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Spanish Society of Radiation Oncology clinical guidelines for stereotactic body radiation therapy in lymph node oligometastases

  • Clinical Guides in Oncology
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Abstract

Data in the literature support the existence of a state of limited metastases or oligometastases. Favorable outcomes have been observed in selected patients with such oligometastases that are treated with local ablative therapies, which include surgical extirpation, stereotactic body radiation therapy (SBRT), and radiofrequency ablation. The role of SBRT in the setting of lymph node oligometastases is still emerging but the early results for local control are promising. However, the biggest challenge is to identify patients who will benefit from treatment of their oligometastatic disease with local aggressive therapy. Patients are initially categorized based upon examination of the initial biopsy, location, stage, and previous treatments received. Appropriate patient management with SBRT requires an understanding of several clinicopathological features that help to identify several subsets of patients with more responsive tumors and a good tolerance to SBRT. In an effort to incorporate the most recent evidence, here the Spanish Society of Radiation Oncology presents guidelines for using SBRT in lymph node oligometastases.

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Acknowledgments

The authors wish to thank the Provincial Hospital of Castellón Foundation for their assistance in the development of this manuscript.

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Authors and Affiliations

  1. Radiation Oncology, Hospital Provincial de Castellon, Dr. Clara n 19 Ave, Castellon, Spain

    A. J. Conde-Moreno

  2. Radiation Oncology, University Hospital Virgen del Rocio, Manuel Siurot Ave s/n, 41013, Seville, Spain

    J. L. Lopez-Guerra

  3. Radiation Oncology, Salamanca University Hospital, Paseo de San Vicente, Salamanca, Spain

    V. A. Macias

  4. Unidad de Oncología Radioterápica, Hospital Meixoeiro-Galaria, Vigo, Hospital Meixoeiro, C/Meixoeiro sn, 36300, Pontevedra, Spain

    M. L. Vázquez de la Torre

  5. Oncología Radioterapica, Hospital Universitario Rey Juan Carlos, C/ Gladiolo s/n, Mostoles, Spain

    P. Samper Ots

  6. Radiation Oncology, Hospital Quirón Barcelona and Hospital Universitari Quirón Dexeus, Plaza de Alfonso Comín, 5, Barcelona, Spain

    S. San José-Maderuelo

  7. Servicio Oncología Radioterápica-ERESA, Hospital General Universitario de Valencia, Avenida Tres Cruces nº2, 46014, Valencia, Spain

    J. Pastor Peidro & J. López-Torrecilla

  8. Radiation Oncology, Hospital Universitario Virgen de las Nieves, Av. de las Fuerzas Armadas, 2, Granada, Spain

    J. Expósito-Hernández

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  1. A. J. Conde-Moreno
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  2. J. L. Lopez-Guerra
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  3. V. A. Macias
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Correspondence to A. J. Conde-Moreno.

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This is a guideline, based on a review of clinical studies, but it is not a research study with patients.

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This is a guideline, based on a review of clinical studies, but it is not a research study with human participants and/or animals.

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Conde-Moreno, A.J., Lopez-Guerra, J.L., Macias, V.A. et al. Spanish Society of Radiation Oncology clinical guidelines for stereotactic body radiation therapy in lymph node oligometastases. Clin Transl Oncol 18, 342–351 (2016). https://doi.org/10.1007/s12094-015-1383-y

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