Abstract
Numerous investigations have been carried out to elucidate cholinergic mechanisms in the central nervous system (CNS). Bhattacharya and Feldberg (1958), using perfusion of cerebral ventricles in cat, found that acetylcholine (ACh) was released into the effluent. Ryall (1963) reported that ACh is contained within synaptic endings and Curtis, Ryall and Wilkins (1965) observed the presence of ACh, cholinacetylase and cholinesterase in the CNS. Dhawan, Gupta, Dixit and Chandra (1965) showed the presence of muscarinic receptors in the CNS of dogs.
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Saxena, R.C., Dixit, K.S., Dhasmana, K.M., Kohli, R.P. (1976). Effect of nicotine administration into the lateral cerebral ventricles of mice provides evidence for cholinergic mechanisms in the CNS. In: Bradley, P.B., Dhawan, B.N. (eds) Drugs and Central Synaptic Transmission. Palgrave, London. https://doi.org/10.1007/978-1-349-01247-3_12
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DOI: https://doi.org/10.1007/978-1-349-01247-3_12
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