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Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Australia

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The Brain-Dead Organ Donor

Abstract

Deceased organ donors in Australia are cared for primarily by intensive care specialists and nurses in close consultation with organ and tissue donor coordinators and transplant teams. There has been a substantial increase in the number of deceased multiorgan donors in Australia over the last 4 years. Most of this increase has resulted from increased utilization of DCD (donation after circulatory death) donors and older DBD (donation after brain death) donors. More than 90% of DBD donors are maintained on vasoactive medication after brain death with noradrenaline being the drug of choice in most ICUs. In contrast, the utilization of hormonal therapies either singly or in combination is highly variable across the country. Use of triiodothyronine (T3) remains controversial. In recent years, T3 has been administered to 24% of DBD donors, usually in combination with methylprednisolone, vasopressin, and insulin as a combined hormonal protocol for potential cardiothoracic organ donors. Management of the DBD donor in Australia would be facilitated by the development of a nationally uniform evidence-based donor management protocol.

On behalf of the Australian Deceased Donor Management Research Group, Members of the Australian Deceased Donor Management Research Group include Anders E.M. Aneman, Deepak Bhonagiri, Tina A. Coco, Amy E. Williams, Geoffrey J. Dobb on behalf of the Australian Deceased Donor Management Research Group, Espedito E. Faraone, Catherine Hannan, Daryl Jones, Peter S. Macdonald, Gerry O’Callaghan, Helen I. Opdam, Francesca M. Rourke, William Silvester, and Jodie Talbot.

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Correspondence to Peter S. Macdonald M.B.B.S., M.D., Ph.D. .

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Macdonald, P.S. et al. (2013). Assessment, Monitoring, and Management of Brain-Dead Potential Organ Donors in Australia. In: Novitzky, D., Cooper, D. (eds) The Brain-Dead Organ Donor. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4304-9_19

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  • DOI: https://doi.org/10.1007/978-1-4614-4304-9_19

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