Case Report
Seronegative disseminated Bartonella spp. infection in an immunocompromised patient

https://doi.org/10.1016/j.apjtm.2016.11.001Get rights and content
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Abstract

An 11 year old, hispanic girl with a history of B-cell acute lymphoblastic leukemia was admitted to the hospital for symptoms compatible with Bartonella henselae infection. The first molecularly diagnosed case of disseminated Bartonella henselae infection was reported in an immunocompromised patient in Lima, Peru. The analysis was confirmed by Polymerase Chain Reaction and automated sequencing of a liver biopsy sample, even though the serologic tests were negative. In conclusion, Bartonella spp. infection should have a particular diagnostic consideration in immunocompromised patients with fever of unknown origin and further investigation regarding the patient's past exposures with cats should also be elicited.

Keywords

Bartonella spp.
Bartonella henselae
B-cell acute lymphoblastic leukemia
Peru

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First author: Claudia Weilg, Medicine School, Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.

Foundation Project: It was partially supported by the Programa Nacional de Innovación para la Competitividad y Productividad (Innóvate Perú), under the contract 117-PNICP-PIAP-2015.

Peer review under responsibility of Hainan Medical University.