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Thermodynamic Assessment of Platelet Adhesion to Polyacrylamide Gels

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Polymers as Biomaterials

Abstract

Hydrogels elicit a low cellular adhesion in vitro when measured by platelet adhesion tests under static conditions (1,2). A thermodynamic model has been described which predicts the level of cellular adhesion and protein adsorption to a range of polymer surfaces (3,4). The aim of this model is to elucidate the possible mechanisms of cell adhesion and protein adsorption, and to use this knowledge for the development of non-thrombogenic biocompatible implant materials.

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© 1984 Plenum Press, New York

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Absolom, D.R., Foo, M.H., Zingg, W., Neumann, A.W. (1984). Thermodynamic Assessment of Platelet Adhesion to Polyacrylamide Gels. In: Shalaby, S.W., Hoffman, A.S., Ratner, B.D., Horbett, T.A. (eds) Polymers as Biomaterials. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2433-1_11

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  • DOI: https://doi.org/10.1007/978-1-4613-2433-1_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9480-1

  • Online ISBN: 978-1-4613-2433-1

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