Elsevier

Veterinary Parasitology

Volume 7, Issue 3, November 1980, Pages 243-254
Veterinary Parasitology

Differentiation of resistance in cattle to larval Hypoderma lineatum

https://doi.org/10.1016/0304-4017(80)90028-XGet rights and content

Abstract

Cattle were successively infested for 4 years with larval cattle grubs, Hypoderma lineatum, to demonstrate the acquisition of resistance. The effects of host age and dietary-induced state with Vitamin A on susceptibility to infestation and their interactions with effects from previous infestations were also determined.

Cattle acquired resistance to infestation after a single infestation. This resistance was not affected by host age for at least 4 years, was not affected by a deficiency of vitamin A, and was effective in the skin and connective tissues of the host. The effects of this acquired resistance were highly variable in degree, were produced primarily during the first 90 days of infestation and increased after repeated provocation to provide nearly complete protection in some animals.

Calves and yearlings had innate resistance that decreased with age, was localized in the skin, was impaired by a deficiency of Vitamin A, and resulted in a mean loss of 65–75% of the larvae in an infestation dose of up to 150.

The combined effects of the 2 types of resistance reduced the grub-burden in cattle throughout their life.

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