Polyphenolic Compounds, Triterpenes, Carlina Oxide, Antioxidant Activity and Carbohydrate Profile of Different Vegetal Parts of <i>Carlina vulgaris</i> L., <i>Carlina acanthifolia</i> All. and <i>Carlina corymbosa</i> L.
http://www.doi.org/10.26538/tjnpr/v7i10.18
Keywords:
sugars, inulin, fructan, antioxidant activity, phenolic compounds, Carlina genusAbstract
It is known that plants from the Carlina genus possessed many biologic activity due to the bioactive compounds. The current study investigates the phytochemical constituents and antioxidant potential of the different vegetal parts of Carlina vulgaris L., Carlina acanthifolia All. and Carlina corymbosa L. The samples (roots and aerial part) were collected from Bulgaria (Golo Bardo and Vlahina mountains). Total phenols, flavonoids, individual phenolic compounds, triterpenes, phytosterols, carlina oxide, fructans, and individual sugars were determined. Antioxidant potential was evaluated using four methods. The highest total phenolic content was found in ethanol extract from C. acantifololia All. roots. Three phenolic acids (chlorogenic acid, ferulic acid, and salicylic acid), three flavonoids (rutin, hesperidin, and quercetin), and triterpenes (lupeol and betulin) were detected in all samples (mainly in roots). However, p-Coumaric acid and ursolic acid were detected only in C. vulgaris, while carlina oxide was found only in C. acantifololia All. roots. The result showed that the roots of C. acanthifolia All. were characterized by appreciable amounts of total fructans (20 g/100 g dry weight), while inulin represented 18-12 g/100 g of dry weight. Sugars were found in all plant materials. The current study provides data about the chemical composition of extracts obtained from three members of the Carlina genus and their use as a source of antioxidants, phenolic compounds, carlina oxide, and inulin-type prebiotics.
References
Tutin G, Heywood H, Burges A, Moore M, Valentine D, Walters S. Flora Europea. (Vol. 4). Cambridge: Cambridge University Press; 1976. 165 p.
Strzemski M, Wojnicki K, Sowa I, Wojas-Krawczyk K, Krawczyk P, Kocjan R, Such J, Latalski M, Wnorowski A, Wójciak-Kosior M. In vitro antiproliferative activity of extracts of Carlina acaulis subsp. caulescens and Carlina acanthifolia subsp. utzka. Front. Pharmacol. 2017;8(371): 1-11.
Kovanda MI. Observations on Carlina biebersteinii. Thaiszia J. Bot. 2002;12(1):75-82.
Vidović B. A new species and record of Aceria (Acari: Prostigmata: Eriophyoidea) on Carlina spp.(Asteraceae) from Serbia. Zootaxa. 2014;3838(4):486-494.
Stoyanov K, Raycheva T, Cheschmedzhiev I. Key to the native and foreign vascular plants in Bulgaria. Plovdiv: Agricultural University Plovdiv Academic Press; 2021. 96-99 p. (in Bulgarian)
Delipavlov D, Cheshmedzhiev I. Key to the plants in Bulgaria. Plovdiv: Academic Publishing House of the Agricultural University; 2003. 152 p.
Mifsud S. Carlina lanata - datasheet created on July-2005 [Online]. 2022 [cited 2023 Aug] Available from: https://www.maltawildplants.com/ASTR/Carlina_lanata.php
Childs DZ, Rees M, Rose KE, Grubb PJ, Ellner SP. Evolution of size–dependent flowering in a variable environment: construction and analysis of a stochastic integral projection model. Proc. R. Soc. B: Biol. Sci. 2004; 271(1537):425-434.
Petkova N, Saralieva E, Ivanov I, Mihaylova D, Lante A, Denev P. Green methods for extraction of inulin and antioxidants from Carlina acanthifolia L. roots–a Comparative Study. Bull. Trans. Uni. Brasov. Series II: Forest., Wood Ind., Agricul. Food Engin. 2022; 15(64/2): 177-188.
Pérez-Cembranos A, Pérez-Mellado V. The effect of plant consumption in the overall diet of an omnivorous lizard. Salam. 2015;51(2): 63-72.
Strzemski M, Wójciak-Kosior M, Sowa I, Załuski D, Szwerc W, Sawicki J, Kocjan R, Feldo M, Dresler S. Carlina vulgaris L. as a source of phytochemicals with antioxidant activity. Oxid. Med. Cell Longev. 2017; 2017(1891849): 1-10.
Spinozzi E, Ferrati M, Cappellacci L, Caselli A, Perinelli DR, Bonacucina G, Maggi F, Strzemski M, Petrelli R, Pavela R, Desneux N. Carlina acaulis L. (Asteraceae): Biology, phytochemistry, and application as a promising source of effective green insecticides and acaricides. Ind. Crops Prod. 2023;192 (116076): 1–15.
Strzemski M, Płachno BJ, Mazurek B, Kozłowska W, Sowa I, Lustofin K, Załuski D, Rydzik Ł, Szczepanek D, Sawicki J, Wójciak M. Morphological, anatomical, and phytochemical studies of Carlina acaulis L. cypsela. Int. J. Mol. Sci. 2020; 21(23):1-18.
Benelli G, Pavela R, Petrelli R, Nzekoue FK, Cappellacci L, Lupidi G, Quassinti L, Bramucci M, Sut S, Dall’Acqua S, Canale A. Carlina oxide from Carlina acaulis root essential oil acts as a potent mosquito larvicide. Ind. Crops Prod. 2019;137:356-66.
Jaradat NA, Al-lahham S, Zaid AN, Hussein F, Issa L, Abualhasan MN, Hawash M, Yahya A, Shehadi O, Omair R, Mousa A. Carlina curetum plant phytoconstituents, enzymes inhibitory and cytotoxic activity on cervical epithelial carcinoma and colon cancer cell lines. Eur. J. Integr. Med. 2019;30(100933):1-9.
Cardinali F, Osimani A, Taccari M, Milanović V, Garofalo C, Clementi F, Polverigiani S, Zitti S, Raffaelli N, Mozzon M, Foligni R. Impact of thistle rennet from Carlina acanthifolia All. subsp. acanthifolia on bacterial diversity and dynamics of a specialty Italian raw ewes' milk cheese. Int. J. Food Microbiol. 2017; 255:7-16.
Cardinali F, Taccari M, Milanović V, Osimani A, Polverigiani S, Garofalo C, Foligni R, Mozzon M, Zitti S, Raffaelli N, Clementi F. Yeast and mould dynamics in Caciofiore della Sibilla cheese coagulated with an aqueous extract of Carlina acanthifolia All. Yeast. 2016;33(8):403-414.
Stoličná R. Possibilities of using wild plants in the traditional culinary culture of Slovakia. Slov. národ. 2016;64(2):241-250.
Eminov E., Saralieva E., Petrova Iv., Petkova N., Hadjikinova R., Ivanov I. Design of dark chocolate bonbons enriched with Carlina acanthifolia L. flour – physicochemical characterization and sensory analysis, Indust. Technol. 2022;9 (1):29-34.
Đorđević S, Tadić VA, Petrović S, Kukić-Marković J, Dobrić S, Milenković M, Hadžifejzović N. Bioactivity assays on Carlina acaulis and C. acanthifolia root and herb extracts. Dig. J. Nanomater. Biostructures. 2012;7(3):213-1222.
Fedoryshyn O, Zahorodnia D, Krvavych A, Mylyanych O, Petrina R. Development of technological scheme of Carlina acaulis root’s extraction. Sci. Bull. of UNFU. 2021;31(1):93-98. (in Ukrainian)
Saralieva E, Dincheva I, Tumbarski Y, Petkova N, Vilhelmova-Ilieva N, Nikolova I, Simeonova L, Ivanov I. Chemical composition, antibacterial, antiviral, antioxidant, and acetylcholinesterase inhibitory properties of essential oils from Carlina acanthifolia All. roots. J. Essent. Oil-Bear. Plants. 2022;25(5):976-986.
Strzemski, M., Wojciak-Kosior, ´ M., Sowa, I., Rutkowska, E., Szwerc, W., Kocjan, R., Latalski, M., Carlina species as a new source of bioactive pentacyclic triterpenes. Ind. Crop. Prod. 2016; 94:498–504.
Strzemski M, Wójciak-Kosior M, Sowa I, Załuski D, Szwerc W, Sawicki J, Kocjan R, Feldo M, Dresler S. Carlina vulgaris L. as a source of phytochemicals with antioxidant activity. Oxid. Med. Cell. Longev. 2017; 1891849: 1-11
.
Dorsaf H, Sabrine M, Zaineb BB, Olfa T, Mohsen S, Khémaïs BR. Reproductive toxicity of Carlina gummifera l. incense inhalation in adult male wistar rats. J. Hum. Reprod. Sci. 2022;15(1):12-20.
Ranjit R, Paudel S, Shrestha R, Maharjan J, Devi Devkota B, Bhattarai S, Prasad Pandey B. Biological and Chemical Analysis of Five Selected Lichen Species from Sagarmatha National Park of Nepal. Trop J Nat Prod Res. 2020; 4(2):43-48.
Rafi M, Febriany S, Wulandari P, Suparto IH, Ridwan T, Rahayu S, Siswoyo DM. Total phenolics, flavonoids, and anthocyanin contents of six vireya rhododendron from indonesia and evaluation of their antioxidant activities. J. App. Pharm. Sci. 2018;8(09):049-054.
Kristiningrum N, Amaliyah EA, Pratoko DK. Phytochemical screening, antioxidant and antibacterial activities of ethanol extract and fractions of Aleurites moluccana (L.) Willd. leaves. Trop. J. Nat. Prod. Res. 2020;4(11):895-898.
Mukhtar A, Abubakar A, G. Chukwubuike O. In-vitro antioxidant activities of different stem bark extracts of Irvingia gabonensis (Irvingiaceae). Trop. J. Nat. Prod. Res. 2020;4(6):223-227.
Ranjit R, Paudel S, Shrestha R, Maharjan J, Devi Devkota B, Bhattarai S, Prasad Pandey B. Biological and chemical analysis of five selected lichen species from Sagarmatha national park of Nepal. Trop. J Nat. Prod. Res. 2020;4(2):43-48.
Sherova G, Pavlov A, Georgiev V. Polyphenols profiles and antioxidant activities of extracts from Capsicum chinense in vitro plants and callus cultures. FSAB. 2019;2(1):30-37.
Vrancheva R, Ivanov I, Dincheva I, Badjakov I, Pavlov A. Triterpenoids and other non-polar compounds in leaves of wild and cultivated Vaccinium species. Plants. 2021;10(94):1-16
Petkova N., Ognyanov M. Phytochemical characteristics and in vitro antioxidant activity of fresh, dried and processed fruits of Cornelian cherries (Cornus mas L.). Bulg. Chem. Commun. 2018; 50 (C): 302-307.
Strzemski M, Wójciak-Kosior M, Sowa I, Agacka-Mołdoch M, Drączkowski P, Matosiuk D, Kurach Ł, Kocjan R, Dresler S. Application of Raman spectroscopy for direct analysis of Carlina acanthifolia subsp. utzka root essential oil. Tal. 2017;174:633-637.
Kaçar D. Screening of some plant species for their total antioxidant and antimicrobial activities (Doctoral dissertation, Izmir Institute of Technology (Turkey) Izmir, 2008. p.85
Sowa I, Mołdoch J, Dresler S, Kubrak T, Soluch A, Szczepanek D, Strzemski M, Paduch R, Wójciak M. Phytochemical profiling, antioxidant activity, and protective effect against H2O2-induced oxidative stress of Carlina vulgaris extract. Mol. 2023;28(14): 1-14.
Jović J, Mihajilov-Krstev T, Žabar A, Stojanović-Radić Z. Influence of solvent on antimicrobial activity of Carlinae radix essential oil and decoct. Biol. Nyssana. 2012;3(2):61-67.
Sörensen JS, Sörensen NA. Studies related to naturally occurring acetylene compounds. XIX. The isolation of 1-acetoxy-n-trideca-2: 10: 12-triene-4: 6: 8-triyne from Carlina vulgaris L. Acta Chem. Scand. 1954;8:1763-1768.
Belabbes R, Mami IR, Dib ME, Mejdoub K, Tabti B, Costa J, Muselli A. Chemical composition and biological activities of essential oils of Echinops spinosus and Carlina vulgaris rich in polyacetylene compounds. Curr. Nutr. Food Sci. 2020;16(4):563-570.
Pavela R, Maggi F, Petrelli R, Cappellacci L, Buccioni M, Palmieri A, Canale A, Benelli G. Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells. Food Chem. Toxicol. 2020;136(111037):1-7.
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Tropical Journal of Natural Product Research (TJNPR)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
