The increase in striatal neuropeptide Y immunoreactivity induced by neonatal dopamine-depleting lesions in rats is reversed by intrastriatal dopamine-rich transplants
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Cited by (9)
The neonate-6-hydroxydopamine-lesioned rat: A model for clinical neuroscience and neurobiological principles
2005, Brain Research ReviewsCitation Excerpt :Upon exposure to l-DOPA, substance P is decreased further in the neonate-lesioned animals, whereas the elevation of enkephalin is further increased [143]. While a unilateral lesion to dopaminergic neurons in neonate rats increases striatal neuropeptide Y, a similar increase is also observed in rats given this lesion as adults [1]. The level of this peptide in the bilaterally neonate-lesioned rats has not been determined.
Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae
1996, Progress in NeurobiologyIncreased GABAergic transmission in neuropeptide Y-expressing neurons in the dopamine-depleted murine striatum
2020, Journal of Neurophysiology
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