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Research Note

Massive open online courses on biomedical informatics

[version 1; peer review: 2 not approved]
PUBLISHED 14 Feb 2019
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This article is included in the Bioinformatics Education and Training Collection collection.

Abstract

This study aimed to identify the characteristics of massive open online courses (MOOCs) related to biomedical informatics offered in several plataforms. We conducted an observational study on specialized MOOCs platforms to find courses related to biomedical informatics, in 2018. Our search identified 67 MOOCs on biomedical informatics. The majority of MOOCs were offered by Coursera (71.6%, 48/67), English was the most common language (95.5%, 64/67). The United States developed the majority of courses (73.1%, 49/67), with the vast majority of MOOCs being offered by universities (94%, 63/67). The majority of MOOCs were in bioinformatics (56.7%, 38/67) and data science (47.7%, 32/67). In conclusion, the MOOCs on biomedical informatics were focused in bioinformatics and data science, and were offered in English by institutions in the developing world.

Keywords

computer-assisted instruction, medical informatics, bioinformatics, education, continuing education

Introduction

Biomedical informatics (BI) is “the interdisciplinary field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving and decision making, motivated by efforts to improve human health”1. BI has an important role in healthcare therefore health professionals well-trained in the use of information and communication technology are needed2.

In developing countries, a few of they have developed training programmes in biomedical or health informatics3. These programmes are short courses, Master’s programmes and even sub-specialty programmes3. However, these do not supply the need for health professionals with BI skills. The internet allows health professionals to have easy access to educative sources through platforms such massive open online courses (MOOCs)4.

MOOCs are accessible through the web and open to registration for people all around the world that want to participate in higher education courses; they are recognized for their educational quality and flexibility schedules4,5. MOOCs materials are free of charge, however, in some courses one can pay to get a certificate of completion4,5.

They represent one strategy to reduce costs and enable continuous education in developing countries; especially learners with English language proficiency, computer literacy, and internet access5. This study aimed to identify the characteristics of MOOCs related to biomedical informatics.

Methods

A search of MOOCs was performed in several learning platforms, including Coursera®, EdX®, FutureLearn®, Udacity®, FunMOOC®, UniMOOC®, MiriadaX®, Alison®, Iversity®, Open2Study® and P2PU®, in order to find courses about biomedical informatics. The search was made from 31 October to 27 November, 2018. The following keywords were used: biomedical informatics, telemedicine, telehealth, remote consultation, mobile health, mHealth, eHealth, medicine technology, biomedical technology, IT Health and bioinformatics.

Information was obtained on the platform where the MOOC was hosted, data regarding the institution offering the course, and the original language. The disciplines were categorized into: Bioinformatics, Images, Clinical Informatics, Public Health Informatics and Data science (a course could approach more than one discipline). Likewise, the data of the duration of the course and its cost in dollars were also obtained.

The data obtained were analyzed in STATA version 14. The categorical results were reported by frequencies and percentages, while the numerical results were reported by measures of central tendency and dispersion, after analysis of normality using the Shapiro-Wilk test.

Results

The analyses of the data identified 67 MOOCs offered on biomedical informatics in the world. The majority (71.64%) were offered by Coursera, followed by EdX (13.43%) and FutureLearn (13.43%). The majority of MOOCs were offered from institutes from the United State of America (73.13%). Out of these, the majority were offered by universities. The large majority of these MOOCs, were offered by the University of California San Diego, followed by Johns Hopkins University. Finally the language breakdown of MOOCs related to biomedical informatics shows that the vast majority of MOOCs ( 95.52%) were offered in English (Table 1). The details of each course are shown in the Table 2.

Table 1. Characteristics of massive open online courses about biomedical informatics.

(N =67)%
Plataform
    Coursera4871.64
    EdX913.43
    FutureLearn913.43
    Udacity11.49
Country
    United States of America4973.13
    China34.48
    United Kingdom34.48
    Russia34.48
    Denmark22.99
    Netherland22.99
    Others57.46
University
    Yes6394.03
    No45.97
Institutions
    University of California San Diego1420.90
    Johns Hopkins University811.94
    Icahn School of Medicine at Mount Sinai68.98
    Columbia University34.48
    Georgia Institute of Technology34.48
    University of Illinois34.48
    Others3044.74
Original lenguaje
    English6495.52
    Ruso34.48

Table 2. Characteristics of each massive open online course on biomedical informatics.

IDPlatformCourse nameInstitutionLenguage
(Subtitle)
Topic
BioinformaticsImagesClinicPublic
health
Data
Science
1CourseraAlgorithms for DNA
Sequencing
Johns Hopkins
University
English
(English)
XX
2CourseraAlgorithms on StringsUniversity of
California San
Diego
English
(English)
X
3CourseraAnalysis of AlgorithmsPrinceton
University
English
(English)
X
4CourseraBasics of Extracellular
Vesicles
University of
California,
Irvine
English
(English)
X
5CourseraBig Data Science
with the BD2K-LINCS
Data Coordination and
Integration Center
Icahn School
of Medicine at
Mount Sinai
English
(English)
X
6CourseraBig Data, Genes, and
Medicine
University of
New York
English
(English)
XX
7CourseraBioconductor for
Genomic Data Science
Johns Hopkins
University
English
(English)
X
8CourseraBioinformatic Methods IUniversity of
Toronto
English
(English)
X
9CourseraBioinformatic Methods IIIcahn School
of Medicine at
Mount Sinai
English
(English)
X
10CourseraBioinformatics Capstone:
Big Data in Biology
University of
California San
Diego
English
(English)
XX
11CourseraBioinformatics:
Introduction and Methods
生物信息学: 导论与方法
Peking
University
English
(English)
XX
12CourseraBiology Meets
Programming:
Bioinformatics for
Beginners
University of
California San
Diego
English
(English,
Portuguese)
X
13CourseraCommand Line Tools for
Genomic Data Science
Johns Hopkins
University
English
(English)
XX
14CourseraComparing Genes,
Proteins, and Genomes
(Bioinformatics III)
University of
California San
Diego
English
(English)
X
15CourseraData Science in Stratified
Healthcare and Precision
Medicine
The University
of Edinburgh
English
(English)
XXX
16CourseraDynamical Modeling
Methods for Systems
Biology
Icahn School
of Medicine at
Mount Sinai
English
(English)
XX
17CourseraeHealth: More than just
an electronic record
The University
of Sydney
English
(English)
X
18CourseraFinding Hidden
Messages in DNA
(Bioinformatics I)
University of
California San
Diego
English
(English)
X
19CourseraFinding Mutations in
DNA and Proteins
(Bioinformatics VI)
University of
California San
Diego
English
(English)
X
20CourseraGenome Assembly
Programming Challenge
University of
California San
Diego
English
(English)
X
21CourseraGenome Sequencing
(Bioinformatics II)
University of
California San
Diego
English
(English)
XX
22CourseraGenomic Data Science
and Clustering
(Bioinformatics V)
University of
California San
Diego
English
(English)
XX
23CourseraGenomic Data Science
Capstone
Johns Hopkins
University
English
(English)
X
24CourseraGenomic Data Science
with Galaxy
Johns Hopkins
University
English
(English)
XX
25CourseraGenomics: Decoding
the Universal Language
of Life
University
of Illinois
at Urbana-
Champaign
English
(English)
XX
26CourseraHealth Care IT:
Challenges and
Opportunities
Icahn School
of Medicine at
Mount Sinai
English
(English)
X
27CourseraHealth Informatics on
FHIR
Georgia
Institute of
Technology
English
(English)
XX
28CourseraHI-FIVE: Health
Informatics For
Innovation, Value
& Enrichment
(Administrative/IT
Perspective)
Columbia
University
English
(English)
X
29CourseraHI-FIVE: Health
Informatics For
Innovation, Value &
Enrichment (Clinical
Perspective)
Columbia
University
English
(English)
X
30CourseraHI-FIVE: Health
Informatics For
Innovation, Value &
Enrichment (Social/Peer
Perspective)
Columbia
University
English
(English)
X
31CourseraIntegrated Analysis in
Systems Biology
Icahn School
of Medicine at
Mount Sinai
English
(English)
X
32CourseraInterprofessional
Healthcare Informatics
University
of Minnesota
English
(English)
X
33CourseraIntroduction to Genomic
Technologies
Johns Hopkins
University
English
(English)
X
34CourseraJulia Scientific
Programming
University of
Cape Town
English
(English)
X
35CourseraMathematical Thinking in
Computer Science
University of
California San
Diego
English
(English)
X
36CourseraMetagenomics applied to
surveillance of pathogens
and antimicrobial
resistance
Technical
University of
Denmark
English
(English)
X
37CourseraMolecular Evolution
(Bioinformatics IV)
University of
California San
Diego
English
(English)
XX
38CourseraNetwork Analysis in
Systems Biology
Icahn School
of Medicine at
Mount Sinai
English
(English)
X
39CourseraPattern Discovery in Data
Mining
University
of Illinois
at Urbana-
Champaign
English
(English)
X
40CourseraPrograma especializado
Bioinformatics
University of
California San
Diego
English
(English,
Chinese)
X
41CourseraPrograma especializado
Data Mining
University
of Illinois
at Urbana-
Champaign
English
(English)
XX
42CourseraPrograma especializado
Data Structures and
Algorithms
University of
California San
Diego
English
(English,
Spanish)
X
43CourseraPrograma especializado
Genomic Data Science
Johns Hopkins
University
English
(English,
Russian)
XX
44CourseraPrograma especializado
Машинное обучение и
анализ данных
Moscow
Institute of
Physics and
Technology
Ruso
(Russian)
X
45CourseraPython for Genomic Data
Science
Johns Hopkins
University
English
(English)
X
46CourseraWhole genome
sequencing of bacterial
genomes - tools and
applications
Technical
University of
Denmark - DTU
English
(English)
X
47CourseraВведение в
биоинформатику
(Introduction to
Bioinformatics)
Saint
Petersburg
State University
Russian
(Russian)
XX
48CourseraВведение в
Биоинформатику:
Метагеномика
(Introduction to
Bioinformatics:
Metagenomics)
Saint
Petersburg
State University
Russian
(Russian,
English)
XX
49EdXBig Data Analytics in
Healthcare
Georgia
Institute of
Technology
English
(English
XX
50EdXBioinformaticsUniversity of
maryland
English
(English)
X
51EdXData Analytics in
Health – From Basics to
Business
KU Leuven
University
English
(English)
XX
52EdXDemystifying Biomedical
Big Data: A User’s Guide
Georgetown
University
English
English)
XX
53EdXeHealth – Opportunities
and Challenges
Karolinska
Institutet
English
(English)
X
54EdXGlobal Health Informatics
to Improve Quality of
Care
Massachusetts
Institute of
Technology
English
(English)
X
55EdXIntroduction to Genomic
Data Science
University of
California San
Diego
English
(English)
XX
56EdXMedicine in the Digital
Age
Rice UniversityEnglish
(English)
X
57EdXTrends in e-PsychologyKU Leuven
University
English
(English)
X
58FutureLearnBacterial Genomes: From
DNA to Protein Function
Using Bioinformatics
Wellcome
Genome
Campus
Advanced
Courses and
Scientific
Conferences
English
(English)
X
59FutureLearnClinical Bioinformatics:
Unlocking Genomics in
Healthcare
The University
of Manchester
English
(English)
XX
60FutureLearnData Science for
Healthcare: Using Real
World Evidence
EIT HEALTHEnglish
(English)
X
61FutureLearnDigital Health for Cancer
Management: Smart
Health Technologies in
Complex Diseases
Taipei Medical
University
English
(English,
Chinese)
X
62FutureLearneHealth: Combining
Psychology, Technology
and Health
University of
Twente
English
(English)
X
63FutureLearnHealth Data and AnalyticsEIT HEALTHEnglish
(English)
X
64FutureLearnProtecting Health Data in
the Modern Age: Getting
to Grips with the GDP
University of
Groningen
English
(English)
X
65FutureLearnSocial Media in
Healthcare: Opportunities
and Challenges
Taipei Medical
University
English
(English,
Chinese)
X
66FutureLearnThe Power of Data in
Health and Social Care
University of
Strathclyde
English
(English)
X
67UdacityHealth Informatics in the
Cloud
Georgia
Institute of
Technology
English
(English)
XX

From the MOOCs, disciplines related to biomedical informatics courses were analyzed. Some courses taught more than one subject at a time. The majority of these MOOCs, 56.72% (n = 38), were in bioinformatics and 47.76% (n = 32) in data science (Figure 1).

0d86df87-5085-42fb-9607-d514ec644187_figure1.gif

Figure 1. Disciplines addressed in MOOCs on biomedical informatics.

The average cost of the courses was $49, which ranged from zero cost (free) to $672. Likewise, the average length of the MOOCs considered for the review was 5 weeks (Min: 2, Max: 36), with an average activity of 3 hours per week (Min: 1, Max: 30).

Discussion

Within the educational platforms, Coursera® offered the majority of courses focused on BI, as showed in a previous study of health and medicine5; authors prefer to upload their content more often in Coursera® because this is the most used platform6.

Regarding the countries, The United States, China, and the United Kingdom develop the majority of courses. There appears to be a correlation between countries that generate more MOOCs and those with higher scientific output7. It’s important to consider that Russia appears among the leading developers of MOOCs; this could be explained by the student exchanges that the Russian educational institutions have been promoting8.

The majority of courses were offered in English, with a few having subtitles in other languages such as in previous studies9. A possible explanation for this might be the vast majority of them were made in an English-speaking country. Another explanation could be the development level of BI in these countries.

Most courses approached both bioinformatics and data science, maybe because both are tools to personalized medicine and this was been a growing field in the last few years10. Therefore it is necessary to develop more courses focused on health informatics.

This study has some limitations, such as such as only English language courses being included, and the incomplete coverage of all MOOC platforms. However, the platforms studied are those that have the most health or medicine courses5. This is the first study that has assessed MOOCs in the area of BI. In addition, the data shows a list with all the names, languages and prices of the courses.

The recommendation of this study is to diversify the BI courses into other disciplines. We suggest further studies in this area that focus on evaluating the quality of MOOCs.

Conclusion

The majority of MOOCs on Biomedical informatics were focused in bioinformatics and data science, they were offered in English by institutions in the developing world.

Data availability

Underlying data is available from figshare

Figshare: Dataset 1. Data base of Massive Open Online Courses on Biomedical Informatics https://doi.org/10.6084/m9.figshare.7582016.v211

Licence: CC0 1.0 Universal

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Quispe-Juli CU, Moquillaza-Alcántara VH and Arapa-Apaza K. Massive open online courses on biomedical informatics [version 1; peer review: 2 not approved] F1000Research 2019, 8:180 (https://doi.org/10.12688/f1000research.17693.1)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.
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ApprovedThe paper is scientifically sound in its current form and only minor, if any, improvements are suggested
Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.
Not approvedFundamental flaws in the paper seriously undermine the findings and conclusions
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PUBLISHED 14 Feb 2019
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Reviewer Report 25 Feb 2019
Tharindu Liyanagunawardena, University College of Estate Managment, Reading, UK 
Not Approved
VIEWS 27
This study aimed to identify the characteristics of MOOCs related to biomedical informatics and it was an interesting read. However, there are some serious issues in the presentation of this work. I find some of the sentences difficult to parse. ... Continue reading
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Liyanagunawardena T. Reviewer Report For: Massive open online courses on biomedical informatics [version 1; peer review: 2 not approved]. F1000Research 2019, 8:180 (https://doi.org/10.5256/f1000research.19345.r44480)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.
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Reviewer Report 15 Feb 2019
Edward Meinert, Healthcare Translation Research Group, Department of Paediatrics, University of Oxford, Oxford, UK 
Not Approved
VIEWS 67
The authors have developed a manuscript examining the use of biomedical informatics in current MOOC implementations. This contribution could be very useful for those looking to examine MOOC implementations in this subject domain.

There are a few ... Continue reading
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HOW TO CITE THIS REPORT
Meinert E. Reviewer Report For: Massive open online courses on biomedical informatics [version 1; peer review: 2 not approved]. F1000Research 2019, 8:180 (https://doi.org/10.5256/f1000research.19345.r44479)
NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article.

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Alongside their report, reviewers assign a status to the article:
Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested
Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit.
Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions
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