Journal of Biological Chemistry
NeurobiologyTau Monoclonal Antibody Generation Based on Humanized Yeast Models: IMPACT ON TAU OLIGOMERIZATION AND DIAGNOSTICS*
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This paper is dedicated to Skip Binder as a token of our appreciation for his generosity and his scientific legacy, which includes numerous and significant contributions to the Tau field.
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This work was supported by grants from the Research Foundation Flanders (FWO-Vlaanderen) (to J. W. and S. E.), KU Leuven Research Fund (KU Leuven-BOF; KU Leuven-IOF), KU Leuven R&D (to J. W.), and the Agency for Innovation by Science and Technology (IWT) (to J. W., E. V., and S. E.). This work was also supported by an IWT Ph.D. fellowship (to J. V. d. B.) and FWO-Vlaanderen postdoctoral fellowships (to M. C. and E. S.). This work was also supported through the LabEx DISTALZ (Excellent Laboratory-Development of Innovative Strategies for a Transdisciplinary Approach to Alzheimer's Disease), the CNRS Large Scale Facility NMR THC Fr3050, INSERM, CNRS, University of Lille 2, Lille Métropole Communauté Urbaine (LMCU), Région Nord/Pas-de-Calais, FEDER, the University of Antwerp Research Fund, the Alzheimer Research Foundation (SAO-FRA), the central Biobank facility of the Institute Born-Bunge/University Antwerp, the Belgian Science Policy Office Interuniversity Attraction Poles (IAP) program, and the Flemish Government initiated Methusalem excellence grant. J. W. and E. V. are both co-founders of ADx NeuroSciences and co-inventors on the patent entitled Antibodies to Phosphorylated Tau Aggregates (WO2013007839 (A1)).
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These authors contributed equally to this work.
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Present address: CODA-CERVA, Groesenlenberg 80, 1180 Brussels, Belgium.