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Chemical Mutagens and Sister-Chromatid Exchange

  • Chapter
Chemical Mutagens

Abstract

The recent introduction of the sister-chromatid exchange (SCE) test has revolutionized the cytogenetic approach to the identification of biologically hazardous chemicals. Increasingly, laboratories are turning to this technique in preference to scoring chromosome aberrations. This chapter explores some of the problems and perspectives of the SCE test and reviews some of the results obtained so far.

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Authors and Affiliations

  1. M.R.C. Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh, EH4 2XU, Scotland

    Paul E. Perry

  2. Laboratory of Radiobiology, University of California, San Francisco, California, 94143, USA

    Paul E. Perry

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  1. Paul E. Perry
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  1. National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

    Frederick J. de Serres

  2. Associated Universities, Inc., Washington, D. C., USA

    Alexander Hollaender

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© 1980 Plenum Press, New York

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Perry, P.E. (1980). Chemical Mutagens and Sister-Chromatid Exchange. In: de Serres, F.J., Hollaender, A. (eds) Chemical Mutagens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3072-1_1

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  • DOI: https://doi.org/10.1007/978-1-4613-3072-1_1

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