Issue 43, 2008

Sensitive liposomes encoded with oligonucleotideamphiphiles: a biocompatible switch

Abstract

DNA-tagged liposomes made of DOPC specifically bind to a fluorescently labelled complementary ss-DNA with virtually no influence from the lipid bilayer despite the absence of a linker; depending on an external stimulus, either physical (temperature) or chemical (competitive complementary ON sequences), the liposomes switch between an on and off fluorescent state depending on the location of the probe either at the surface or in the bulk.

Graphical abstract: Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch

Supplementary files

Article information

Article type
Communication
Submitted
18 Jul 2008
Accepted
26 Aug 2008
First published
23 Sep 2008

Chem. Commun., 2008, 5550-5552

Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch

A. Gissot, C. Di Primo, I. Bestel, G. Giannone, H. Chapuis and P. Barthélémy, Chem. Commun., 2008, 5550 DOI: 10.1039/B812398E

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