Abstract
In warm-blooded animals water makes up about 60 percent of the body weight and exists as a solution of organic and mineral substances. This water is in constant exchange with the environment as a result of periodic uptake from the gut and continual loss through the skin, respiratory passages, and kidney. Within the body the water is distributed in several more or less discrete compartments whose contents are called the “body fluids.” The anatomical boundaries separating these compartments and the differences in the solutes present in each are of fundamental biological significance.
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References
Adolph, E. F. Measurements of water drinking in dogs. Amer. J. Physiol. 125, 75 (1939).
Adolph, E. F. Physiology of wan in the desert. New York: Interscience (1947).
Anderson, B. The effect of injections of hypertonic NaCl-solutions into different parts of the hypothalamus of goats. Acta Physiol. Scand. 28, 188 (1953).
Anderson, B. and B. Larsson. Influence of local temperature changes in the preoptic area and rostral hypothalamus on the regulation of food and water intake. Acta Physiol. Scand. 52, 75 (1961).
Arndt, J. O. Diuresis induced by water infusion into the carotid loop and its inhibition by small hemorrhage. The competition of volume- and osmo- control. Pflugers Arch. Physiol. 282, 313 (1965).
Arndt, J. O., and O. H. Gauer. Diuresis induced by water infusion into the carotid loop of unanesthetized dogs. Pflugers Arch. Physiol. 282, 301 (1965).
Arons, W. L., R. J. Vanderlinde, and A. K. Solomon. The simultaneous measurement of exchangeable body sodium and potassium utilizing ion exchanges chromatography. J. Clin. Invest. 33, 1001 (1954).
August, J. Th., and D. H. Nelson. Adjustment to aldosterone of desoxy-corticosterone acetate induced sodium retention in patients with Addison’s disease. J. Clin. Invest. 2, 1964 (1959).
August, J. T., D. H. Nelson, and G. W. Thorn. Response of normal subjects to large amounts of aldosterone. J. Clin. Invest. 37: 1549 (1958).
Bentzel, C. J., and A. K. Solomon. Osmotic properties of mitochondria. J. Gen. Phys. 50, 1547 (1967).
Bernard, Cl. Leçons sur les phénomènes de la Vie Commune aux animaux et aux végétaux. Paris: Baillière(1878).
Bombard, A. La servie prolongée en mer. Rapport technique de l’expérience de survie prolongée en mer à bord de l’Hérétique, en 1952. Editions de Paris (1954).
Code, C. F., P. Bass, G. B. McClary, L. Newnum, and A. L. Orvis. Absorption of water, sodium, and potassium in small intestine of dogs. Am. J. Physiol. 199, 281 (1960).
Cook, J. S. Non-solvent water in human erythrocytes. J. Gen. Physiol. 50, 1311 (1967).
Cross, B. A., and J. D. Green. Activity of single neurons in the hypothalamus: Effect of osmotic and other stimuli. J. Physiol., London 148, 554 (1959).
Davies, R. E., H. L. Kornberg, and G. M. Wilson. The determination of sodium in bone. Biochem. J. 52, 15 (1952).
Deane, N. Intracellular water in man. J. Clin. Invest. 30, 1469 (1951).
Diamond, J. M. The mechanism of isotonic water absorption and secretion. Symp. Soc. Exp. Biol. 19, 329 (1965).
Edelmann, I. S., A. H. James, L. Brooks, and F. D. Moore. Body sodium and potassium. IV. The normal exchangeable sodium, its measurement and magnitude. Metabolism 3, 530 (1954).
Edelman, I. S. and J. Leibman. Anatomy of body water and electrolytes. Amer. J. Med. 27, 256 (1959).
Ellinghaus, K. Elektrolyt- und Wasserbilanz unter der Wirking von DOC A bei unterschiedlicher oraler Na-Zufuhr an Hunden. Inaug. Dissert. München (1969).
Fenn, W. O., T. R. Noonan, L. J. Mullins, and L. F. Haege. The exchange of radioactive potassium with body potassium. Am. J. Physiol. 135, 149 (1941).
Gauer, O. H., and J. P. Henry. Beitrag zur Homöostase des extraarteriellen Kreislaufs. Klin. Wschr. 34, 356 (1956).
Gauer, O. H. and J. P. Henry. Circulatory basis of fluid volume control. Physiol. Rev. 43, 423 (1963).
Gregersen, M. I. Blood volume. Ann Rev. Physiol. 13, 397 (1951).
Haberich, F. J., O. Aziz, and P. E. Nowack. Fliissigkeitsspeicherung in der Leber nach Enteraler Wasserresorption. Pflugers Arch. Physiol. 288, 306 (1966).
Haberich, F. J., O. Aziz and W. Ohm. Untersuchungen zur Spezifität des Osmorezeptors in der Leber. Pflugers Arch. Physiol. 294, 36 (1967).
Hall, F. G. The vital limit of certain animals. Biol. Bull. 42, 30 (1922).
Hevesey, G., and E. Hofer. Die Verweilzeit des Wassers im menschlichen Körper; untersucht mit Hilfe von ‘schwerem’ Wasser als Indikator. Klin’ Wschr. 13, 1524 (1934).
Heyerdahl, T. Kon-Tiki: Across the Pacific by Raft. Chicago: Rand McNally, 132–133(1950).
Jewell, P. A., and E. B. Verney. An experimental attempt to determine the site of neurohypophyseal osmoreceptors in the dog. Phil. Trans. 240, 197 (1957).
Keck, W., H. Brechtelbauer, and K. Kramer. Wasser- und Na-Ausscheidung nach isotonen Kochsalz-Infusionen bei wachen Hunden mit verschie¬denem Natriumbestand. Pflugers Arch. Physiol. 311, 119 (1969).
Kerpel-Fronius, E., and F. Leovey. Über die Störung der Osmo-Regulation bei der experimentellen Exsikkose. Arch. Kinderheilkunde 94, 9 (1931).
Keys, A., and J. Brozek. Body fat in adult man. Physiol, Rev. 33, 245 (1953).
Kruhoefer, P. Inulin as an indicator for the extracellular space. Acta Physiol. Scand. 11, 16 (1946).
Ladell, W. S. S. Effects on man of restricted water-supply. Brit. M. Bull. 5, 9–13 (1947).
Ladell, W. S. S. The effects of water and salt intake upon the performance of men working in hot and humid environments. J. Physiol. 127, 11 (1955).
Ling, N., M. M. Ochsenfeld, and G. Karreman. Is the cell membrane a universal rate-limiting barrier to the movement of water between the living cell and its surrounding medium ? J. Gen. Phys. 50, 1807 (1967).
Ljunggren, H., D. Ikkos, and R. Luft. Studies on body composition. I. Body fluid compartments and exchangeable potassium in normal males and females. Acta Endocrinol. 25, 187 (1957).
Love, A. H. G., T. G. Mitchell, and R. A. Philipps. Water and sodium absorption in the human intestine. J. Physiol. 195, 133 (1968).
Manery, J. F., I. S. Danielson, and A. B. Hastings. Connective tissue electrolytes. J. Biol. Chem. 124, 359 (1938).
Miller, H., and G. M. Wilson. The measurement of exchangeable sodium in man using the isotope 24Na. Clin. Sci. 12, 97 (1958).
Moore, F. D. Determination of total body water and solids with isotopes. Science 104, 157 (1946).
O’Meara, M. P., L. W. Birkenfeld, F. A. Gotch and I. S. Edelman. The equilibration of radiosodium (24Na), radio-potassium (42K), and deuterium oxide (D20) in hydropic human subjects. J. Clin. Invest. 36, 784 (1957).
Pappenheimer, J. R., E. M. Renkin, and L. M. Borrero. Filtration, diffusion, and molecular sieving through peripheral capillary membranes. Am. J. Physiol. 167, 13(1951).
Pauling, L. Die Natur der chemischen Bindung. Verlag Chemie, Weinheim/ Bergstr. (1962).
Peters, J. P. Water exchange. Physiol. Rev. 24, 391 (1944).
Porat, von B. Blood volume determination with Evans-blue dye method. Acta Med. Scandinav. (Suppl. 256 ) 140, 1 (1951).
Pfeffer, W. Osmotische Untersuchungen. 2. Aufl. Leipzig: Engelmann. (1921).
Reinhardt, H. W., and D. W. Behrenbeck, Untersuchungen an wachen Hunden über die Einstellung der Natriumbilanz. I. Mitt: Die Bedeutung des Extrazellulär-raumes für die Einstellung der Natrium-Tagesbilanz. Pflugers Arch. Physiol. 295, 266 (1967).
Robinson, C. V., W. L. Arons, and A. K. Solomon. An improved method for simultaneous determination of exchangeable body sodium and potassium. J. Clin. Invest. 34, 134 (1955).
Robinson, E. A., and E. F. Adolph. Pattern of normal water drinking in dogs. Am. J. Physiol. 139, 39 (1943).
Robinson, S., and A. H. Robinson. Chemical composition of sweat. Physiol. Rev. 34, 202 (1954).
Rothman, S. Physiology and biochemistry of the skin. Chicago Press: Chicago University. (1954).
Schmidt-Nielsen, B., K. Schmidt-Nielsen, T. R. Houpt, and S. A. Jarnum. Water balance of the camel. Am. J. Physiol. 185, 185 (1956).
Schwiegk, H., and G. Riecker. Pathophysiologic der Herzinsuffiziens. In Handb. inn. Med. Bd. IX, 1. Berlin-Göttingen-Heidelberg: Springer- Verlag (1960).
Smith, H. W. From fish to philosopher. The story of our internal environment. Boston, Mass.: Little, Brown & Co. (1953).
Smyth, D. H. Water movement across the mammalian gut. Symp. Soc. Exp. Biol. XIX. 307 (1965).
Steele, J. M., E. Y. Berger, M. F. Dunnung, and B. B. Brodie. Total body water in man. Am. J. Physiol. 162, 313 (1950).
Verney, E. B. Antidiuretic hormone and the factors which determine its release. Proc. Roy. Soc. London 135, 25 (1947).
Volhardt, F., and E. Schütte. Über die Verträglichkeit von Meerwasser. Dtsch. Med. Wschr. 75, 1425 (1950).
Weir, E. G., and A. B. Hastings. The distribution of bromide and chloride in tissues and body fluids. J. Biol. Chem. 129, 547 (1939).
Widdowson, E. M., R. A. McCance, and C. M. Spray. The chemical composition of the human body. Clin. Sci. 10, 113 (1951).
Wolf, A. V. Thirst. C. C. Thomas: Springfield (1958).
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Deetjen, P., Boylan, J.W., Kramer, K. (1975). Salt and Water Balance. In: Physiology of the Kidney and of Water Balance. Springer Study Edition. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9375-7_2
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DOI: https://doi.org/10.1007/978-1-4613-9375-7_2
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