Research reportAnxiety- and activity-related effects of diazepam and chlordiazepoxide in the rat light/dark and dark/light tests
References (28)
Tests of emotionality in rats and mice: a review
Animal Behav.
(1973)- et al.
Comparison of different behavioral test situations in psychopharmacology for measurement of anxiety
Physiol Behav.
(1994) - et al.
Link between emotional memory and anxiety states: a study by principal component analysis
Physiol Behav.
(1995) - et al.
Male Fischer 344 and Lewis rats display differences in locomotor reactivity, but not in anxiety-related behaviours: relationships with the hippocampal serotonergic system
Brain Res.
(1995) - et al.
Exploration of mice in a black and white test box: validation as a model of anxiety
Pharmacol. Biochem. Behav.
(1989) Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines
Pharmacol. Biochem. Behav.
(1981)- et al.
Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
Pharmacol. Biochem. Behav.
(1980) - et al.
Ethopharmacological analysis of rat behavior on the elevated plus-maze
Pharmacol. Biochem. Behav.
(1994) - et al.
Use of the elevated plusmaze in the search for novel anxiolytics
Trends Pharmacol. Sci.
(1995) - et al.
Effects of anxiolytic and anxiogenic drugs on exploratory activity in a simple model of anxiety in mice
Neuropharmacology
(1989)
Modulation of baseline behavior in rats by putative serotonergic agents in three ethoexperimental paradigms
Behav. Neural Biol.
(1990)
Ethologically-based animal models of anxiety disorders
Pharmacol. Ther.
(1990)
Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
J. Neurosci. Methods
(1985)
Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety
Pharmacol. Biochem. Behav.
(1995)
Cited by (150)
Benzodiazepine derivatives for the treatment of neuropharmacological disorders and pain management: Docking investigations and in-vivo studies
2024, Journal of Molecular StructureExploring the light/dark box test: Protocols and implications for neuroscience research
2023, Journal of Neuroscience MethodsCitation Excerpt :This paradigm is widely used in anxiety models such as the elevated plus maze (EPM), the open-field test (OFT), and the light-dark box test (LDB) (Ohl, 2003). Anxiolytic drugs increase the exploration of aversive areas and/or decrease the avoidance of such areas depending on the apparatus (Chaouloff et al., 1997; Bilkei-Gorzó et al., 1998; Griebel et al., 1994; Merlo Pich and Samanin, 1989). Stressful experiences may also induce anxiety-like states in rodents (Padovan and Guimarães, 2000; Novaes et al., 2017; Calvo et al., 1998; Lazarini-Lopes et al., 2020) and humans (Grillon et al., 2007).
Acute stress increases behaviors that optimize safety and decreases the exploration of aversive areas
2022, Learning and MotivationEndocannabinoids, cannabinoids and the regulation of anxiety
2021, Neuropharmacology
Copyright © 1997 Published by Elsevier B.V.