Plant Sci 11:324–328

    Article  CAS  Google Scholar 

  • Takano HK, Dayan FE (2020) Glufosinate-ammonium: a review of the current state of knowledge. Pest Manag Sci 76:3911–3925

    Article  CAS  Google Scholar 

  • Uslu T (2021) Advantages, risks and legal perspectives of GMOs in 2020s. Plant Biotechnol Rep 15:741–751

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This research was supported by the 2022 scientific promotion program funded by Jeju National University.

Funding

Jeju National University, 2022, In-Jung Kim.

Author information

Authors and Affiliations

  1. Intellectual Property Education Center, Jeju National University, Jeju, 63243, Korea

    Beom Yong Kim & In-Jung Kim

  2. Faculty of Biotechnology, College of Applied Life Sciences, Jeju National University, Jeju, 63243, Korea

    In-Jung Kim

  3. Research Institute for Subtropical Agriculture and Biotechnology, Subtropical Horticulture Research Institute, Bio‐Resources Computing Research Center, SARI, Jeju National University, Jeju, 63243, Korea

    In-Jung Kim

Authors
  1. Beom Yong Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. In-Jung Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to In-Jung Kim.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 33 KB)

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, B., Kim, IJ. Worldwide patent trend analysis of herbicide-resistant genes. Plant Biotechnol Rep 16, 509–518 (2022). https://doi.org/10.1007/s11816-022-00783-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11816-022-00783-9

Keywords

Search

Navigation