The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a neuropeptide
- Published
- Accepted
- Subject Areas
- Agricultural Science, Biochemistry, Entomology, Neuroscience, Zoology
- Keywords
- RT-PCR, PC1, immunohistology, SG-SASP, PC2, antiserum
- Copyright
- © 2017 Veenstra
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2017. The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a neuropeptide. PeerJ Preprints 5:e2940v1 https://doi.org/10.7287/peerj.preprints.2940v1
Abstract
A salivary gland salivation stimulating peptide was identified from the salivary glands of the migratory locust by its ability to stimulate cAMP production in the same tissue. The gene coding for this peptide has recently been shown to code for a precursor consisting of a signal peptide, several copies of the peptide separated by Lys-Arg doublets and a few other peptides. These data are consistent with it being a neuropeptide. However, antiserum raised to this peptide labels the acini of the salivary glands while RT-PCR only gives positive results in the salivary gland, but not in any ganglion of the central nervous system. Thus, this peptide is not a neuropeptide as previously assumed.
Author Comment
This is a submission to PeerJ for review.