Chapter 3 - Safety and toxicity concerns of nanosystems
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Undaria pinnatifida fucoidan nanoparticles loaded with quinacrine attenuate growth and metastasis of pancreatic cancer
2021, International Journal of Biological MacromoleculesCitation Excerpt :These results further confirmed the ability of nanoformulations to enhance drug delivery compared to QC solution leading to a decrease in tumor volume that was reflected as a decrease in tumor serum biomarker CA 19-9. Safety of the prepared nanoformulations remained the most important question to be answered since the development of nanosystems for drug delivery [79]. Nanoparticles have very small size and large surface area resulting in a change in their physicochemical properties which might have some undesirable effect on body organs.
Physicochemical characterization of bioactive compounds in nanocarriers
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