First examples of dammarane triterpenes isolated from Celastraceae
Eight new dammarane triterpenes were isolated from Maytenus Macrocarpa. Their structures were determined by means of 1H and 13C NMR spectroscopic studies, including 1H-13C heteronuclear correlation (HETCOR), long range correlation with inverse detection (HMBC), and chemical evidence. This is the first time that dammarane triterpenes have been isolated from Celastraceae.
References (12)
- et al.
Tetrahedron
(1992) - et al.
Tetrahedron
(1996) - et al.
Bioorg. Med. Chem.
(1996) - et al.
Phytochemistry
(1992) - et al.
Phytochemistry
(1982)
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Three new inositol derivatives from Chisocheton paniculatus
2019, Tetrahedron LettersCitation Excerpt :To the best of our knowledge, this is the first report for the isolation of inositol derivatives with 5-hydroxytigloyloxy group. The other isolated compounds were identified as 6α,7α-diacetoxy-23-hydroxy-3-oxo-24,25,26,27-tetranorapotirucall-1,14,20(22)-trien-21,23-olide (4) [6], (24E)-3-oxo-dammara-20,24-dien-26-ol (5) [7], vismiaefolic acid (6) [8], and δ-tocopherol (7) [9], (Fig. 1), based on their spectroscopic data including 1D and 2D NMR data and comparisons with those reported in the literature. Natural products have played a very important role as established cancer chemotherapeutic agents [10], and we have so far searched naturally occurring cytotoxic compounds against human cancer cell lines.
Plant use in the medicinal practices known as "strict diets" in Chazuta valley (Peruvian Amazon)
2011, Journal of EthnopharmacologyCitation Excerpt :Friedelane triterpenoids have shown antinflammatory, analgesic (Chaturvedi et al., 1974; Duwiejua et al., 1999; Nakamura et al., 1997), antibacterial and antifungal activities (Jain and Singh, 1999; Singh and Dubey, 2001) and anti-HIV activity (Kuo and Yang-Kio, 1997). M. macrocarpa contains dammarane triterpenes (Chavez et al., 1997). This class of compounds has shown, in general, antinflammatory, analgesic (Akihisa et al., 1997; Ozaki et al., 2000; Rouf et al., 2001; Yasukawa et al., 2000) antimicrobial (Gonzalez et al., 1996), and antiviral activities (Inada et al., 1993; Kaij-A-Kamb et al., 1992; Madureira et al., 2003; Zhang et al., 2003).
Antimicrobial activity of some medicinal barks used in Peruvian Amazon
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