Abstract
The transforming growth factor-β (TGF-β) superfamily consists of multifunctional proteins that include TGF-βs, activins, inhibins, and bone morphogenetic proteins (BMPs), which regulate growth, differentiation, metabolism, and apoptosis of various cell types (1,2). Members of the TGF-β superfamily transduce signals via heteromeric complexes of two different serine/threonine kinase receptors, denoted type I and type II. Both type I and type II receptors are required for signal transduction (3).
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Miyazono, K. et al. (1997). Transforming Growth Factor-β Receptors and Signal Transduction. In: Aono, T., Sugino, H., Vale, W.W. (eds) Inhibin, Activin and Follistatin. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1874-6_26
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DOI: https://doi.org/10.1007/978-1-4612-1874-6_26
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