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Quantitative assessment of spasticity in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis

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Abstract

People with human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) develop spasticity. The authors examined 34 patients with HAM/TSP in Perú using a device that measures tone in the gastroc-soleus-Achilles tendon unit and provides a quantitative spasticity assessment (QSA). Tone in the 34 patients was more than double that of women with asymptomatic HTLV-I infection. The device may help to track progression in HTLV-I infection.

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Authors and Affiliations

  1. Department of Neurology, University of Washington School of Medicine, Seattle, Washington, USA

    J. R. Zunt & W. T. Longstreth

  2. Instituto de Ciencias Neurológicas, Lima, Perú

    S. M. Montano

  3. Universidad Nacional Mayor de San Marcos, Lima, Perú

    J. O. V. Alarcón

  4. Department of Epidemiology, University of Washington School of Medicine, Seattle, Washington, USA

    W. T. Longstreth & K. K. Holmes

  5. Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, Washington, USA

    R. Price

  6. Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA

    J. R. Zunt & K. K. Holmes

  7. Center for AIDS and STD, University of Washington School of Medicine, Seattle, Washington, USA

    K. K. Holmes

  8. Department of Neurology, MPH, Harborview Medical Center, 325 Ninth Avenue South, Box 359775, 98104, Seattle, WA, USA

    J. R. Zunt

Authors
  1. J. R. Zunt
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  2. S. M. Montano
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  3. J. O. V. Alarcón
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  4. W. T. Longstreth
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  5. R. Price
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  6. K. K. Holmes
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Corresponding author

Correspondence to J. R. Zunt.

Additional information

This work was supported by NIH grants K23-AI01600, TW00679, and AI0714P, Fogarty International grant T22-TW00001, and the University of Washington Center for AIDS Research (CFAR) grant AI27757.

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Zunt, J.R., Montano, S.M., Alarcón, J.O.V. et al. Quantitative assessment of spasticity in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis. Journal of NeuroVirology 11, 70–73 (2005). https://doi.org/10.1080/13550280590900571

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  • DOI: https://doi.org/10.1080/13550280590900571

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