Abstract
Following tissue injury, invading antigens are captured by dendritic cells (DC) which migrate to secondary lymphoid organs where they initiate immune responses that involve triads composed of T cells, B cells and DC. As both DC1 and B cells2 express functional CD40, we studied the effects of in vitro generated DC on B cells responses in a culture system where CD40-Ligand-transfected L cells are used as surrogate membranes of activated T cells.
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Fayette, J., Dubois, B., Caux, C., Banchereau, J., Brière, F. (1995). Human Dendritic Cells Can Drive CD40-Activated slgD+ B Cells to Mount Mucosal-Type Humoral Response. In: Banchereau, J., Schmitt, D. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 378. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1971-3_90
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DOI: https://doi.org/10.1007/978-1-4615-1971-3_90
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