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Idiotypic Interactions in the Treatment of Human Diseases

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Antibodies

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Abstract

The importance of the idiotypic network in the regulation of the immune response of experimental animals has been amply established. The role of the idiotypic anti-idiotypic interactions in the regulation of the human immune response to antigen has been less extensively studied. In this review we will discuss data obtained from our laboratory 011 the role the idiotypic network plays in the regulation of human immunity in health and in disease states.

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Authors and Affiliations

  1. Division of Allergy, The Children’s Hospital, Boston, Massachusetts, USA

    Raif S. Geha

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  1. Raif S. Geha
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Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, Unversity of South Florida, Tampa, Florida, USA

    Andor Szentivanyi M.D. (Dean of the College of Medicine, Deputy Vice President for Medical Affairs, Chairman and Professor) (Dean of the College of Medicine, Deputy Vice President for Medical Affairs, Chairman and Professor)

  2. Department of Biochemistry, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    Paul H. Maurer Ph.D. (Chairman and Professor) (Chairman and Professor)

  3. Immunology, Allergic and Immunologic Diseases Program National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, USA

    Bernard W. Janicki Ph.D. (Deputy Director) (Deputy Director)

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© 1987 Plenum Press, New York

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Geha, R.S. (1987). Idiotypic Interactions in the Treatment of Human Diseases. In: Szentivanyi, A., Maurer, P.H., Janicki, B.W. (eds) Antibodies. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1873-6_12

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  • DOI: https://doi.org/10.1007/978-1-4613-1873-6_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9044-5

  • Online ISBN: 978-1-4613-1873-6

  • eBook Packages: Springer Book Archive

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