Journal of Biological Chemistry
Volume 292, Issue 43, 27 October 2017, Pages 17897-17908
Molecular Bases of DiseaseHistone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease
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AMP
calcium
calcium ATPase
calcium channel
calcium intracellular release
calmodulin (CaM)
histone deacetylase 6 (HDAC6)
histone deacetylase inhibitor (HDAC inhibitor) (HDI)
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L. C. received a contract from Acetylon Corp. to study a company-derived HDAC6 inhibitor different from the one studied here. There is no overlap with this study.
© 2017 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.