Trends in Microbiology
SpotlightBap: A New Type of Functional Amyloid
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Cited by (18)
Targeting hydrophobicity in biofilm-associated protein (Bap) as a novel antibiofilm strategy against Staphylococcus aureus biofilm
2022, Biophysical ChemistryCitation Excerpt :In this study, while we have putatively identified regions of high conservation and with high antigen propensity, further research efforts need to made in this direction. This study adds to previous research in which domain B of the Bap protein was identified as a domain with significant functional properties [19,60]. Bap, having been covalently linked to the cell surface, has always been believed to mediate cell-to-cell adherence via homophilic interactions between Bap proteins expressed on the surfaces of neighbouring cells.
3D structure determination of amyloid fibrils using solid-state NMR spectroscopy
2018, MethodsCitation Excerpt :These amyloids, executing native cellular functions, have been identified in a range of organisms from bacteria to mammals and are termed “functional amyloids“ [12–18]. Hydrophobins, biofilm formation, hormone storage, cellular signal transduction or yeast prions are some of many examples illustrating the presence of amyloid-like systems involved in biological processes [19–26]. Such duality of effects, non-native aggregation and functional assembly, reveals the complexity of the amyloid fold.
Hierarchical biopolymer-based materials and composites
2023, Journal of Polymer Science