The importance of a human 3D database and atlas for studies of prefrontal and thalamic functions

doi:10.1016/S0079-6123(00)26024-X

Progress in Brain Research

Volume 126, 2000, Pages 357-368

https://doi.org/10.1016/S0079-6123(00)26024-X Get rights and content

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This chapter discusses the inter-individual variability in the brain regions and the need for a probabilistic atlas instead of the Talairach atlas. This point is illustrated for a few prefrontal cortical areas and for the thalamus. It is reported, in view of the very large inter-individual variability of brain regions, the cortical areas in particular, establishing a probabilistic 3-D atlas for microscopically defined brain areas is required. It is then possible to localize the functional activity of individual persons and/or a group of subjects in an appropriate, probabilistic way. This also improve the view of which cortical systems are involved in mental disorders and specific cognitive functions and lead to appropriate hypotheses on the underlying brain circuits. Without a probabilistic atlas, it is very well possible that the wrong conclusions are drawn about the cortical areas involved in certain processes. Until this probabilistic 3-D atlas becomes available, it is unavoidable to use a description with reference to the macroscopically visible sulci and gyri.

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The importance of a human 3D database and atlas for studies of prefrontal and thalamic functions

Publisher Summary

NeuroImage

NeuroImage

NeuroImage

Trends Neurvsci.

NeuroImage

NeuroImage

Broca's region re-visited: Cytoarchitecture and intersubject variability

J. Camp. Neurol.

Architecture and intrinsic connections of the prefrontal cortex in the rhesus monkey

J. Comp. Neurol.

Vergleichende Lokalisationslehre der Grosshirnrinde

Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey

J. Comp. Neurol.

Comparing spatial normalization procedures

NeuroImage

Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression

Orbital frontal cortex: historical and contemporary views about its behavioral and physiological significance. An introduction to special topic papers: part I

Neurocase

Uber die Variabilität der Grosshirn rindenstruktur. Mitt. 2: Regio occipitalis beim erwachsenen Menschen

J. Psychol. Neurol.

Gender differences in age effect on brain atrophy measured by MRI

Architectonic organization of the thalamic nuclei

A description of the human thalamus

Principles of Neural Science

The variability of structure of the cortex of the brain: inferior frontal gyrus of adult man

Brain Res. Inst. Publ.

Cytoarchitecture and neural afferents of orbitofrontal cortex in the brain of the monkey

J. Comp. Neurol.

Multi-architectonic and stereotactic atlas of the human thalamus

J. Comp. Neurol.

Glial reduction in the subgenual prefrontal cortex in mood disorders

Human cingulate and paracingulate sulci: pattern, variability, asymmetry and probabilistic map

Cereb. Cort.

Comparative architectonic analysis of the human and the macaque frontal cortex