Abstract
Implicit in this statement is the fact that we may devise efficacious forms of menopausal hormone replacement therapy (HRT) and yet the desired benefits may not be achieved because other factors result in noncompliance. Although the magnitude and pervasiveness of noncompliance with menopausal HRT has generally been acknowledged, this issue has played a limited role in assessment, decision making, policy setting, and individual patient care.1 This chapter examines the range of issues that may have an impact upon the two components of compliance—commencement and maintenance. In general, these can be divided into three major categories: physicians’ concerns, patients’ concerns, and third party concerns. The current state of compliance with available menopausal HRT regimens will be reviewed and recommendations given that may lead to improvement of utilization for those in whom HRT is deemed appropriate.
Treatment based on what is efficacious may substantially differ from treatment based on what is effective.
Speroff, et al.1
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References
Speroff T, Dawson NV, Speroff L, Haber RJ. A risk-benefit analysis of elective bilateral oophorectomy: effect of changes in compliance with estrogen therapy on outcome. Am J Obstet Gynecol. 1991; 164: 165.
Ravnikar VA. Compliance with hormone therapy. Am J Obstet Gynecol. 1987; 154: 1332.
Bartlett EE. Patient counselling for osteoporosis prevention. In: Proceedings of the National Conference on Women’s Health Series, Special Topic Conference on Osteoporosis. J US Public Health Service. 1989;Suppl SeptOct:87.
Norris JA. Welcoming remarks. In: Proceedings of the National Conference on Women’s Health Series, Special Topic Conference on Osteoporosis. J US Public Health Service. 1989;Suppl Sept—Oct:7–8.
Ross RK. Progestogens and the cardiovascular system. Int Proc J. 1989; 1: 218.
Henderson BE, Ross RL, Lobo R, Pike MC, Mack TM. Reevaluating the role of progestogen therapy after the menopause. Fertil Steril. 1988; 49 (Suppl 5): 95.
Reid RL. Progestins in the menopause: good news and bad news. J SOCG (Can). 1990; 12 (9): 31.
Holtzman GB, Ravitch MM, Metheny W, et al. Physicians’ judgments about estrogen replace ment therapy for menopausal women. Obstet Gynecol. 1984; 71: 39.
Ferguson KJ, Hoegh C, Johnson S. Estrogen replacement therapy: a survey of women’s knowledge and attitudes. Arch Int Med. 1989; 149: 133.
Notelovitz M. Hormonal therapy in climac teric women and its socioeconomic impact. In: Proceedings of the National Conference on Women’s Health Series, Special Topic Confer ence on Osteoporosis. J US Public Health Service. 1989; Suppl Sept-Oct:70–75.
Armstrong B. Oestrogen therapy after the menopause- boon or bane? Med J Aust. 1988; 213. 148; 213.
Ettinger B. Optimal use of postmenopausal hormone replacement. Obstet Gynecol. 1988; 72 (Suppl): 31.
Hahn RG, Nachtigall RD, Davis TC. Compli ance difficulties with progestin-supplemented estrogen replacement therapy. J Fam Pract. 1984; 18: 411.
Hahn RG. Compliance considerations with estrogen replacement: withdrawal bleeding and other factors. Am J Obstet Gynecol. 1989; 161:1854. 15. Magos AL, Brincat M, Studd JWW, et al. Amenorrhea and endometrial atrophy with continuous oral estrogen and progestogen therapy in postmenopausal women. Obstet Gynecol. 1985; 65: 496.
Magos AL, Brincat E, Singh R, O’Dowd T, Brincat M, Studd JWW. The effects of norethi premenstrual syndrome. Br J Obstet Gynecol. 1986; 93: 1290
Kirkham C, Hahn PM, Van Vugt DA, Car- michael JA, Reid RL. A randomized double- blind, placebo-controlled, cross-over trial to assess the side effects of medroxyprogesterone acetate in hormone replacement therapy. Ob- stet Gynecol. 1991;78(1).
Steiner M, Haskett RF, Carroll BJ. Premen strual tension syndrome: the development of research diagnostic criteria and new rating scales. Acta Psychiatr Scand. 1980; 62: 177 190.
Beck AT, Ward CH, Mendelson M, Mock J, Erbaught J. An inventory measuring depres-sion. Arch Gen Psychiatr. 1961; 4: 561–571.
Bell SA. Premenstrual syndrome and the med-icalization of the menopause. In: Ginsburg BE, Carter BF eds. Premenstrual Syndrome.New York: Plenum Press; 1987: 151–174.
Ross RK, Paganini-Hill A, Mack TM, Arthur M, Henderson BE. Menopausal oestrogen therapy and protection from death from ischaemic heart disease. Lancet. 1981; 1: 858.
Stampfer MJ, Willet WC, Colditz GA, Rosner B, Speizer FE, Hennekens CH. A prospective study of postmenopausal estrogen therapy and coronary heart disease. N Engl J Med. 1985; 313: 1044.
Paganini-Hill A, Ross Rk, Gerkins VR, Hen- derson BE, Arthur M, Mack TM. Menopausal estrogen therapy and hip fractures. Ann In- tern Med. 1981; 95: 28.
Kaufman DW, Miller DR, Rosenberg L, et al. Noncontraceptive estrogen use and risk of breast cancer. JAMA. 1984; 252: 63.
Kelsey JL, Fischer DB, Holford TR, et al. Exogenous estrogens and other factors in the epidemiology of breast cancer. JNCI. 1981; 67: 327.
Hiat RA, Bawal R, Friedman GD, Hoover R. Exogenous estrogen and breast cancer after bilateral oophorectomy. Cancer. 1980; 54: 139.
Brinton LA, Hoover RN, Szklo M, Fraumeni JF. Menopausal estrogen use and risk of breast cancer. Cancer. 1981; 47: 2517.
Dennerstein L, Wood C, Burrows GD. Sexual response following hysterectomy and oophor- ectomy. Obstet Gynecol. 1977; 49: 92.
Ritterband AB, Jaffe IA, Densen PM, Magagna sterone in postmenopausal women on estro- gen replacement therapy: a model for the JF, Reed E. Gonadal function and the develop-ment of coronary heart disease. Circulation.
Rosenberg L, Slone D, Shapiro S, Kaufman D,1963;27:237. Stolley PD, Miettinen OS. Noncontraceptive estrogens and myocardial infarction in young women. JAMA. 1980; 244: 339.
Washnich R, Yano K, Vogel J. Postmeno-pausal bone loss at multiple skeletal site: relationship to estrogen use. J Chronic Dis. 1983; 36: 781.
Weiss NS, Ure CL, Ballard JH, Williams AR,use of estrogen. N Engl J Med. 1195, 1980. Daling JR. Decreased risk of fractures of the hip and lower forearm with postmenopausal
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Jamieson, M.A., Reid, R.L. (1994). Compliance with Menopausal Hormone Replacement Therapy. In: Lorrain, J., Plouffe, L., Ravnikar, V.A., Speroff, L., Watts, N.B. (eds) Comprehensive Management of Menopause. Clinical Perspectives in Obstetrics and Gynecology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4330-4_29
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DOI: https://doi.org/10.1007/978-1-4612-4330-4_29
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