Journal of Biological Chemistry
Volume 293, Issue 22, 1 June 2018, Pages 8439-8448
ImmunologyStructural insights into the mechanism of action of a biparatopic anti-HER2 antibody
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analytical ultracentrifugation
antibody
crystallography
epitope mapping
phosphorylation
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This work was supported by MedImmune LLC. The authors declare that they have no conflicts of interest with the contents of this article.
This article contains Fig. S1.
The atomic coordinates and structure factors (code 6ATT) have been deposited in the Protein Data Bank (http://wwpdb.org/).
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Present address: Palleon Pharmaceuticals, 266 Second Ave., Waltham, MA 02451.
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Present address: MacroGenics, 9704 Medical Center Dr., Rockville, MD 20850.
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Present address: Salubris Biotherapeutics, Inc., 45 W Watkins Mill Rd., Gaithersburg, MD 20878.
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Present address: Agilis Biotherapeutics, 245 First St., Ste. 1800, Cambridge, MA 02142.
© 2018 by The American Society for Biochemistry and Molecular Biology, Inc.