Thermally induced birefringence changes in cartilage using polarization-sensitive optical coherence tomography

Jong-In Youn; Gracie Vargas; Mathieu G. Ducros; Sergey A. Telenkov; Brian Jet-Fei Wong M.D.; Thomas E. Milner

doi:10.1117/12.434742

9 July 2001 Thermally induced birefringence changes in cartilage using polarization-sensitive optical coherence tomography

Jong-In Youn, Gracie Vargas, Mathieu G. Ducros, Sergey A. Telenkov, Brian Jet-Fei Wong M.D., Thomas E. Milner

Author Affiliations +

Proceedings Volume 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical; (2001) https://doi.org/10.1117/12.434742
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Thermodynamic induced changes in birefringence of nasal septal cartilage following Nd:YAG laser irradiation were investigated using a polarization-sensitive optical coherence tomography (PSOCT) system. Birefringence in cartilage is due to the asymmetrical collagen fibril structure and may change if the underlying structure is disrupted due to local heat generation by absorption of laser radiation. A PSOCT instrument and an infrared imaging radiometer were used to record, respectively, depth-resolved images of the Stokes parameters of light backscattered from ex vivo porcine nasal septal cartilage and radiometric temperature following laser irradiation. PSOCT images of cartilage were recorded before (control), during, and after laser irradiation. From the measured Stokes parameters (I,Q,U, and V), an estimate of the relative phase retardation between two orthogonal polarizations was computed to determine birefringence in cartilage. Stokes parameter images of light backscattered from cartilage show significant changes due to laser irradiation. From our experiments we differentiate dehydration and thermal denaturation effects and observe the birefringence changes only in the dehydration effect. Therefore, a dynamic measurement of birefringence changes in cartilage using PSOCT as a feedback control methodology to monitor thermal denaturation is problematic in non-ablative surgical procedures such as laser assisted cartilage reshaping.

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Jong-In Youn, Gracie Vargas, Mathieu G. Ducros, Sergey A. Telenkov, Brian Jet-Fei Wong M.D., and Thomas E. Milner "Thermally induced birefringence changes in cartilage using polarization-sensitive optical coherence tomography", Proc. SPIE 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, (9 July 2001); https://doi.org/10.1117/12.434742

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