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Activation of the Embryonic Genome: Comparisons Between Mouse and Bovine Development

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Preimplantation Embryo Development

Part of the book series: Serono Symposia, USA Norwell, Massachusetts ((SERONOSYMP))

Abstract

Eutherian mammalian preimplantation development includes an essential transitional period during which the embryo proceeds from an initial interval of maternal control (established during oogenesis) to embryonic control resulting from the activation of transcriptional activity from the embryonic genome (1–3). As for most aspects of early mammalian development, the events surrounding the activation of the embryonic genome are most readily examined in the mouse. There is, however, evidence to suggest that the mouse may display a pattern of preimplantation development (certainly in the timing of the major events) that is unique. It is, therefore, essential to broaden the analysis of preimplantation development to include other mammalian species. A comparison of several species in Table 9.1 shows that there is considerable variation in the timing, cell number, and developmental stage at which the early embryos of these groups undergo the major morphogenetic events of preimplantation development (4, 5). As shown in Table 9.2, these variations also reflect contrasts in the timing of the molecular and biochemical events of preimplantation development.

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Authors
  1. Andrew J. Watson
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  2. Aileen Hogan
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  3. Ann Hahnel
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  4. Gilbert A. Schultz
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Editors and Affiliations

  1. Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 53706, Madison, WI, USA

    Barry D. Bavister Ph.D.

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Watson, A.J., Hogan, A., Hahnel, A., Schultz, G.A. (1993). Activation of the Embryonic Genome: Comparisons Between Mouse and Bovine Development. In: Bavister, B.D. (eds) Preimplantation Embryo Development. Serono Symposia, USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9317-7_9

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  • DOI: https://doi.org/10.1007/978-1-4613-9317-7_9

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