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Biological Activity of Aminophosphonic Acids and Their Short Peptides

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Phosphorous Heterocycles I

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 20))

Abstract

The biological activity and natural occurrence of the aminophosphonic acids were described half a century ago. Since then the chemistry and biology of this class of compounds have developed into the separate field of phosphorus chemistry. Today it is well acknowledged that these compounds possess a wide variety of promising, and in some cases commercially useful, physiological activities. Thus, they have found applications ranging from agrochemical (with the herbicides glyphosate and bialaphos being the most prominent examples) to medicinal (with the potent antihypertensive fosinopril and antiosteoporetic bisphosphonates being examples).

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References

  1. Horiguchi M, Kandatsu M (1959) Nature 184:901

    CAS  Google Scholar 

  2. Mastalerz P (1959) Archiv Immun Ter Dosw 7(20):1. Chem Abst 53:18879b

    Google Scholar 

  3. Chavane V (1949) Gen Ann Chim 4:352. Chem Abst 45:7516g

    Google Scholar 

  4. Franz JE, Mao MK, Sikorski JA (1997) Glyphosate:a unique global herbicide. Monograph 189. American Chemical Society, Washington DC

    Google Scholar 

  5. Okuhara M, Kuroda Y, Goto T, Okamoto M, Terano H, Kohsaka M, Aoki H, Imanaka H (1980) J Antibiot 33:13

    CAS  Google Scholar 

  6. Allen JG, Atherton FR, Hall MJ, Hassall CH, Holmes SW, Lambert RW, Nisbet LJ, Ringrose PS (1978) Nature 272:56

    CAS  Google Scholar 

  7. Karanewsky DS, Badia MC, Cushman DW, De Forrest JM, Dejneka T, Loots MJ, Pern MG, Petrillo Jr RD, Powell RJ (1988) J Med Chem 31:204

    CAS  Google Scholar 

  8. Russell RGG (2006) Ann NY Acad Sci 1068:367–401

    CAS  Google Scholar 

  9. Kukhar VP, Hudson HR (eds) (2000) Aminophosphonic and aminophosphinic acids: chemistry and biological activity. Wiley, Chichester

    Google Scholar 

  10. Kafarski P, Lejczak B (1991) Phosphorus Sulfur Silicon 63:193

    CAS  Google Scholar 

  11. Collinsova M, Jiracek J (2000) Curr Med Chem 7:629

    CAS  Google Scholar 

  12. Kafarski P, Lejczak B (2001) Curr Med Chem – Anti-Cancer Agents 1:301

    CAS  Google Scholar 

  13. Berlicki L, Kafarski P (2005) Curr Org Chem 9:1829

    CAS  Google Scholar 

  14. Romanenko VD, Kukhar VP (2006) Chem Rev 106:3868

    CAS  Google Scholar 

  15. Wardle NJ, Bligh SWA, Hudson HR (2007) Curr Org Chem 11:1635

    CAS  Google Scholar 

  16. Hecker SJ, Erion MD (2008) J Med Chem 51:2328

    CAS  Google Scholar 

  17. Macciarulo A, Pellicciari R (2007) J Mol Graph Model 26:728

    Google Scholar 

  18. Dingledine R, Borges K, Bowie D, Traynelis SF (1999) Pharmacol Rev 51:7

    CAS  Google Scholar 

  19. Selvam C, Goudet C, Ouselatti N, Pin J-P, Acher FC (2007) J Med Chem 50:4656

    CAS  Google Scholar 

  20. Tikhonova IG, Baskin II, Palyulin VA, Zefirov NS, Bachurin SO (2002) J Med Chem 45:3836

    CAS  Google Scholar 

  21. Grazioso G, Moretti L, Scapozza L, de Amici M, de Micheli C (2005) J Med Chem 48:5489

    CAS  Google Scholar 

  22. Schoepp DD, Jane DE, Monn JA (1999) Neuropharmacology 38:1431

    CAS  Google Scholar 

  23. Baudy RB, Fletcher III H, Yardley JP, Zaleska MM, Bramlett RD, Tasse RP, Kowal DM (2001) J Med Chem 44:1516

    CAS  Google Scholar 

  24. Brandt MR, Cummons TA, Potestio L, Sukoff SJ, Rozenzweig-Lipson S (2005) J Pharm Exp Ther 313:1379

    CAS  Google Scholar 

  25. Feng B, Morley RM, Jane DE, Monaghan DT (2005) Neuropharm 48:354

    CAS  Google Scholar 

  26. Filosa R, Marinozzi M, Constantino G, Hermit MB, Thomsen C, Pellicciari R (2006) Bioorg Med Chem 14:3811

    CAS  Google Scholar 

  27. Amori L, Constantino G, Marinozzi M, Pellicciari R, Gasparini F, Flor PJ, Kuhn R, Vranesic I (2000) Bioorg Med Chem Lett 10:1447

    CAS  Google Scholar 

  28. Bettler B, Kaupman K, Mosbacher J, Gassman M (2004) Physiol Rev 84:835

    CAS  Google Scholar 

  29. Ong J, Kerr DIB (2005) CNS Drug Rev 11:317

    CAS  Google Scholar 

  30. Bon C, Galvan M (1996) Brit J Pharmacol 118:961–967

    CAS  Google Scholar 

  31. Alstermark C, Amin K, Dinn SR, Elbering T, Fjellström O, Fitzpatrick K, Geiss WB, Gottfries J, Guzzo PR, Harding JP, Holmén A, Kothare M, Lehmann A, Mattsson JP, Nilsson K, Sundén G, Swanson M, von Unge S, Woo AM, Wyle MJ, Zheng X (2008) J Med Chem 51:4315

    CAS  Google Scholar 

  32. Kerr DI, Ong J, Prager RH, Gynther BD, Curtis GR (1987) Brain Res 495:150

    Google Scholar 

  33. Bowery NG, Enna SJ (2000) J Pharmacol Exp Ther 292:2

    CAS  Google Scholar 

  34. Murata Y, Woodward RM, Miledi R, Overmann LE (1996) Bioorg Med Chem Lett 6:2073

    CAS  Google Scholar 

  35. Krehan D, Frolund B, Krogsgaard-Larsen P, Kehler J, Johnston GAR, Chebib M (2003) Neurochem Int 42:561

    CAS  Google Scholar 

  36. Orain D, Mattes H (2006) Tetrahedron Lett 47:1253

    CAS  Google Scholar 

  37. Hinton T Chebib M, Johnston GAR (2008) Bioorg Med Chem Lett 18:402

    Google Scholar 

  38. Bertaccini E, Trudel JR (2001) Int Rev Neurobiol 48:141

    CAS  Google Scholar 

  39. Bowery NG, Bettler B, Froestl W, Gallagher JP, Marshall F, Raiteri M, Bonner TI, Enna SJ (2003) 54:247

    Google Scholar 

  40. Li X, Cao J-H, Li Y, Ronard P, Zhang Y, Yi P, Liu J-F, Nan F-J (2008) J Med Chem 51:3057

    Google Scholar 

  41. Iron A, Monique R, Duboy J-P, Beranger M, Cassaigne A, Neuzil E (1981) Biochem Soc Trans 9:246

    CAS  Google Scholar 

  42. Lejczak B, Kafarski P, Makowiecka E (1987) Biochem J 242:81

    CAS  Google Scholar 

  43. Gasowska B, Wojtasek H, Jurek J, Drag M, Nowak K, Kafarski P (2002) Eur J Biochem 269:4098

    CAS  Google Scholar 

  44. Evsigneeva ZG, Solovieva NA, Sidelnikova LI (2003) Prikl Biokhim Mikrobiol 39:613

    Google Scholar 

  45. Berlicki L (2008) Mini Rev Med Chem 8:869

    CAS  Google Scholar 

  46. Logusch EW, Walker DM, McDonald JF, Franz JE (1989) Biochemistry 29:3034

    Google Scholar 

  47. Gill HS, Eisenberg D (2001) Biochemistry 40:1903

    CAS  Google Scholar 

  48. Krajewski WW, Jones AT, Mowbray SL (2005) Proc Natl Acad Sci USA 102:10499

    CAS  Google Scholar 

  49. Berlicki L, Obojska A, Forlani G, Kafarski P (2006) J Med Chem 48:6340

    Google Scholar 

  50. Forlani G, Obojska A, Berlicki L, Kafarski P (2006) J Agric Food Chem 54:796

    CAS  Google Scholar 

  51. Nordqvist A, Nilsson MT, Röttger S, Odeli LR, Krajewski WW, Andersson CE, Larhed M, Mowbray SL, Karlen A (2008) Bioorg Med Chem 16:5501

    CAS  Google Scholar 

  52. Zon J, Amrhein N (1992) Liebigs Ann Chem 625

    Google Scholar 

  53. Appert C, Zon J, Amrhein N (2003) Phytochemistry 62:415

    CAS  Google Scholar 

  54. Zon J, Szefczyk B, Sawka-Dobrowolska W, Gancarz R, Kucharska-Zon M, Latajka R, Amrhein N, Miziak P, Szczepanik W (2004) New J Chem 28:1048

    CAS  Google Scholar 

  55. Zon J. Miziak P, Amrhein N, Gancarz R (2005) Chem Biodiv 2:1187

    CAS  Google Scholar 

  56. Miziak P, Zon J, Amrhein N, Gancarz R (2007) Phytochemistry 68:407

    CAS  Google Scholar 

  57. Shie J-J, Fang J-M, Wang S-Y, Tsai K-C, Cheng Y-SE, Yang A-S, Hsiao S-C, Su C-Y, Wong C-H (2007) J Am Chem Soc 129:11892

    CAS  Google Scholar 

  58. Steere JA, Sampson PB, Honek JF (2002) Bioorg Med Chem Lett 12:457

    CAS  Google Scholar 

  59. Giannousis PP, Bartlett PA (1987) J Med Chem 30:1603

    CAS  Google Scholar 

  60. Lejczak B, Kafarski P, Zygmunt J (1989) Biochemistry 28:3549

    CAS  Google Scholar 

  61. Kim H, Lipscomb WN (1994) Adv Enzymol Relat Areas Mol Biol 68:153

    CAS  Google Scholar 

  62. Strater N, Lipscomb WN (1995) Biochemistry 34:9200

    CAS  Google Scholar 

  63. Grembecka J, Sokalski WA, Kafarski P (2000) J Comput-Aided Mol Design 14:531

    CAS  Google Scholar 

  64. Grembecka J, Sokalski WA, Kafarski P (2001) Int J Quant Chem 84:302

    CAS  Google Scholar 

  65. Grembecka J, Mucha A, Cierpicki T, Kafarski P (2003) J Med Chem 46:2641

    CAS  Google Scholar 

  66. Zhang Z-Y (2002) Ann Rev Pharmacol Toxicol 42:202

    Google Scholar 

  67. Tautz L, Pellechia M, Mustelin T (2006) Exp Opin Therapeut Agents 10:157

    CAS  Google Scholar 

  68. Burke Jr TR (2006) Curr Top Med Chem 6:1465

    Google Scholar 

  69. Oishi S, Karki RG, Shi Z-D, Worthy KM, Bindu L, Chertov O, Esposito D, Frank P, Gilette WK, Maderia M, Hatley J, Nicklaus MC, Barchi Jr JJ, Fisher RJ, Burke Jr TR (2005) Bioorg Med Chem 13:2431

    CAS  Google Scholar 

  70. Boutselis IG, Yu XS, Zhang Z-Y, Borch RF (2007) J Med Chem 50:856

    CAS  Google Scholar 

  71. Dourlat J, Valentin B, Liu W-Q, Garbay C (2007) Bioorg Med Che. Lett 17:3943

    CAS  Google Scholar 

  72. Shen K (2007) Methods 42:234

    CAS  Google Scholar 

  73. Johnson TO, Ermolieff J, Jarousek MR (2002) Nat Drug Discovery 1:696

    CAS  Google Scholar 

  74. Kumar S, Zhou B, Liang F, Wang W-Q, Huang Z, Zhang Z-Y (2004) Proc Natl Acad Sci USA 101:7943–7948

    CAS  Google Scholar 

  75. Walchi S, Espanel X, Harrenga A, Rossi M, Cesareni G, van Huijduijnen (2004) J Biol Chem 279:311–318

    Google Scholar 

  76. Santos WL, Heasly BH, Jarosz R, Carter KM, Lynch KR, Macdonald TL (2004) Bioorg Med Chem Lett 14:3473

    CAS  Google Scholar 

  77. Hale JJ, Doherty G, Toth L, Mills SG, Hajdu R, Keohane CA, Rosenbach M, Milligan J, Shei G-J, Chrebet G, Bergstrom J, Card D, Forrest M, Sun S-Y, West S, Xie H, Nomura N, Rosen H, Mandala S (2004) Bioorg Med Chem Lett 14:3501

    CAS  Google Scholar 

  78. Foss Jr FW, Snyder AH, Davis MD, Rouse M, Okusa MD, Lynch KR, Macdonald TL (2007) Bioorg Med Chem 15:663

    Google Scholar 

  79. Cui P, Tomsig JL, McCalmont WF, Lee S, Becker CJ, Lynch KR, Macdonald TL (2007) Bioorg Med Chem Lett 17:1634

    CAS  Google Scholar 

  80. Cui P, McCalmont WF, Tomsig JL, Lynch KR, Macdonald TL (2008) Bioorg Med Chem 16:2212

    CAS  Google Scholar 

  81. Hakogi T, Yamamoto T, Fujii S, Ikeda K, Katsumura S (2006) Tetrahedron Lett 47:2627

    CAS  Google Scholar 

  82. Cox RJ, Gibson JS, Hadfield AT (2005) Chem BioChem 2255

    Google Scholar 

  83. Balg C, Blais SP, Bernier S, Hout JL, Couture M, Lapointe J, Chênevert R (2007) Bioorg Med Chem 15:295

    CAS  Google Scholar 

  84. Notter RH, Wang Z, Wang Z, Davy AD, Schwan AL (2007) Bioorg Med Chem Lett 17:113

    CAS  Google Scholar 

  85. Wang Z, Chang Y, Schwan AL, Notter RH (2007) Am J Resp Cell Mol Biol 37:387

    CAS  Google Scholar 

  86. Cherenok S, Vovk A, Muravyova I, Shivanyuk A, Kukhar V, Lipokowksi J, Kalchenko V (2006) Org Lett 8:549

    CAS  Google Scholar 

  87. Drag M, Grembecka J, Pawelczak M, Kafarski P (2005) Eur J Med Chem 40:764

    CAS  Google Scholar 

  88. Mucha A, Kunert A, Grembecka J, Pawelczak M, Kafarski P (2006) Eur J Med Chem 41:768

    CAS  Google Scholar 

  89. Drag M, Grzywa R, Oleksyszyn J (2007) Bioorg Med Chem Lett 17:1516

    CAS  Google Scholar 

  90. Skinner-Adams TS, Lowther J, Teuscher F, Stack CM, Grembecka J, Mucha A, Kafarski P, Treholme TR, Dalton JP, Gardiner DL (2007) J Med Chem 50:602

    Google Scholar 

  91. Teuscher F, Lowther J, Skinner-Adams TS, Spielmann T, Dixon MWA, Stack CM, Donelly S, Mucha A, Kafarski P, Vassiliou S, Gardiner DL, Dalton JP, Trenholme KR (2007) J Biol Chem 282:30817

    CAS  Google Scholar 

  92. Vassiliou S, Xeilari M, Yiotakis A, Grembecka J, Pawelczak M, Kafarski P, Mucha A (2007) Bioorg Med Chem Lett 15:3187

    CAS  Google Scholar 

  93. Holz RC (2002) Coord Chem Rev 232:5

    CAS  Google Scholar 

  94. Berlicki L, Grembecka J, Dyguda-Kazimierowicz E, Kafarski P, Sokalski WA (2007) In: Sokalski WA Molecular materials with specific interactions – modeling and design. Challenges and advances in computational chemistry and physics, vol 4. Springer, Dordrecht, pp 365–398

    Google Scholar 

  95. Mucha A, Grembecka J, Cierpicki T, Kafarski P (2003) Eur J Org Chem 4797

    Google Scholar 

  96. Stack CM, Lowther J, Cunningham E, Donelly S, Gardiner DL, Treholme KR, Skinner-Adams TS, Teuscher F, Grembecka J, Mucha A, Kafarski P, Lua L, Bell A, Dalton JP (2007) J Biol Chem 282:2069

    CAS  Google Scholar 

  97. Reiter LA, Mitchell PG, Martinelli GJ, Lopresti-Morrow LL, Yocum SA, Eskra JD (2003) Bioorg Med Chem Lett 13:2331

    CAS  Google Scholar 

  98. Dive V, Georgiadis D, Matziari M, Makaritis A, Beau F, Cuniasse P, Yiotakis A (2004) Cell Mol Life Sci 61:2010

    CAS  Google Scholar 

  99. Matziari M, Beau F, Cuniasse P, Dive V, Yiotakis A (2004) J Med Chem 47:325

    CAS  Google Scholar 

  100. Agamemnone M, Campestre C, Preziuso S, Consalvi V, Crucianelli M, Mazza F, Politi V, Ragno R, Tortorella P, Gallina C (2005) Eur J Med Chem 40:271

    Google Scholar 

  101. Bianchi G, Aschi M, Cavicchio G, Crucianelli M, Prezusio S, Gallina C, Nastari A, Gavuzzo E, Mazza F (2005) Bioorg Med Chem 13:4740

    Google Scholar 

  102. Lauer-Fields J, Brew K, Whitehead JK, Li S, Hammer RP, Fields GB (2007) J Am Chem Soc 129:10408

    CAS  Google Scholar 

  103. Matziari M, Dive V, Yiotakis A (2007) Med Res Rev 27:528

    CAS  Google Scholar 

  104. Verma RP, Hansch C (2007) Bioorg Med Chem 15:2223

    CAS  Google Scholar 

  105. Gall A-L, Ruff M, Kannan R, Cuniasse P, Yiotakis A, Dive V, Rio M-C, Basset P, Moras D (2001) J Mol Biol 307:577

    CAS  Google Scholar 

  106. Makaritis A, Georgiadis D, Dive V, Yiotakis A (2003) Chem Eur J 9:2079

    CAS  Google Scholar 

  107. Manzenrieder F, Frank AO, Kessler H (2008) Angew Chem Int Ed 47:2608

    CAS  Google Scholar 

  108. Burchardt JU, Schiødt CB, Krog-Jensen C, Delaisse J-M, Foged NT, Meldal M (2000) J Comb Chem 2:624

    Google Scholar 

  109. Devel L, Rogakos V, David A, Makartis A, Beau F, Cuniasse P, Yiotakis A, Dive V (2006) J Biol Chem 281:11152

    CAS  Google Scholar 

  110. Aschi M, Besker N, Re N, Pochetti G, Coletti C, Mazza F (2007) J Med Chem 30:211

    Google Scholar 

  111. Mallari JP, Choy CJ, Hu Y, Martinez AR, Hosaka M, Toriyabe Y, Maung J, Blecha JE, Pavkovic SF, Berkman CE (2004) Bioorg Med Chem 12:6011

    CAS  Google Scholar 

  112. Adler M, Buckman B, Bryant J, Chang Z, Chu K, Emayan K, Hrvatin P, Islam I, Morser J, Sukovich D, West C, Yuan S, Whitlow M (2008) Acta Crystallogr D64:149

    CAS  Google Scholar 

  113. Grzywa R, Oleksyszyn J (2008) Bioorg Med Chem Lett 18:3734

    CAS  Google Scholar 

  114. Payne DJ, Du W, Bateson JH (2000) Exp Opin Invest Drugs 9:247

    CAS  Google Scholar 

  115. Gurulingappa H, Buckhalts P, Kinzler KW, Vogelstein B, Khan SR (2004) Bioorg Med Chem Lett 14:3531

    CAS  Google Scholar 

  116. Smith HK, Beckett RP, Clements JM, Doel S, East SP, Launchbury SB, Pratt LM, Spavold ZM, Thomas W, Todd RS, Whittaker M (2002) Bioorg Med Chem Lett 12:3595

    CAS  Google Scholar 

  117. Kruger RG, Barkallah S, Frankel BA, McCafferty DG (2004) Bioorg Med Chem 12:3723

    CAS  Google Scholar 

  118. Corradi HR, Chitapi I, Sewell BT, Georgiadis D, Dive V, Sturrock ED, Acharya KR (2007) Biochemistry 46:5473

    CAS  Google Scholar 

  119. Mores A, Matziari M, Beau F, Cuniasse P, Yiotakis A, Dive V (2008) J Med Chem 51:2216

    CAS  Google Scholar 

  120. Bartley DM, Coward JK (2005) J Org Chem 70:6757

    CAS  Google Scholar 

  121. Feng Y, Coward JK (2006) J Med Chem 49:770–788

    CAS  Google Scholar 

  122. Yang Y, Coward JK (2007) J Org Chem 72:5748

    CAS  Google Scholar 

  123. Vidossich P, Carloni P (2006) J Phys Chem B 110:1437

    CAS  Google Scholar 

  124. Manzenrieder F, Frank AO, Huber T, Dorner-Ciossek C, Kessler H (2007) Bioorg Med Chem 15:4136

    CAS  Google Scholar 

  125. Štrancar K, Blanot D, Gobec S (2006) Bioorg Med Chem Lett 16:343

    Google Scholar 

  126. Štrancar K, Boniface A, Blanot D, Gobec S (2007) Arch Pharm Chem Life Sci 340:127

    Google Scholar 

  127. Cressina E, Lloyd AJ, De Pascale G, Roper DI, Dowson CG Bugg TDH (2007) Bioorg Med Chem Lett 17:4654

    CAS  Google Scholar 

  128. Demange L, Dugave C (2001) Tetrahedron Lett 42:6295

    CAS  Google Scholar 

  129. Gobec S, Plantan I, Mravljak J, Wilson RA, Besra GS, Kikelj D (2004) Bioorg Med Chem Lett 14:3559

    CAS  Google Scholar 

  130. Gobec S, Plantan I, Mravljak J, Švajger U, Wilson RA, Besra GS, Soares SL, Appelberg R, Kikelj D (2007) Eur J Med Chem 42:54

    CAS  Google Scholar 

  131. Han L, Hiratake J, Kamiyama A, Sakata K (2007) Biochemistry 46:1432

    CAS  Google Scholar 

  132. Mucha A, Pawelczak M, Hurek J, Kafarski P (2004) Bioorg Med Chem Lett 14:3113

    CAS  Google Scholar 

  133. Asojo O, Friedman J, Adir N, Belakhov V, Shoham Y, Baasov T (2001) Biochemistry 40:6326

    CAS  Google Scholar 

  134. Pan W, Ansiaux C, Vincent SP (2007) Tetrahedron Lett 48:4353

    CAS  Google Scholar 

  135. Suk D-H, Rejman D, Dykstra CC, Pohl R, Pankiewicz KW, Patterson SE (2007) Bioorg Med Chem Lett 17:2811

    CAS  Google Scholar 

  136. Zhou D, Staake M, Patterson S (2008) Org Lett 10:2179

    CAS  Google Scholar 

  137. Oleksyszyn J, Powers JC (1994) Amino acid and peptide phosphonate as specific inhibitors of serine peptidases. In: Barret AJ Methods in enzymology, vol 244. Academic, San Diego, pp 423–441

    Google Scholar 

  138. Skordalakes E, Dodson GG, St Clair Green D, Goodwin GA, Scully MF, Hudson HR, Kakkar VV, Deadman JJ (2001) J Mol Biol 311:549

    CAS  Google Scholar 

  139. Sienczyk M, Oleksyszyn J (2004) Tetrehedron Lett 45:7251

    CAS  Google Scholar 

  140. Joossens J, Van der Veken P, Surpateanu G, Lambeir A-M, El-Sayed I, Ali OM, Augustyns K, Haemers A (2006) J Med Chem 49:5785

    CAS  Google Scholar 

  141. Joossens J, Ali OM, El-Sayed I, Surpateanu G, Van der Veken P, Lambeir A-M, Setyono-Han B, Foeskens JA, Schneider A, Schmalix W, Haemers A, Augustyns K (2007) J Med Chem 50:6638

    CAS  Google Scholar 

  142. Gilmore BF, Lynas JF, Scott CJ, McGoohan C, Martin L, Walker B (2006) Biochem Biophys Res Commun 346:436

    CAS  Google Scholar 

  143. Augustyns K, Van der Veken P, Haemers A (2005) Curr Med Chem 12:971

    CAS  Google Scholar 

  144. Gilmore BF, Carson L, McShane LL, Quinn D, Coulter WA, Walker B (2006) Biochem Biophys Res Commun 347:373

    CAS  Google Scholar 

  145. Van der Veken P, Soroka A, Brandt I, Chen Y-S, Maes M-B, Lambeir A-M, Chen X, Haemers A, Scharpé S, Augustyns K, De Meester I (2007) J Med Chem 50:5568

    CAS  Google Scholar 

  146. Grzywa R, Dyguda-Kazimierowicz E, Sienczyk M, Feliks M, Sokalski WA, Oleksyszyn J (2007) J Mol Model 13:677

    CAS  Google Scholar 

  147. Zhou Y-X, Karle S, Tagiuchi H, Planque S, Nishiyama Y, Paul S (2002) J Immunol Meth 269:257–268

    CAS  Google Scholar 

  148. Taguchi H, Keck Z, Foung SKH, Paul S, Nishiyama Y (2004) Bioorg Med Chem Lett 14:4529

    CAS  Google Scholar 

  149. Marnett AB, Nomura AM, Shimba N, Ortiz de Montellano PR, Craik CS (2004) Proc Natl Acad Sci USA 101:6870

    CAS  Google Scholar 

  150. Planque S, Bangale Y, Song X-T, Karle S, Taguchi H, Poindexter B, Bick R, Edmundson A, Nishiyama Y, Paul S (2004) J Biol Chem 279:14024

    CAS  Google Scholar 

  151. Nishiyama Y, Mitsuda Y, Taguchi H, Planque S, Hara M, Karle S, Hanson CV, Uda T, Paul S (2005) J Mol Recogn 18:295

    CAS  Google Scholar 

  152. Nukaga M, Kumar S, Nukaga K, Pratt RF, Knox JR (2004) J Biol Chem 279:9344

    CAS  Google Scholar 

  153. Adediran SA, Nukaga M, Baurin S, Pratt RF (2005) Antimicrob Agents Chemother 49:4410

    CAS  Google Scholar 

  154. Han L, Hiratake J, Kamiyama A, Sakata K (2007) Biochemistry 46:1432

    CAS  Google Scholar 

  155. Fleisch H, Russel RGG, Staruman F (1966) Nature 212:901

    CAS  Google Scholar 

  156. Green JR (2004) Oncologist 9:4

    Google Scholar 

  157. Licata AA (2005) Ann Pharmacother 39:668

    CAS  Google Scholar 

  158. Russell RGG (2006) Ann NY Acad Sci 1068:367

    CAS  Google Scholar 

  159. Ogawa K, Mukai T, Ararno Y, Ono M, Hanaoka H, Ishino S, Hashimoto K, Nishimura H, Saji H (2005) Bioconjugate Chem 16:751

    CAS  Google Scholar 

  160. Mukherjee S, Song Y, Oldfield E (2008) J Am Chem Soc 130:1264

    CAS  Google Scholar 

  161. Shipman CM, Croucher PI, Russell RGG, Rogers MJ (1998) Cancer Res 58:5294

    CAS  Google Scholar 

  162. Ebetino FH, Roze CN, McKenna CE, Barnett CL, Dunfors JE, Russell RGG, Mielig GE, Rogers MJ (2005) J Organometal Chem 690:2679

    CAS  Google Scholar 

  163. Sanders JM, Song Y, Chan JMW, Zhang Y, Jennings S, Kosztowski T, Odeh S, Flessner R, Schwerdtfeger C, Kotsikorou E, Meints GA, Ortiz Gomaes A, Gonzales-Pacanowska D, Raker AM, Wang H, van Beek ER, Papapoulos SE, Morita CT, Oldfield E (2005) J Med Chem 48:2957

    CAS  Google Scholar 

  164. Dunford JE, Rogers MJ, Ebetino FH, Pipps RJ, Coxon FP (2006) J Bone Miner Res 21:684

    Google Scholar 

  165. Kavanagh KL, Guo K, Dunford JE, Wu X, Knapp S, Ebetino FH, Rogers MJ, Russell RGG, Oppermann U (2006) Proc Natl Acad Sci USA 103:7829

    CAS  Google Scholar 

  166. Leon A, Liu L, Yang Y, Hidock MP, Hall P, Yin F, Studer D, Puan K-J, Morita CT, Oldfield E (2006) J Med Chem 49:7331

    CAS  Google Scholar 

  167. Yin F, Cao R, Goddard A, Zhang Y, Oldfield E (2006) J Am Chem Soc 128:3524

    CAS  Google Scholar 

  168. Guo R-T, Cao R, Liang P-H, Ko T-P, Chang T-H, Hudock MP, Jeng W-J, Chen CK-M, Zhang Y, Song Y, Kuo C-J, Yin F, Oldfield E, Wang A H-J (2007) Proc Natl Acad Sci USA 104:10022

    CAS  Google Scholar 

  169. Wiemer AJ, Tong H, Swanson KM, Hohl RJ (2007) Biochem Biophys Res Commun 353:921

    CAS  Google Scholar 

  170. Dunford JE, Kwaasi AA, Rogers MJ, Barnett BL, Ebetino FH, Russell RGG, Opperman U, Kavanagh KL (2008) J Med Chem 51:2187

    CAS  Google Scholar 

  171. Hosfield DJ, Zhang Y, Dougan DR, Broun A, Tari LW, Swanson RV, Finn J (2004) J Biol Chem 279:8526

    CAS  Google Scholar 

  172. Mao J, Gao Y-G, Odeh S, Robinson H, Montavetti A, Docampo R, Oldfield E (2004) Acta Crystallogr D60:1863

    CAS  Google Scholar 

  173. Mao J, Mukherjee, Zhang Y, Cao R, Sanders JM, Song Y, Zhang Y, Meints GA, Mukkamala D, Hudock MP, Oldfield E (2006) J Am Chem Soc 128:14485

    CAS  Google Scholar 

  174. Rondeau JM, Bitsch F, Bourgier E, Geiser M, Hemming R, Kroemer M, Lehman S, Ramage P, Riffel S, Strauss A, Green JR, Jahnke W (2006) ChemMedChem 1:267

    CAS  Google Scholar 

  175. Martin MB, Arnold W, Heath III HT, Urbina JA, Oldfield E (1999) Biochem Biophys Res Commun 263:754

    CAS  Google Scholar 

  176. Berlicki L, Kafarski P (2002) Pestic Biochem Physiol 73:94

    CAS  Google Scholar 

  177. Dieterle F, Scglotterbeck G, Binder M, Ross A, Suter L, Senn H (2007) Chem Res Toxicol 20:1291

    CAS  Google Scholar 

  178. Gertz BJ, Holland SD, Kline WF, Matuszewski BK, Freeman A, Quan H, Lasseter KC, Mucklow JC, Porras AG (1995) Clin Pharmacol Therapeut 58:288

    CAS  Google Scholar 

  179. Hoffman A, Stepensky D, Ezra A, Van Gelder JM, Golomb G (2001) Int J Pharm 220:1

    CAS  Google Scholar 

  180. Vachal P, Hale JJ, Lu Z, Streckfuss EC, Mills SG, MacCoss M, Yin DH, Algayer K, Manser K, Kesisoglou F, Ghosh S, Alani LL (2006) J Med Chem 49:3060

    CAS  Google Scholar 

  181. Balas F, Manzano M, Horcjada P, Vallet-Regi M (2006) J Am Chem Soc 128:8116

    CAS  Google Scholar 

  182. Leite AF, Figueiredo PT, Melo NS, Acevedo AC, Paraiso Cavalcanti MG, Paula LM, Paula AP, Silva Guerra EN (2006) Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:14

    Google Scholar 

  183. Dannemann C, Grätz KW, Riener MO, Zwahlen RA (2007) Bone 40:828

    CAS  Google Scholar 

  184. Hess LM, Jeter JM, Benham-Hutchins M, Albers DS (2008) Am J Med 121:475

    CAS  Google Scholar 

  185. Subramaniam RM, Miller GM (2008) Eur J Radiol 66:e9

    Google Scholar 

  186. Uludag H (2002) Curr Pharm Des 8:99

    Google Scholar 

  187. Ogawa K, Mukai T, Ararno Y, Ono M, Hanaoka H, Ishino S, Hashimoto K, Nishimura H, Saji H (2005) Bioconj Chem 16:751

    CAS  Google Scholar 

  188. Ehrick RS, Capaccio M, Puelo DA, Bachas LG (2008) Bioconj Chem 19:315

    CAS  Google Scholar 

  189. Erez R, Ebner S, Attali B, Shabat D (2008) Bioorg Med Chem Lett 18:816

    CAS  Google Scholar 

  190. Urbina JA, Moreno B, Vierkotter S, Oldfield E, Payares G, Sanoja C, Bailey BN, Yan W, Scott DA, Moreno SNJ, Docampo R (1999) J Biol Chem 274:33609

    CAS  Google Scholar 

  191. Martin MB, Grimley JS, Lewis JC, Heath III HT, Bailey BN, Kendrick H, Yardley V, Caldera A, Lira R, Urbina JA, Moreno SNJ, Docampo R, Croft SL, Oldfield E (2001) J Med Chem 44:909

    CAS  Google Scholar 

  192. Martin MB, Sanders JM, Kendrick H, de Luca-Fradley K, Lewis JC, Grimley JS, van Brussel EM, Olsen JR, Meints GA, Burzynska A, Kafarski P, Croft SL, Oldfield E (2002) J Med Chem 45:2904

    CAS  Google Scholar 

  193. Szajnman SH, Bailey BN, Docampo R, Rodriguez JB (2001) Bioorg Med Chem Lett 11:789

    CAS  Google Scholar 

  194. Bouzahzah B, Jelicks LA, Morris SA, Weiss LM, Tarnowitz HB (2005) Parazitol Res 96:184

    Google Scholar 

  195. Rodriguez N, Bailey BN, Martin MB, Oldfield E, Urbina JA, Docampo R (2002) J Infect Dis 186:138

    CAS  Google Scholar 

  196. Yardley V, Khan AA, Martin MB, Slifer TR, Araujo FG, Moreno SN, Docampo R, Croft SL, Oldfield E (2002) Animicrob Agent Chemother 46:929

    CAS  Google Scholar 

  197. Garzoni LR, Waghabi MC, Baptista MM, de Castro SL, Meirelles MNL, Britto CC, Docampo R, Oldfield E, Urbina JA (2004) Int J Antimicrob Agents 23:286

    CAS  Google Scholar 

  198. Montalvetti A, Bailey BN, Martin MB, Severin GW, Oldfield E, Docampo R (2001) J Biol Chem 276:33930

    CAS  Google Scholar 

  199. Sanders JM, Gomes AO, Mao J, Meints GA, Van Brussel EM, Burzynska A, Kafarski P, Gonzales-Pacanowska D, Oldfield E (2003) J Med Chem 46:5171

    CAS  Google Scholar 

  200. Szajnman SH, Montalvetti A, Wang Y, Docampo R, Rodriguez JB (2003) Bioorg Med Chem Lett 13:3231

    CAS  Google Scholar 

  201. Szajnman SH, Ravaschino EL, Docampo R, Rodriguez JB (2005) Bioorg Med Chem Lett 15:4685

    CAS  Google Scholar 

  202. Hudock MP, Sanz-Rodriguez CE, Song Y, Chan JMW, Zhang Y, Odeh S, Kosztowski T, Leonrossell A, Cóncepcion JL, Yardely V, Croft SL, Urbina JA, Oldfield E (2006) J Med Chem 49:215

    CAS  Google Scholar 

  203. Kotsikorou E, Song Y, Chan JMW, Faelens S, Tovian Z, Broderick E, Bakalara N, Docampo R, Oldfield E (2005) J Med Chem 48:6128

    CAS  Google Scholar 

  204. Fernández D, Wenck MA, Craig III SP, Delfino JM (2004) Bioorg Med Chem Lett 14:4501

    Google Scholar 

  205. Wang L, Kamath A, Das H, Li L, Bukowski J (2001) J Clin Invest 108:1349

    CAS  Google Scholar 

  206. Verdijk R, Franke H, Vermes I (2003) Cancer Lett 246:308

    Google Scholar 

  207. Milner RJ, Farese J, Henry CJ, Selring K, Fan TM, de Lorimier L-P (2004) J Vet Intern Med 18:594

    Google Scholar 

  208. Fromigue O, Lagneaux L, Body JJ (2000) J Bone Miner Res 15:2211

    CAS  Google Scholar 

  209. Chuah C, Barnes DJ, Kwok M, Corbin A, Deininger MWN, Druker BJ, Melo JV (2005) Leukemia 19:1896

    CAS  Google Scholar 

  210. Segawa H, Kimura S, Kuroda J, Sato K, Nogawa M, Yuasa T, Yakota A, Hodohara K, Fujiyama Y, Maekawa T (2005) Leukemia Res 29:451

    CAS  Google Scholar 

  211. Roelofs AJ, Hulley PA, Meijer A, Ebetino FH, Russell RGG, Shipman CM (2006) Int J Cancer 119:1254

    CAS  Google Scholar 

  212. Horie N, Murata H, Kimura S, Takeshita H, Sakabe T, Matsui T, Kubo T, Fushiki S (2007) Brit J Cancer 96:255

    CAS  Google Scholar 

  213. Silva KL, Vasconcellos DV, Delfraro de Paula Castro E, da Cunha Vasconcelos F, Bigni R, Maia RC (2008) Cancer Chemo Pharmacol 62:165

    CAS  Google Scholar 

  214. Kunzmann V, Bauer E, Wilhelm N (1999) N Engl J Med 340:737

    CAS  Google Scholar 

  215. Wilhelm M, Kunzmann V, Eckstein S, Reimer P, Weissinger F, Ruedinger T, Tony H-P (2003) Blood 102:200

    CAS  Google Scholar 

  216. Sanders JM Ghosh S, Chan JMW, Meints GA, Wang H, Raker AM, Song Y, Colantino A, Burzynska A, Kafarski P, Morita CT, Oldfield E (2004) J Med Chem 47:375

    Google Scholar 

  217. Bukowski JF, Dascher CC, Das H (2005) Biochem Biophys Res Commun 328:746

    CAS  Google Scholar 

  218. Suzuki F, Fujikawa Y, Yamamoto S, Mizutani H, Ohya T, Ikai T, Oguchi T (1979) Ger Offen 2,831,578

    Google Scholar 

  219. Lejczak B, Boduszek B, Kafarski P, Forlani G, Wojtasek H, Wieczorek P (1996) J Plant Growth Regul 15:109

    CAS  Google Scholar 

  220. Forlani G, Kafarski P, Lejczak B, Wieczorek P (1997) J Plant Growth Regul 16:147

    CAS  Google Scholar 

  221. Kafarski P, Lejczak B, Forlani G, Gancarz R, Torreilles G, Grembecka J, Ryczek A, Wieczorek P (1997) J Plant Growth Regul 16:153

    CAS  Google Scholar 

  222. Oberhauser V, Gaudin J, Fonne-Pfister R, Schär H-P (1998) Pestic Biochem Physiol 60:111

    CAS  Google Scholar 

  223. Chuiko L, Lozinsky MO, Jasicka-Misiak I, Kafarski (1999) J Plant Growth Regul 18:171

    CAS  Google Scholar 

  224. Cromartie TH, Fisher KJ, Grossman JN (1999) Pestic Biochem Physiol 63:114

    CAS  Google Scholar 

  225. Kafarski P, Lejczak B, Forlani G (2000) Heteroatom Chem 11:449

    CAS  Google Scholar 

  226. Forlani G, Lejczak B, Kafarski P (2000) Aust J Plant Physiol 27:639

    Google Scholar 

  227. Obojska A, Berlicki L, Kafarski P, Lejczak B, Chicca M, Forlani G (2004) J Agric Food Chem 52:333

    Google Scholar 

  228. Forlani G, Lejczak B, Kafarski P (1999) J Plant Growth Regul 18:73

    CAS  Google Scholar 

  229. Gordon-Weeks R, Parmar S, Davies TGE, Leigh RA (1999) Biochem J 337:373

    CAS  Google Scholar 

  230. Szabo CM, Oldfield E (2001) Biochem Biophys Res Commun 287:468

    CAS  Google Scholar 

  231. Forlani G, Gilberti S, Berlicki L, Petrollino D, Kafarski P (2007) J Agric Food Chem 55:4340

    CAS  Google Scholar 

  232. Forlani G, Occhipinti A, Berlicjki L, Dziedziola G, Wieczorek A (2008) J Agric Food Chem 56:3193

    CAS  Google Scholar 

  233. Matczak-Jon E, Adrabinska-Videnowa V (2005) Coord Chem Rev 249:2458

    CAS  Google Scholar 

  234. Caravan P, Ellison JJ, McMurry TJ, Lauffer RB (1999) Chem Rev 99:2293

    CAS  Google Scholar 

  235. Volkert WA, Hoffman TJ (1999) Chem Rev 99:2269

    CAS  Google Scholar 

  236. Mondry A, Janicki R (2006) Dalton Trans, p 4702

    Google Scholar 

  237. Panwar P, Kumar N, Singh S, Rawat H, Mishra AK (2007) Bioorg Med Chem 15:1138

    CAS  Google Scholar 

  238. Vitha T, Kubicek V, Hermann P, Vander elst L, Muller RN, Kolar ZI, Wolterbeek HT, Breeman WAP, Lukes I, Peters JA (2008) J Med Chem 51:677

    CAS  Google Scholar 

  239. Djokic DD, Jankovic DL, Nikolic NS (2008) Bioorg Med Chem 16:4457

    CAS  Google Scholar 

  240. Goel A, Dispenzieri A, Witzig TE, Russell SJ (2006) Drug Discov Today Dis Mech 3:515

    Google Scholar 

  241. Arano Y, Mukai T, Uezono T, Wakisaka K, Motonari H, Akizawa H, Taoka Y, Yokoyama AQ (1994) J Nucl Med 35:890

    CAS  Google Scholar 

  242. Menda J, Bushnell DL, Williams RD, Miller SNR, Thomas MO (2000) Clin Nucl Med 25:698

    CAS  Google Scholar 

  243. Sapienza MT, Ono CR, Cury Guimarães MI, Watanabe T, Costa PA, Buchpiguel CA (2004) Rev Hop Clin FAc Med S Paulo 59:321

    Google Scholar 

  244. Tripathi M, Singhal T, Chandrasekhar N, Kumar P, Bal C, Jhulka PK, Bandopadhyaya G, Malhorta A (2006) Indian J Cancer 43:86

    CAS  Google Scholar 

  245. Adzamli IK, Gries H, Johnson D, Blau M (1989) J Med Chem 32:139

    CAS  Google Scholar 

  246. Alves FC, Donato P, Sherry AD, Zaheer AD, Zhand S, Lubag AJM, Merritt ME, Lenkinski RE, Frangioni JV, Neves M, Prata MIM, Santos AC, de Lima JJP, Geraldes CFGC (2003) Invest Radiol 38:750

    CAS  Google Scholar 

  247. Kubicek V, Rudowsky J, Kotek J, Herman P, Vander Elst L, Muller RN, Kolar ZI, wolterbeek HT, Peters JA, Lukes IA (2005) J Am Chem Soc 127:16477

    CAS  Google Scholar 

  248. Klenner T, Valenzuela P, Keppler BK, Scherf HR (1990) J Cancer Res Clin Oncol 116:453

    CAS  Google Scholar 

  249. Margiotta N, Ostuni R, Teoli D, Morpu rgo M, Realdon R, Palazzo B, Natali G (2007) Dalton Trans, p 3131

    Google Scholar 

  250. Wang L, Yang Z, Gao J, Xu K, Gu K, Zhang B, Zhang X, Xu B (2006) J Am Chem Soc 128:13358

    CAS  Google Scholar 

  251. Chaleix V, Lecouvey M (2007) Tetrahedron Lett 48:703

    CAS  Google Scholar 

  252. Poupot M, Griffe L, Marchand P, Maraval A, Rolland O, Martinet L, Turrin C-O, Caminade V, Fournie J-J, Majoral J-P, Poupot R (2006) FASEB J 20:2339

    CAS  Google Scholar 

  253. Griffe L, Poupot P, Marchand P, Marval O, Turrin C-O, Rolland O, Métivier P, Bacquet G, Fournié J-J, Caminade A-M, Poupot R, Majoral J-P (2007) Angew Chem Int Ed 46:2523

    CAS  Google Scholar 

  254. Rolland O, Griffe L, Poupot M, Maraval A, Ouali A, Coppel Y, Fournié J-J, Bacquet G, Turrin C-O, Caminadse A-M, MAjoral J-P, Poupot R (2008) Chem Eur J 14:4836

    CAS  Google Scholar 

  255. Kamiya T, Hemmi H, Takeno H, Hashimoto M (1980) Tetrahedron Lett 21:95

    CAS  Google Scholar 

  256. Hashimoto M, Hemmi K, Takeno H, Kamiya T (1980) Tetrahedron Lett 21:99

    CAS  Google Scholar 

  257. Kuzuyama T, Shimizu T, Takahashi S, Seto H (1998) Tetrahedron Lett 39:7913

    CAS  Google Scholar 

  258. Jomaa H, Wiesner J, Sanderbrand S, Altincicek B, Weidemeyer C, Hintz M, Turbachova I, Eberl M, Zeidler J, Lichtenthaler HK, Soldati D, Beck E (1999) Science 285:1573

    CAS  Google Scholar 

  259. Kuzuyama T, Takahashi S, Tagaki M, Seto H (2000) J Biol Chem 275:19928

    CAS  Google Scholar 

  260. Eisenreich W, Rohdich F, Bacher A (2001) Trends Plant Sci 6:78

    CAS  Google Scholar 

  261. Wiesner J, Seeber F (2005) Expert Opin Ther Targest 9:23

    CAS  Google Scholar 

  262. Missinou MA, Borrmann G, Schindler A, Issifou S, Adegnika AA, Matsiegui PB, Binder R, Lell B, Wiesner J, Baranek T, Jomaa H, Kremsner PG (2002) Lancet 360:1941

    CAS  Google Scholar 

  263. Lell B, Ruangweerayut R, Wiesner J, Missinou MA, Schindler A, Baranek T, Hintz M, Hutchinson D, Jomaa H, Kremsner PG (2003) Antimicrob Agents Chemother 47:735

    CAS  Google Scholar 

  264. Reichenberger A, Wiesner J, Weidemeyer C, Dreiseidler E, Sanderbrand S, Altincicek B, Beck E, Schlitzer M, Jomaa H (2001) Bioorg Med Chem Lett 11:833

    Google Scholar 

  265. Ortmann R, Wiesner J, Reichenberg A, Henschker D, Beck E, Jomaa H, Schilzer M (2005) Arch Pharm Life Sci 338:305

    CAS  Google Scholar 

  266. Kurz T, Schülter K, Kaula U, Bergmann B, Walter RD, Geffken D (2006) Bioorg Med Chem 14:5121

    CAS  Google Scholar 

  267. Schülter K, Walter RG Bergmann B, Kurz T (2006) Eur J Med Chem 41:1385

    Google Scholar 

  268. Haemers T, Wiesner J, Van Poecke S, Goeman J, Henschker D, Beck E, Jomaa H, Van Calenbergh S (2006) Bioorg Med Chem Lett 16:1888

    CAS  Google Scholar 

  269. Devreux V, Wiesner J, Jomaa H, Rozenski J, Van der Eycken J, Van Calenbergh S (2008) J Org Chem 72:3783

    Google Scholar 

  270. Courtois M, Mincheva Z, Andreu F, Rideau M, Viaud-Massuard MC (2004) J Enzyme Inhib Med Chem 19:559

    CAS  Google Scholar 

  271. Kuntz L, Trisch D, Grosdemange-Billiard C, Hemmerlin A, Willem A, Bach TJ, Rohmer M (2005) Biochem J 386:127

    CAS  Google Scholar 

  272. Haemers T, Wiesner J, Giesmann D, Verbrugghen T, Hillaert U, Ortmann R, Jomaa H, Link A, Schilzer M, Van Calenbergh S (2008) Bioorg Med Chem 16:3361

    CAS  Google Scholar 

  273. Mincheva Z, Courtois M, Andreu F, Rideau M, Viaud-Massuard M-C (2005) Phytochemistry 66:1797

    CAS  Google Scholar 

  274. Seto H, Kuzuyama T (1999) Nat Prod Rep 16:589

    CAS  Google Scholar 

  275. Yamato M, Koguchi T, Okachi R, Yamada K, Nakayama K, Kase H, Karasawa A, Shuto K (1986) J Antibiot 39:44

    CAS  Google Scholar 

  276. Ntai I, Bachmann B (2008) Bioorg Med Chem Lett 18:3068

    CAS  Google Scholar 

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  1. Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370, Wroclaw, Poland

    Barbara Lejczak & Pawel Kafarski

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  1. Barbara Lejczak
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  2. Pawel Kafarski
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  1. Dept. Chemistry, University of Rajasthan, Jaipur, 302004, India

    Raj K. Bansal

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Lejczak, B., Kafarski, P. (2009). Biological Activity of Aminophosphonic Acids and Their Short Peptides. In: Bansal, R. (eds) Phosphorous Heterocycles I. Topics in Heterocyclic Chemistry, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2008_14

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