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Alveolar Epithelial Fluid Transport Under Normal and Pathological Conditions

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Acute Respiratory Distress Syndrome

Part of the book series: NATO ASI Series ((NSSA,volume 297))

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Abstract

This chapter focuses on the mechanisms of salt and water transport across alveolar and distal airway epithelium of the adult lung. The first section presents evidence for active sodium transport as a mechanism for regulating in vivo alveolar fluid clearance, including a discussion of catecholamine and non-catecholamine dependent mechanisms for stimulating fluid transport. The second section reviews new evidence for involvement of transcellular water channels in alveolar and distal airway fluid transport, and the third section describes how the normal capacity of the alveolar epithelial barrier to transport salt and water is altered by exposure to clinically relevant pathological conditions).

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Authors and Affiliations

  1. Cardiovascular Research Institute, University of California, San Francisco, USA

    Michael A. Matthay, Colleen Horan, Chun-Xue Bai & Yibing Wang

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  1. Michael A. Matthay
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  2. Colleen Horan
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  4. Yibing Wang
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Editors and Affiliations

  1. The University of Alabama at Birmingham, Birmingham, Alabama, USA

    Sadis Matalon

  2. University of Illinois at Chicago, Chicago, Illinois, USA

    Jacob Lasha Sznajder

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© 1998 Plenum Press, New York

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Matthay, M.A., Horan, C., Bai, CX., Wang, Y. (1998). Alveolar Epithelial Fluid Transport Under Normal and Pathological Conditions. In: Matalon, S., Sznajder, J.L. (eds) Acute Respiratory Distress Syndrome. NATO ASI Series, vol 297. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8634-4_10

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  • DOI: https://doi.org/10.1007/978-1-4419-8634-4_10

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