The Synthesis of Uracils as Anticonvulsants

doi:10.1002/jps.3030440910

Journal of the American Pharmaceutical Association (Scientific ed.)

Volume 44, Issue 9, September 1955, Pages 545-550

https://doi.org/10.1002/jps.3030440910 Get rights and content

Abstract

A convenient laboratory synthesis has been devised by which a series of new 5‐alkyluracils has been prepared for evaluation as anti‐convulsants. Certain other 5‐substituted uracils and their N,N‐dimethyl derivatives, and related compounds, have also been synthesized. The anticonvulsant activity of uracil and thymine has been surpassed by several members of this new series.

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^*: Laboratory of Pharmaceutical Chemistry, University of Kansas School of Pharmacy, Lawrence

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ArticlesThe Synthesis of Uracils as Anticonvulsants*

Abstract

THIS JOURNAL

Organic Chemistry

Organic Chemistry

Helv. Chim. Acta

J. Am. Chem. Soc.

J. Am. Chem. Soc.

J. Am. Chem. Soc.

J. Am. Chem. Soc.

J. prakt. Chem.

J. Am. Chem. Soc.

Organic Syntheses

J. Am. Chem. Soc.

J. Am. Chem. Soc.

J. Am. Chem. Soc.

Articles
The Synthesis of Uracils as Anticonvulsants*