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Endothelium-Dependent Responses in Large Arteries and in the Microcirculation

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Relaxing and Contracting Factors

Part of the book series: The Endothelium ((TEEN))

Abstract

Studies focusing on specific components of the blood vessel wall have yielded an important secret of how the “microenvironment” can control large and small artery diameter. As a result of the now classic discovery of endothelium-derived relaxing factor (EDRF) by Furchgott and Zawad-zki (1980), any discussion of the physiology or pathology of vascular reactivity must consider the integrity and function of the cells lining the intimal surface.

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© 1988 The Humana Press Inc.

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Angus, J.A., Cocks, T.M., Wright, C.E., Satoh, K., Campbell, G.R. (1988). Endothelium-Dependent Responses in Large Arteries and in the Microcirculation. In: Vanhoutte, P.M. (eds) Relaxing and Contracting Factors. The Endothelium. Humana Press. https://doi.org/10.1007/978-1-4612-4588-9_18

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  • DOI: https://doi.org/10.1007/978-1-4612-4588-9_18

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-8939-5

  • Online ISBN: 978-1-4612-4588-9

  • eBook Packages: Springer Book Archive

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