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Volume 168, Issue 4

Presence and absence of type VI secretion systems in bacteria Open Access

This article is part of the Bacterial Cell Envelopes collection.

Abstract

The type VI secretion system (T6SS) is a molecular puncturing device that enables Gram-negative bacteria to kill competitors, manipulate host cells and take up nutrients. Who would want to miss such superpowers? Indeed, many studies show how widespread the secretion apparatus is among microbes. However, it is becoming evident that, on multiple taxonomic levels, from phyla to species and strains, some bacteria lack a T6SS. Here, we review who does and does not have a type VI secretion apparatus and speculate on the dynamic process of gaining and losing the secretion system to better understand its spread and distribution across the microbial world.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): comparative genomics , horizontal gene transfer , intraspecific variation , mobile genetic elements , presence/absence variation , T6SS subtypes and type VI secretion system
Funding
This study was supported by the:
  • Max-Planck-Gesellschaft (Award IMPRS EvolBio)
    • Principle Award Recipient: RahulUnni
  • Bundesministerium für Bildung und Forschung (Award 01KI2020)
    • Principle Award Recipient: DanielUnterweger
  • Deutsche Forschungsgemeinschaft (Award CRC1182 B4)
    • Principle Award Recipient: DanielUnterweger
  • Deutsche Forschungsgemeinschaft (Award Manuscript_Revision.docx)
    • Principle Award Recipient: AndreasDiepold
© 2022 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
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2022-04-25
2024-05-05
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http://instance.metastore.ingenta.com/content/journal/micro/10.1099/mic.0.001151
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Presence and absence of type VI secretion systems in bacteria
Microbiology 168, 001151 (2022); https://doi.org/10.1099/mic.0.001151
/content/journal/micro/10.1099/mic.0.001151
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