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Hybrid Parameter Optimization Methods

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Encyclopedia of Computational Neuroscience
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Definition

Hybrid parameter optimization (HPO) methods are search strategies that combine the strengths of different optimization algorithms to increase the performance of the overall parameter search process.

Detailed Description

Parameter optimization tends to be very complex, especially for the situations it is used for in computational neuroscience. Due to the many nonlinearities in neuronal systems and the large number of free parameters, the fitness landscapes tend to be highly dimensional and non-convex (Prinz et al. 2003; Achard and De Schutter 2006; Druckmann et al. 2007). Every optimization algorithm is optimal for certain shapes and sizes of the solution space (Achard et al. 2010). Unfortunately, the shape can change depending on the resolution one scans the parameters. On a macroscopic scale, the problem might look very non-convex with a lot of local minima, but close-ups around the optimal solutions could show a much more convex local environment.

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References

  • Achard P, De Schutter E (2006) Complex parameter landscape for a complex neuron model. PLoS Comput Biol 2:e94

    Article  PubMed Central  PubMed  Google Scholar 

  • Achard P, Van Geit W, LeMasson G (2010) Parameter Searching. In: De Schutter E (ed) Computational modeling methods for neuroscientists. MIT Press, Cambridge, pp 31–60

    Google Scholar 

  • Druckmann S, Banitt Y, Gidon A, Schürmann F, Markram H, Segev I (2007) A novel multiple objective optimization framework for constraining conductance-based neuron models by experimental data. Front Neurosci 1(1):7

    Article  PubMed Central  PubMed  Google Scholar 

  • Keren N, Bar-Yehuda D, Korngreen A (2009) Experimentally guided modelling of dendritic excitability in rat neocortical pyramidal neurones. J Physiol 587(7):1413–1437

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Maeda Y, Li Q (2007) Fuzzy adaptive search method for parallel genetic algorithm tuned by evolution degree based on diversity measure. In: Castillo et al (eds) Foundations of fuzzy logic and soft computing. Springer, Berlin/Heidelberg, pp 677–687

    Chapter  Google Scholar 

  • Mitra A, Manitius A, Sauer T (2013) A new technique to optimize single neuron models using experimental spike train data. In: American control conference (ACC), IEEE, Washington, DC, pp 346–351

    Google Scholar 

  • Nelder JA, Mead R (1965) A simplex method for function minimization. Comput J 7(4):308–313

    Article  Google Scholar 

  • Prinz AA, Billimoria CP, Marder E (2003) Alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons. J Neurophysiol 90:3998–4015

    Article  PubMed  Google Scholar 

  • Roth A, Bahl A (2009) Divide et impera: optimizing compartmental models of neurons step by step. J Physiol 587(7):1369–1370

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Vossou CG, Koukoulis IN, Provatidis CG (2007) Genetic combined with a simplex algorithm as an efficient method for the detection of a depressed ellipsoidal flaw using the boundary element method. Int J Appl Math Comput Sci 4(2):88–93

    Google Scholar 

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Correspondence to Werner Van Geit .

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Van Geit, W. (2014). Hybrid Parameter Optimization Methods. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_164-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_164-1

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  • Online ISBN: 978-1-4614-7320-6

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