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Dutta J, Dutta PK, Rinki K et al (2008) Current research on chitin and chitosan for tissue engineering applications and future demands on bioproducts. In: Jayakumar R, Prabaharan M (eds) Current research and developments on chitin and chitosan in biomaterials science. Research Signpost, Trivandrum
Malafaya PB, Pedro AJ, Peterbauer A et al (2005) Chitosan particles agglomerated scaffolds for cartilage and osteochondral tissue engineering approaches with adipose tissue derived stem cells. J Mater Sci Mater Medicine 16:1077–1085
Glowacki J, Mizuno S (2008) Collagen scaffolds for tissue engineering. Biopolymers 89:338–344
Wang M, Chen LJ, Weng J et al (2001) Manufacture and evaluation of bioactive and biodegradable materials and scaffolds for tissue engineering. J Mater Sci Mater Med 12:855–860
Hoerstrup SP, Lu L, Lysaght MJ et al (2004) Tissue engineering. In: Ratner BD, Hoffman AS, Schoen FJ et al (eds) Biomaterial science. Elsevier Academic, San Diego
Langer R, Vacanti JP (1993) Tissue engineering. Science 260:920–926
Ehrenfreund-Kleinman T, Golenser J, Domb AJ (2006) Polysachharide scaffolds for tissue engineering. In: Ma PX, Elisseeff J (eds) Scaffolding in tissue engineering. CRC, Boca Raton
Jagur-Grodzinski J (2003) Biomedical applications of polymers. e-polymers 012
Thein-Han WW, Kitiyanant Y, Mishra RDK (2008) Chitosan as scaffold matrix for tissue engineering. Mater Sci Technol 24:1062–1075
Duarte ARC, Mano JF, Reis RL (2009) Perspectives on supercritical fluid technology for 3D tissue engineering scaffold applications. J Bioact Compat Polym 24:385–400
Whang K, Healy E, Elenz DR (1999) Engineering bone regeneration with bioabsorbable scaffolds with novel microarchitecture. Tissue Eng 5:35–51
Verma P, Verma V, Ray AR (2005) Chitin and chitosan: chitosan as tissue engineering scaffolds. In: Dutta PK (ed) Chitin and chitosan: opportunities and challenges. SSM International Publication, Midnapore, West Bengal
O'Brien FJ, Harley BA, Yannas IV et al (2004) Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds. Biomaterials 25:1077–1086
Rinki K, Dutta J, Dutta PK (2007) Chitosan based scaffolds for tissue engineering applications. Asian Chitin J 3:69–78
Yang S, Leong K-F, Du Z et al (2001) The design of scaffolds for use in tissue engineering Part I Traditional factors. Tissue Eng 7:679–689
Chang BS, Lee C-K, Hong K-S et al (2000) Osteoconduction at porous hydroxyapatite with various pore configurations. Biomaterials 21:1291–1298
Shor L, Guceri S, Wen X et al (2007) Fabrication of three-dimensional polycaprolactone/hydroxyapatite tissue scaffolds and osteoblast-scaffold interactions in vitro. Biomaterials 28:5291–5297
Wu L, Jing D, Ding JA (2006) “room-temperature” injection molding/particulate leaching approach for fabrication of biodegradable three-dimensional porous scaffolds. Biomaterials 27:185–191
Ingber D, Karp S, Plopper G et al (1993) Mechanochemical transduction across extracellular matrix and through the cytoskeleton. In: Frangos JA, Ives CL (eds) Physical forces and the mammalian cell. Academic, San Diego
Tessmar JKV, Holland TA, Mikos AG (2006) Salt leaching for polymer scaffolds: laboratory-scale manufacture of cell carriers. In: Ma PX, Elisseeff J (eds) Scaffolding in tissue engineering. CRC, Boca Raton
Murphy WL, Dennis RG, Kileny JL et al (2002) Salt fusion: an approach to improve pore interconnectivity within tissue engineering scaffolds. Tissue Eng 8:43–52
Wang AJ, Cao WL, Gong K et al (2006) Controlling morphology and porosity of 3-D chitosan scaffolds produced by thermally induced phase separation technique. Asian Chitin J 2:69–78
Leong KF, Cheah CM, Chua CK (2003) Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. Biomaterials 24:2363–2378
Sahai N (2010) Characterization of porous tissue scaffolds using computer aided tissue engineering. M Tech dissertation submitted to MNNIT, Allahabad
Partap S, Hebb AK, Rehman I et al (2007) Formation of porous natural-synthetic polymer composites using emulsion templating and supercritical fluid assisted impregnation. Polym Bull 58:849–860
Hu X, Lessery AJ (2006) Solid-state processing of polymer in the presence of supercritical carbon Dioxide. J Cell Plast 42:517–527
Rinki K, Dutta PK, Hunt AJ et al (2011) Chitosan aerogel exhibiting high surface area for biomedical applications: preparation, characterization and antibacterial study. Int J Polym Mater Article ID 553849 (GPOM-2010–0362.R1)
Sachlos E, Wahl DA, Triffitt JT et al (2008) The impact of critical point drying with liquid carbon dioxide on collagen-hydroxyapatite composite scaffolds. Acta Biomater 4:1322–1331
Rinki K, Dutta PK (2008) Preparation of genipin crosslinked chitosan scaffolds using supercritical carbon dioxide (sc. CO2). Asian Chitin J 4:43–48
Rinki K, Dutta PK, Hunt AJ et al (2009) Preparation of chitosan scaffolds using supercritical carbon dioxide. Macromol Symp 277:36–42
Wei X, Wang K, Chen J (2011) The functional inorganic composites. Prog Chem 23:42–52
Rinki K, Shipra T, Dutta PK et al (2009) Direct chitosan scaffold formation via chitin whiskers by a supercritical carbon dioxide method: a green approach. J Mater Chem 19:8651–8655
Rinki K, Dutta PK (2010) Chitosan based scaffolds by lyophilization and sc. CO2 assisted methods for tissue engineering applications: a benign green chemistry approach. J Macromol Sci Pure Appl Chem A47:429–434
Rinki K, Dutta PK (2010) Physicochemical and biological activity study of genipin-crosslinked chitosan scaffolds prepared by using supercritical carbon dioxide for tissue engineering applications. Int J Biol Macromol 46:261–266
Jayakumar R, Prabaharan M, Nair SV et al (2010) Novel chitin and chitosan nanofibers in biomedical applications. Biotechnol Adv 28:142–150
Li W-J, Laurencin CT, Caterson EJ et al (2002) Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res 60:613–621
Mo X, Chen Z, Hans JW (2007) Electrospun nanofibers of collagen-chitosan and P(LLA-CL) for tissue engineering. Front Mater Sci China 1:20–23
Kharande TS, Agrawal CM (2008) Functions and requirements of synthetic scaffolds in tissue engineering. In: Laurencin CT, Nair LS (eds) Nanotechnology and tissue engineering: the scaffold. CRC, Boca Raton
Kang YM, Lee BN, Ko JH et al (2010) In vivo biocompatibility study of electrospun chitosan microfiber for tissue engineering. Int J Mol Sci 11:4140–4148
Pillai CKS, Chandra PS (2009) Electrospinning of chitin and chitosan nanofibres. Trends Biomater Artif Organs 22:175–197
Liang D, Hsiao BS, Chu B (2007) Functional electrospun nanofibrous scaffolds for biomedical applications. Adv Drug Deliv Rev 59:1392–1412
Jia Y-T, Gong J, Xiao-Hua Gu et al (2007) Fabrication and characterization of poly (vinyl alcohol)/chitosan blend nanofibers produced by electrospinning method. Carbohydr Polym 67:403–409
Duan B, Yuan X, Zhu Y et al (2006) A nanofibrous composite membrane of PLGA–chitosan/PVA prepared by electrospinning. Eur Polym J 42:2013–2022
Chupa JM, Foster AM, Sumner SR et al (2000) Vascular cell responses to polysaccharide materials: in vitro and in vivo evaluations. Biomaterials 21:2315–2322
Dutta PK, Tripathi S, Mehrotra GK et al (2009) Perspectives for chitosan based antimicrobial films for food applications. Food Chem 114:1173–1182
Dutta PK, Dutta J, Tripathi VS (2004) Chitin and chitosan: Chemistry, properties and applications. J Sci Ind Res 63:20–31
Dutta PK, Dutta J, Chattopadhyaya MC et al (2004) Chitin and chitosan: novel biomaterials waiting for future developments. J Polym Mater 21:321–334
Venkatesan J, Kim SK (2010) Chitosan composites for bone tissue engineering – an overview. Mar Drugs 8:2252–2266
Muzzarelli RAA (1993) Biochemical significance of exogenous chitins and chitosans in animals and patients. Carbohydr Polym 20:7–16
Archana D, Dutta J, Dutta PK (2010) Chitosan-pectin-titanium dioxide nano-composite film: an investigation for wound healing applications. Asian Chitin J 6:45–46
Seal BL, Otero TC, Panitch A (2001) Polymeric biomaterials for tissue and organ regeneration. Mater Sci Eng Res 34:147–230
Hasirci V, Lewandrowski K, Gresser JD et al (2001) Versatility of biodegradable biopolymers: degradability and an in vivo application. J Biotechnol 86:135–150
Marler JJ, Upton J, Langer R et al (1998) Transplantation of cells in matrices for tissue regeneration. Adv Drug Deliv Rev 33:165–182
Muzzarelli C, Muzzarelli RAA (2002) Natural and artificial chitosan-inorganic composites. J Inorg Biochem 92:89–94
Khor E, Lim LY (2003) Implantable applications of chitin and chitosan. Biomaterials 24:2339–2349
Mi FL, Shyu SS, Wu YB et al (2001) Fabrication and characterization of a sponge-like asymmetric chitosan membrane as a wound dressing. Biomaterials 22:165–173
Jayakumar R, Divyarani VV, Shalumon KT et al (2009) Development of novel α- and β-chitin hydrogel membranes for tissue engineering applications. Asian Chitin J 5:63–70
Jiang T, Nair LS, Laurencen CT (2006) Chitosan composites for tissue engineering: bone tissue engineering scaffolds. Asian Chitin J 2:1–10
Li J, Pan J, Zhang L, Yu Y (2003) Culture of hepatocytes on fructose-modified chitosan scaffolds. Biomaterials 24:2317–2322
Enescu D, Olteanu CE (2008) Functional chitosan and its use in pharmaceutical, biomedical, and biotechnological research. Chem Eng Commun 195:1269–1291
Wu T, Zivanovic S, Draughon FA et al (2005) Physicochemical properties and bioactivity of fungal chitin and chitosan. J Agric Food Chem 53:3888–3894
Dutta PK, Singh J (2008) Conformational study of chitosan: a review. Proceedings of the National Academy of Sciences India Part IV LXXVIII:255–270
Tomihata K, Ikada Y (1997) In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. Biomaterials 18:567–575
Shigemasa Y, Saito K, Sashiwa H et al (1994) Enzymatic degradation of chitins and partially deacetylated chitins. Int J Biol Macromol 16:43–49
Hutadilok N, Mochimasu T, Hisamori H et al (1995) The effect of N-substitution on the hydrolysis of chitosan by an endo-chitosanase. Carbohydr Res 268:143–149
Nordtveit RJ, Varum KM, Smidsrod O (1996) The effect of N-substitution on the hydrolysis of chitosan by an endo-chitosanase. Carbohydr Polym 29:163–167
Varum KM, Myhr MM, Hjerde RJ et al (1997) In vitro degradation rates of partially N-acetylated chitosans in human serum. Carbohydr Res 299:99–101
Zhang K, Qian Y, Wang H et al (2010) Genipin-crosslinked silk fibroin/hydroxybutyl chitosan nanofibrous scaffolds for tissue-engineering application. J Biomed Mater Res 95A:870–881
Sathirakul K, How NC, Stevens WF et al (1996) Application of chitin and chitosan bandages for wound-healing. In: Domard A, Jeauniaux C, Muzzarelli R, Roberts G (eds) Proceedings of the first international conference of the European Chitin Society. Advances in chitin science, vol 1. Jacques Andre Publisher, Lyon
Hidaka Y, Ito M, Mori K et al (1999) Histopathological and immunohistochemical studies of membranes of deacetylated chitin derivatives implanted over rat calvaria. J Biomed Mater Res 46:418–423
Hsu S, Whu SW, Tsai C et al (2004) Chitosan as scaffold materials: effects of molecular weight and degree of deacetylation. J Polym Res 11:141–147
Chatelet C, Damour O, Domard A (2001) Infuence of the degree of acetylation on some biological properties of chitosan films. Biomaterials 22:261–268
Kim I-Y, Seo S-J, Moon H-S et al (2008) Chitosan and its derivatives for tissue engineering applications. Biotechnol Adv 26:1–21
Chen GP, Sato T, Ohgushi H et al (2005) Culturing of skin fibroblasts in a thin PLGA-collagen hybrid mesh. Biomaterials 26:2559–2566
Ma L, Gao CY, Mao ZW et al (2003) Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering. Biomaterials 24:4833–4841
Khnor E, Lim L (2003) Implantated applications of chitin and chitosan. Biomaterials 24:2339–2349
Ueno H, Mori T, Fujinaga T (2001) Topical formulations and wound healing applications of chitosan. Adv Drug Deliv Rev 52:105–115
Radhika M, Mary B, Sehgal PK (1999) Cellular proliferation on desamidated collagen matrices. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 124:131–139
Archana D, Dutta J, Dutta PK (2010) Synthesis, characterization and bioactivity with improved antibacterial effect of chitosan-pectin-titanium dioxide ternary film for biomedical applications. Asian Chitin J 6:26
Adekogbe I, Ghanem A (2005) Fabrication and characterization of DTBP-crosslinked chitosan scaffolds for skin tissue engineering. Biomaterials 26:7241–7250
Liu H, Fan H, Cui Y et al (2007) Effects of the controlled-released basic fibroblast growth factor from chitosan-gelatin microspheres on a chitosan-gelatin scaffold. Biomacromolecules 8:1446–1455
Powell HM, Boyce ST (2006) EDC cross-linking improves skin substitute strength and stability. Biomaterials 27:5821–5827
Dhandayuthapani B, Krishnan UM, Sethuraman S (2010) Fabrication and characterization of chitosan-gelatin blend nanofibers for skin tissue engineering. J Biomed Mater Res 94B:264–272
Lu G, Wang G, Sheng B et al (2008) Bimodal carboxymethyl chitosan/collagen nanofiber composite scaffolds for bone tissue engineering. Asian Chitin J 4:49–58
Service RF (2000) Tissue engineers build new bone. Science 289:1498–1500
Petite H, Viateau V, Bensaid W et al (2000) Tissue-engineered bone regeneration. Nat Biotechnol 18:959–963
Muzzarelli RAA (2009) Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone. Carbohydr Polym 76:167–182
Martins AM, Alves CM, Kasper FK et al (2010) Responsive and in situ-forming chitosan scaffolds for bone tissue engineering applications: an overview of the last decade. J Mater Chem 20:1638–1645
Li Z, Ramay HR, Hauch KD et al (2005) Chitosan–alginate hybrid scaffolds for bone tissue engineering. Biomaterials 26:3919–3928
Manjubala I, Ponomarev I, Jandt KD et al (2004) Adhesion and proliferation of osteoblastic cells seeded on chitosan-hydroxyapatite porous scaffold. Eur Cell Mater 7:64
Zhang Y, Ni M, Zhang M et al (2003) Calcium phosphate-chitosan composite scaffolds for bone tissue engineering. Tissue Eng 9:337–345
Jiang T, Abdel-Fattah WI, Laurencin CT (2006) In vitro evaluation of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds for bone tissue engineering. Biomaterials 27:4894–4903
Xu HHK, Simon CG Jr (2005) Fast setting calcium phosphate-chitosan scaffold: mechanical properties and biocompatibility. Biomaterials 26:1337–1348
Kuo Y, Lin C (2006) Effect of genipin-crosslinked chitin-chitosan scaffolds with hydroxyapatite modifications on the cultivation of bovine knee chondrocytes. Biotechnol Bioeng 95:132–144
Yan LP, Wang YJ, Wu G et al (2010) Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications. J Biomed Mater Res 95A:465–475
Kong L, Gao Y, Lu G et al (2006) A study on the bioactivity of chitosan/nano-hydroxyapatite composite scaffolds for bone tissue engineering. Eur Polym J 42:3171–3179
Sailaja GS, Ramesh P, Kumary TV et al (2006) Human osteosarcoma cell adhesion behaviour on hydroxyapatite integrated chitosan–poly(acrylic acid) polyelectrolyte complex. Acta Biomater 2:651–657
Manjubala I, Ponomarev I, Wilke I et al (2008) Growth of osteoblast-like cells on biomimetic apatite-coated chitosan scaffolds. J Biomed Mater Res Appl Biomater 84B:7–16
Sendemir-Urkmez A, Jamison RD (2006) The addition of biphasic calcium phosphate to porous chitosan scaffolds enhances bone tissue development in vitro. J Biomed Mater Res 81A:624–633
Lee E, Shin D, Kim H et al (2009) Membrane of hybrid chitosan–silica xerogel for guided bone regeneration. Biomaterials 30:743–750
Lee JE, Jeong MH, Ahn HJ et al (2005) Evaluation of chondrogenesis in collagen/chitosan/glycosaminoglycan scaffolds for cartilage tissue engineering. Tissue Eng Regenerative Medicine 2:41–49
Yamane S, Iwasaki N, Majima T et al (2005) Feasibility of chitosan-based hyaluronic acid hybrid biomaterial for a novel scaffold in cartilage tissue engineering. Biomaterials 26:611–619
Chen YL, Lee HP, Chan HY et al (2007) Composite chondroitin-6-sulfate/dermatan sulphate/chitosan scaffolds for cartilage tissue engineering. Biomaterials 28:2294–2305
Wu H, Wan Y, Cao X et al (2008) Proliferation of chondrocytes on porous poly(DL-lactide)/chitosan scaffolds. Acta Biomater 4:76–87
Lao L, Tan H, Wang Y et al (2008) Chitosan modified poly(l-lactide) microspheres as cell microcarriers for cartilage tissue engineering. Colloids Surf B Biointerfaces 66:218–225
Tan H, Wu J, Lao L (2009) Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineering. Acta Biomater 5:328–337
Putnam AJ, Mooney DJ (1996) Tissue engineering using synthetic extracellular matrices. Nat Med 2:824–826
Smentana K (1993) Cell biology of hydrogels. Biomaterials 14:1046–1050
Cohen S, Glicklis R, Shapiro L et al (2000) Hepatocyte behavior within three-dimensional porous alginate scaffolds. Biotechnol Bioeng 67:344–353
Yang J, Chung TW, Nagaoka M et al (2001) Hepatocyte-specific porous polymer-scaffolds of alginate/galactosylated chitosan sponge for liver-tissue engineering. Biotechnol Lett 23:1385–1389
Chung TW, Yang J, Akaike T et al (2002) Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment. Biomaterials 23:2827–2834
Seglen PO (1972) Preparation of rat liver cells. Exp Cell Res 74:450–454
Li J, Pan J, Zhang L et al (2003) Culture of hepatocytes on fructose-modified chitosan scaffolds. Biomaterials 24:2317–2322
Park IK, Yang J, Jeong HW et al (2003) Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment. Biomaterials 24:2331–2337
Wang XH, Li DP, Wang WJ et al (2003) Crosslinked collagen/chitosan matrix for artificial livers. Biomaterials 24:3213–3220
Jiankang H, Dichen L, Yaxiong L et al (2009) Preparation of chitosan–gelatin hybrid scaffolds with well-organized microstructures for hepatic tissue engineering. Acta Biomater 5:453–461
Feng ZQ, Chu X, Huang NP et al (2009) The effect of nanofibrous galactosylated chitosan scaffolds on the formation of rat primary hepatocyte aggregates and the maintenance of liver function. Biomaterials 30:2753–2763
Sivakumar R, Rajesh R, Buddhan S et al (2007) Antilipidemic effect of chitosan against experimentally induced myocardial infarction in rats. J Cell Animal Biol 1:71–77
Wei HJ, Chen CH, Lee WY et al (2008) Bioengineered cardiac patch constructed from multilayered mesenchymal stem cells for myocardial repair. Biomaterials 29:3547–3556
Perin EC, Dohmann HF, Borojevic R et al (2003) Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation 107:2294–2302
Park H, Radisic M, Lim JO et al (2005) A novel composite scaffold for cardiac tissue engineering. In Vitro Cell Dev Biol – Animal 41:188–196
Freed LE, Vunjak-Novakovic G (2000) Tissue engineering bioreactors. In: Lanza RP, Langer R, Vacanti JP (eds) Principles of tissue engineering, 2nd edn. Academic, San Diego
Radisic M, Obradovic B, Vunjak-Novakovic G (2006) Functional tissue engineering of cartilage and myocardium: bioreactor aspects. In: Ma PX, Elisseeff J (eds) Scaffolding in tissue engineering. CRC, Boca Raton
Birla RK, Dow DE, Huang YC et al (2008) Methodology for the formation of functional, cell-based cardiac pressure generation constructs in vitro. In Vitro Cell Dev Biol – Animal 44:340–350
Blan NR, Birla RK (2008) Design and fabrication of heart muscle using scaffold-based tissue engineering. J Biomed Mater Res 86A:195–208
Cuy JL, Beckstead BL, Brown CD et al (2003) Adhesive protein interactions with chitosan: consequences for valve tissue-engineering. J Biomed Mater Res 67A:538–547
Liu L, Guo S, Chang J et al (2008) Surface Modification of polycaprolactone membrane via layer-by-layer deposition for promoting blood compatibility. J Biomed Mater Res Appl Biomater 87B:244–250
Zhu C, Fan D, Duan Z et al (2009) Initial investigation of novel human-like collagen/chitosan scaffold for vascular tissue engineering. J Biomed Mater Res 89A:829–840
Zhang L, Ao Q, Wang A et al (2006) A sandwich tubular scaffold derived from chitosan for blood vessel tissue engineering. J Biomed Mater Res 77A:277–284
He Q, Ao Q, Gong K et al (2010) Preparation and characterization of chitosan-heparin composite matrices for blood contacting tissue engineering. Biomed Mater 5:055001
Kalayoglu MV. In search of the artificial cornea: recent developments in keratoprostheses. http://www.medcompare.com/spotlight.asp?spotlightid=159
Wang Y, Guo L, Ren L et al (2009) A study on the performance of hyaluronic acid immobilized chitosan film. Biomed Mater 4:1–7
Gao X, Liu W, Han B et al (2008) Preparation and properties of a chitosan-based carrier of corneal endothelial cells. J Mater Sci Mater Med 19:3611–3619
Du LQ, Wu XY, Li MC et al (2008) Effect of different biomedical membranes on alkali-burned cornea. Ophthalmic Res 40:282–290
Chen J, Li Q, Xu J et al (2005) Study on biocompatibility of complexes of collagen–chitosan–sodium hyaluronate and cornea. Artif Organs 29:104–113
Rafat M, Li F, Fagerholm P et al (2008) PEG-stabilized carbodiimide crosslinked collagen–chitosan hydrogels for corneal tissue engineering. Biomaterials 29:3960–3972
Zielinski BA, Aebischer P (1991) Chitosan as a matrix for mammalian cell encapsulation. Biomaterials 15:1049–1056
Dillon GP, Yu X, Sridharan A et al (1998) The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold. J Biomater Sci Polym Edn 9:1049–1069
Dillon GP, Yu X, Bellamkonda RV (2000) The polarity and magnitude of ambient charge influences three-dimensional neurite extension from DRGs. J Biomed Mater Res 51A:510–519
Gong H, Zhong Y, Li J et al (2000) Studies on nerve cell affinity of chitosan-derived materials. J Biomed Mater Res 52A:285–295
Cheng M, Cao W, Gao Y et al (2003) Studies on nerve cell affinity of biodegradable modified chitosan films. J Biomater Sci Polym Edn 14:1155–1167
Midha R, Shoichet MS, Dalton PD et al (2001) Tissue engineered alternatives to nerve transplantation for repair of peripheral nervous system injuries. Transplant Proc 33:612
Keilhoff G, Stang F, Wolf G et al (2003) Bio-compatibility of type I/III collagen matrix for peripheral nerve reconstruction. Biomaterials 24:2779–2787
Ashtona RS, Banerjee A, Punyania S et al (2007) Scaffolds based on degradable alginate hydrogels and poly(lactide-co-glycolide) microspheres for stem cell culture. Biomaterials 28:5518–5525
Scanga VI, Goraltchouk A, Nussaiba N et al (2010) Biomaterials for neural-tissue engineering- chitosan supports the survival, migration, and differentiation of adult-derived neural stem and progenitor cells. Can J Chem 88:277–287
Frier T, Montenegro KHS et al (2005) Chitin-based tubes for tissue engineering in the nervous system. Biomaterials 26:4624–4632
Thein-Han WW, Kitiyanant Y (2007) Chitosan scaffolds for in vitro buffalo embryonic stem-like cell culture: an approach to tissue engineering. J Biomed Mater Res Appl Biomater 80B:92–101
Prabhakaran MP, Venugopal JR, Chyan TT et al (2008) Electrospun biocomposite nanofibrous scaffolds for neural tissue engineering. Tissue Eng 14:1787–1797
Wang AJ, Cao WL, Gong K et al (2006) Development of porous chitosan tubular scaffolds for tissue engineering applications. Asian Chitin J 2:53–60
Frier T, Koha HS, Kazaziana K et al (2005) Controlling cell adhesion and degradation of chitosan films by N-acetylation. Biomaterials 26:5872–5878
Xiangmei W, Jing Z, Hao C et al (2009) Preparation and characterization of collagen-based composite conduit for peripheral nerve regeneration. J Appl Polymer Sci 112:3652–3662
Ishikawa N, Suzuki Y, Dezawa M et al (2009) Peripheral nerve regeneration by transplantation of BMSC-derived Schwann cells. J Biomed mater Res 89A:1118–1124
Ishikawa N, Suzuki Y, Ohta M et al (2007) Peripheral nerve regeneration through the space formed by a chitosan gel sponge. J Biomed Mater Res 83A:33–40
Peng L, Cheng XR, Wang JW et al (2006) Preparation and evaluation of porous chitosan/collagen scaffolds for periodontal tissue engineering. J Bioactive Compatible Polym 21:207–220
Zhang Y, Song J, Shi B et al (2007) Combination of scaffold and adenovirus vectors expressing bone morphogenetic protein-7 for alveolar bone regeneration at dental implant defects. Biomaterials 28:4635–4642
Shao X, Hunter CJ (2007) Developing an alginate/chitosan hybrid fiber scaffold for annulus fibrous cells. J Biomed Mater Res 82A:701–710
Acknowledgments
Authors gratefully acknowledged the financial assistance to KR in the form of Institute Research Fellowship from MNNIT, Allahabad and research funding to PKD from UGC, New Delhi. The RSC (London) -Research Fund Grant Award-2009 to PKD is also gratefully acknowledged.
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Dutta, P.K., Rinki, K., Dutta, J. (2011). Chitosan: A Promising Biomaterial for Tissue Engineering Scaffolds. In: Jayakumar, R., Prabaharan, M., Muzzarelli, R. (eds) Chitosan for Biomaterials II. Advances in Polymer Science, vol 244. Springer, Berlin, Heidelberg. https://doi.org/10.1007/12_2011_112
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