Skip to main content

Widespread Tannin Intake Via Stimulants and Masticatories, Especially Guaraná, Kola Nut, Betel Vine, and Accessories

  • Chapter
Plant Polyphenols

Part of the book series: Basic Life Sciences ((BLSC,volume 59))

Abstract

Tannins are increasingly recognized as dietary carcinogens and as anti-nutrients interfering with the system’s full use of protein. Nevertheless, certain tannin-rich beverages, masticatories, and folk remedies, long utilized in African, Asiatic, Pacific, and Latin American countries, are now appearing in North American sundry shops and grocery stores. These include guarané (Paullinia cupana HBK.) from Brazil, kola nut (Colanitida Schott &, Endl. and C. acuminata Schott &, Endl.) from West Africa, and betel nut (Areca catechu L.) from Malaya. The betel nut, or arecanut, has long been associated with oral and esophageal cancer because of its tannin content and the tannin contributed by the highly astringent cutch from Acacia catechu L. and Uncaria gambir Roxb. and the aromatic, astringent ‘pan’ (leaves of Piper betle L.) chewed with it. In addition to the constant recreational/social ingestion of these plant materials, they are much consumed as aphrodisiacs and medications. Guarané and kola nut enjoy great popularity in their native lands because they are also rich in caffeine, which serves as a stimulant. Research and popular education on the deleterious effects of excessive tannin intake could do much to reduce the heavy burden of early mortality and health care, especially in developing countries.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Brody, J.E. Scientists seeking possible wonder drugs in tea. New York Times, Mar. 14, p. B8 (1991).

    Google Scholar 

  2. Morton, J.F. Search for carcinogenic principles. In: Swain, T.; Kleiman, R. (eds.). Recent advances in phytochemistry, Vol. 14. The resource potential in phytochemistry. Plenum Press, New York, (1980).

    Google Scholar 

  3. Cardoso, M. Cultivo do guaranazeiro. O Estaio de S. Paulo. Sept. 5, p. 15 (1976).

    Google Scholar 

  4. Higa, A. O planto do guaraná em Sao Paulo. O Estaio de S. Paulo. Feb. 15, p. 5 (1984).

    Google Scholar 

  5. deCastro, J.B. A cultura do guaranâ na Bahia. O Esiado de S. Paulo. Supl. Agric. 999, July 21, p. 8-10 (1974).

    Google Scholar 

  6. Schnee, L. Plantas comunes de Venezuela.3rd ed.Univ.Central de Venez., Fac.de Agron., Maracay (1984).

    Google Scholar 

  7. Steinmetz, E.F. Guaraná. Quart. J. Crude Drug Res. 6: 749 (1965).

    Google Scholar 

  8. Wren, R.C. (rev’d by E.M. Williamson and F.J. Evans). Potter’s new cyclopedia of botanical drugs and preparations. C.W. Daniel Co., Ltd., Saffron Waiden, England (1988).

    Google Scholar 

  9. Anonymous. Guaraná drink untested in U.S. Brazilian Bull. 23: 7 (1967).

    Google Scholar 

  10. Cheney, R.H. Beverages and your health. Reprinted from World Sci. Rev. Thanet Press, Margate, England, March, p. 1-6 (1956).

    Google Scholar 

  11. Torres, J. diP. Redescoberto o valor terapeutico do guaraná. O Estado dt S. Paulo. Supl. Agric. 1343, Apr. 15 (1981).

    Google Scholar 

  12. Paulina Guaraná Amazonas, Ltda. O Guaraná. Leaflet; 4 pp. Sao Paulo, S.P. Nov. (1981).

    Google Scholar 

  13. Sacramento, C.K. Guaraná: do plantio ao beneficiamento. J. Cacauicultor 115:6–7 (1983).

    Google Scholar 

  14. de Castro, J.B. O guaraná, uma cultura ainda indefinida.O Estado de S. Paulo.Supl. Agric. 907, October 15, p. 10 (1972).

    Google Scholar 

  15. Greenish, H.G. An introduction to the study of materia medica. J.amp;A. Churchill, London (1899).

    Google Scholar 

  16. Machado, O. Contribuicao ao estudo das plantas medicinais do Brasil-O guaraná.Rodriguesia 10: 89-110 + 13 Pis. (1946).

    Google Scholar 

  17. Cheney, R.H. The biology and economics of the beverage industry. Econ.Bot. 1(3): 243–275 (1947).

    Article  CAS  Google Scholar 

  18. Reed, M. Brazilian guaraná —tea money. Coin World, Jan. 14 (1976).

    Google Scholar 

  19. Anon. Guaraná: a misteriosa energia dos indios maués. Transe Mag. 2 (14): 12 (year not known).

    Google Scholar 

  20. Lima, M. Sem incentivo, Amazonas náo salva o guaraná. O Estado de S. Paulo. Dec. 21 (1975).

    Google Scholar 

  21. Greenwood, L. Californians to sample Brazilian mythology. Los Angeles Times. June 21 (1973).

    Google Scholar 

  22. Brown, C; Brown, R.; Brown, B. The South American cook book. Doubleday, Doranamp;Co., Inc., New York, NY (1939).

    Google Scholar 

  23. Anonymous. Brazilian beer and soft drink succeed in U.S. Braz. Bull. Jan. p. 6 (1977).

    Google Scholar 

  24. Erickson, H.T., Pinheiro, F., Correa, M., Escobar, J.R. Guaraná (Paullinia cupana) as a common crop in Brazilian Amazonia. Econ. Bot. 38: 273 (1984).

    Article  Google Scholar 

  25. Laboratorio Simōpes. Comprimidos de Guaraná de Amazonia. W.A. Simōes, Simōesamp;Cia. Ltda., Rio de Janeiro, Brazil.

    Google Scholar 

  26. Passe, L.M. Street talk. Street Pharmacologist 3: 2 (1980).

    Google Scholar 

  27. Benson, Pastor John, Sao Simao, S.P., Brazil. Pers. comm. July 14, 1984; Nov. 13, 1988.

    Google Scholar 

  28. Zaidman, Rev. N. Orange Park, FL 32073. Pers. comm. Aug. 1, 1990.

    Google Scholar 

  29. Van Eijnatten, C.L.M. Kola: its botany and cultivation. Comm. 59. Koninklijk Inst. voor de Tropen, Dept. Agr. Res., Amsterdam, Neth. (1969).

    Google Scholar 

  30. Little, E.L.; Woodbury, R.O.; Wadsworth, F.H. Trees of Puerto Rico and the Virgin Islands. Vol. 2. Agr. Handb. 449. U.S. Dept. Agr., For. Service, Washington, D.C. (1974).

    Google Scholar 

  31. Oladokun, A.O. Germination studies on Cola acuminata (P. Beauv.) Schott and Endlicher. Turrialba 35 (2): 109–115 (1985).

    Google Scholar 

  32. Sturtevant, E.L. (ed. by U.P. Hedrick). Notes on edible plants. New York Agr. Exper. Sta., Geneva, New York (1919).

    Google Scholar 

  33. Irvine, F.R. Woody plants of Ghana, with special reference to their uses. Oxford Univ. Press, London (1961).

    Google Scholar 

  34. Ogutuga, D.B.A. Chemical composition and potential commercial uses of kola nut, Cola nitida. Vent. (Schott and Endlicher). Ghana J. Agr. Sci. 8: 2 (121-125) (1975).

    Google Scholar 

  35. Nzekwu, O. Kola nut. Nigeria Mag. 71: 298–305 (1961).

    Google Scholar 

  36. Trease, G.E. and Evans, W.C. Pharmacognosy. 10th ed.The Williams & Wilkins Co., Baltimore, (1972).

    Google Scholar 

  37. Eka, O.U. Chemical composition and uses of kolanuts. J. West Afr. Sci. Assn. 16: 167–169 (1971).

    Google Scholar 

  38. Oludemokun, A.A.; McDonald, D. Effects of temperature and relative humidity on mold deterioration of stored kolanuts, Cola nitida. PL Dis. Rep. 60(12): 1008–1010 (1976).

    Google Scholar 

  39. Arctander, S. Perfume and flavor materials of natural origin. Steffen Arctander, Elizabeth, NJ (1966).

    Google Scholar 

  40. Godfrey-Sam-Aagrey, W. Cola production in Ghana. World Crops. 21(3): 196–199 (1969).

    Google Scholar 

  41. Ayensu, E.S. Medicinal plants of West Africa. Refer. Pub. Inc., Albonac, MI 48001.

    Google Scholar 

  42. Grieve, M. A modern herbal. Hafner Pub. Co., New York and London (1967).

    Google Scholar 

  43. Heath, H.B. Flavor technology, profiles, products, applications. AVI Pub. Co., Inc., Westport, CT (1978).

    Google Scholar 

  44. Furia, T.E.; Bellanca, N. Fenaroli’s handbook of flavor ingredients. Chem. Rubber Co., Cleveland, OH (1971).

    Google Scholar 

  45. Howes, E.N. Nuts:their production and everyday uses. Faber & Faber, Ltd., London (1953).

    Google Scholar 

  46. Tyler, V.E., Brady, L.R.; Robbers, J.E. Pharmacognosy. 9th ed. Lea & Febiger, Philadelphia (1988).

    Google Scholar 

  47. Osei, J.E. Cola nitida trees and the early field performance of their budlings. Legon Agr. Res. Bull. (Ghana) 2: 62–65 (1987).

    Google Scholar 

  48. Young, L.A.; Young, L.G.; Klein, M.M.; Klein, D.M.; Beyer, D. Recreational drugs. Macmillan Pub. Co., Inc., New York, (1985).

    Google Scholar 

  49. Anonymous. The wealth of India: raw materials. Vol. I., Rev’d. Pub. and Info. Dir., Coun. Sci. and Indus. Res., New Delhi (1985).

    Google Scholar 

  50. Quisumbing, E. Medicinal plants of the Philippines. Tech. Bull. 16. Philippines Departs ment of Agriculture and Natural Resources, Manila (1951).

    Google Scholar 

  51. Raghavan, V.; Baruah, H.N. Arecanut: India’s popular masticatory—history, chemistry and utilization. Econ. Bot 12(4): 315–345 (1958).

    Article  Google Scholar 

  52. Petelot, A. Plantes medicinales du Cambodge, du Laos et du Vietnam. Centre de Rech. Sci. et Tech., Arch, des Rech. Agron. au Camb., au Laos, et au Viet., Saigon (1954).

    Google Scholar 

  53. Safford, W.E. Useful plants of the Island of Guam. Smithsonian Inst., U.S. Nat’s. Mus., Washington, D.C. (1905).

    Google Scholar 

  54. Govindarajan, V.S. Technological research in arecanut. Indian Farming 18(4):26–27 (1968).

    Google Scholar 

  55. Bavappa, K.V.A. Arecanut research and development — a success story. Indian Farming 32(9): 3–5 (1982).

    Google Scholar 

  56. Watt. G. The commercial products of India. John Murray, London (1908).

    Google Scholar 

  57. Benthall, A.P. Trees of Calcutta and its neighborhood. Thacker Spink & Co. (1933) Ltd., Calcutta (1946).

    Google Scholar 

  58. Patil, R.T. Drying studies on arecanut (A. catechu Linn.). J. Fd.Sci.Technol. 26(2): 106–109 (1989).

    Google Scholar 

  59. Nambiar, K.K.N.; Radhakrish Nair, R. Spoilage of processed arecanuts. Arecanutamp;Spices 2 (1): 8-10 91970).

    Google Scholar 

  60. Chempakam, B.; Annamalai, S.J.K.; Murthy, K.N. Other uses of arecanut. Indian Farming 32(9): 40–43 (1982).

    Google Scholar 

  61. Mujumdar, A.M.; Kapadi, A.H.; Pendse, G.S. Chemistry and pharmacology of betel nut (Areca catechu Linn.). J. Plantation Crops 7(2): 69–92 (1979).

    CAS  Google Scholar 

  62. Lalithakumari, H.; Sirsi, M.; and Govindarajan, V.S. Antibacterial and antifungal activities of Areca catechu Linn. Indian J. Exp. Biol. 3: 66–67 (1965).

    PubMed  CAS  Google Scholar 

  63. Chopra, R.N.; Chopra, I.C.; Handa, K.L.; Kapur, L.D. Chopra’ indigenous drugs of India. 2nd ed. U.N. Dhuramp;Sons, Private, Ltd., Calcutta, India (1958).

    Google Scholar 

  64. Senewiratne, B. Betel chewing in Ceylon. Amer.J. Trop.Med.Hyg. 22(3): 418–422 (1973).

    CAS  Google Scholar 

  65. Shirname, L.P.; Menon, M.M.; Bhide, S.V. Mutagenicity of betel quid and its ingredients, using mammalian test systems. Carcinogenesis 5(4): 501–503 (1984).

    Article  PubMed  CAS  Google Scholar 

  66. Nair, J.; Nair, U.J.; Ohshima, H.; Bhide, S.V.; Bartsch, H. Endogenous nitrosation in the oral cavity of chewers while chewing betel quid with or without tobacco. In: Bartsch, H.; Schulte-Hermann, A.; O’Neill, I.K. (eds). Relevance of N-nitroso compounds to human cancer: exposure and mechanisms. (Proc. 9th Internat. Symp. on N-Nitroso Compounds). Pub. 84. Internat. Agency for Res. on Cancer, Lyon, France (1987).

    Google Scholar 

  67. Sen, S.; Talukder, G.; Sharma, A. Potentiation of betel-induced alterations of mouse glandular stomach mucosa by tobacco in studies simulating betel addiction. Int. J. Crude Drug Res. 25(4): 209–215 (1987).

    Google Scholar 

  68. Stitch, H.F.; Ohshima, H.; Pignatelli, B.; Michelson, J.; Bartsch, J. Inhibitory effect of betel nut extracts on endogenous nitrosation in humans.J. Nat.Cancer Inst.70 (6): 1047-1050.

    Google Scholar 

  69. Wenke, G.; Hoffmann, D. A study of betel quid carcinogenesis.I. On the in vitro N-nitrosation of arecolene. Carcinogenesis 4(2): 169–172 (1983).

    Article  PubMed  CAS  Google Scholar 

  70. Chin, CT.; Lee, K.W. The effects of betel-nut chewing on the buccal mucosa of 296 Indians and Malays in West Malaysia: a clinical study. Brit. J. Cancer 24(3): 427–432 (1970).

    Article  PubMed  CAS  Google Scholar 

  71. Sen, S.; Tallukder, G.; Sharma, A. Sequential histologic alterations of mouse gastric mucosa following long-term simulation of betel addiction. Int. J. Crude Drug Res., 28(1): 5–16 (1989).

    Google Scholar 

  72. Morton, J.F. Plant tannins and esophageal cancer. In: Deichmann, W.B. (ed.). Toxicology and occupational medicine.(Proc.10th Internat.Conf.).Elsevier North Holland, Inc. (1979).

    Google Scholar 

  73. Kapadia, J.G.; Chung, E.G.; Ghosh, B.; Shukla, Y.N.; Basak, S.P.; Morton, J.F.; Pradham, S.N. Carcinogenicity of some folk medicinal herbs in rats. J. Nat.Cancer Inst. 60(3): 683–686 (1978).

    PubMed  CAS  Google Scholar 

  74. Ranadive, K.J.; Ranadive, S.N.; Shivapurkar, N.M.; and Gothoskar, S.V. Betelquid chewing and oral cancer: experimental studies on hamsters. Int. J. Cancer 24(6): 835–843 (1979).

    Article  PubMed  CAS  Google Scholar 

  75. Rosin, M.P. The influence of pH on the convertogenic activity of plant phenolics. Mutation Res. 135: 109–113 (1984).

    Article  PubMed  CAS  Google Scholar 

  76. Gothoskar, S.V.; Pai, S.R. A study on parotid gland tumor induced in Swiss mice by tannin-containing fraction of betelnut. Indian J. Exp. Biol. 24: 229–231 (1986).

    PubMed  CAS  Google Scholar 

  77. Lakshmanachar, M.S. Recent trends in arecanut imports. Agr. Situation in India 19 (12): 1093-1099 91965).

    Google Scholar 

  78. Bhat, A.S.; Nayar, N.M. Maximise income from arecanut gardens. Indian Farming 25(11): 27–28 (1976).

    Google Scholar 

  79. Rawat, A.K.S.; Balasubrahmanyan, V.R. Betelvine cultivars need to be classified. Indian Hori. 32(4): 4–6 (1988).

    Google Scholar 

  80. Anonymous. Wealth of India: raw materials. Vol. 8. Pub. and Info. Dir., CSIR, New Delhi (1969).

    Google Scholar 

  81. Debnath, P.K.; Sengupta, K.; Sengupta, C; Chatterjee, B.N. Betelvine cultivation in West Bengal. Indian Farming 35(6): 22–23 (1985).

    Google Scholar 

  82. Rao, M.V. Growing betelvine in Madhya Pradesh. Indian Farming 18(92): 24–26 (1968).

    Google Scholar 

  83. Balasubrahmanyam, V.R.; Rawat, A.K.S. Betelvine (Piper betle L., Piperaceae). Econ. Bot. 44(4): 540–543 (1990).

    Google Scholar 

  84. Burkill, I.H. Dictionary of the economic products of the Malay Peninsula. Crown Agents for the Colonies, London, England (1935).

    Google Scholar 

  85. Rao, A.R. Modifying influences of betel quid ingredients on B(A)P-induced carcinogenesis in the buccal pounch of hamsters. Internat. J. Cancer 33(5): 581–586(1984).

    Article  CAS  Google Scholar 

  86. Diwakar, M.C.; Kulshrestha, S.P. Common diseases of pan (betelvine) in India and their control. Pesticides 20 (9): 35-36.

    Google Scholar 

  87. Battacharya, A.; Chowdhury, A.; Das, A.K.; Dasgupta, B.; Sengupta, K. Studies on the Foltap residue in betelvine leaves. Trop. Pest Manag. 34(2): 154–155 (1988).

    Article  Google Scholar 

  88. Pattnaik, M.R.; Senapati, A.K.; Pal, A.K.; Acharya, A. Persistence of Carbofuran in betel vine. Indian J. Hort. 46(1): 119–121.

    Google Scholar 

  89. Backer, C.A.; Bakhuizen van den Brink, Jr. Flora of Java. N.V.P. Noordhoff, Groningen, The Netherlands 91963).

    Google Scholar 

  90. Simmonds, P.L. The commercial product of the vegetable kingdom. T.F.A. Day, London (1854).

    Google Scholar 

  91. Anonymous. Wealth of India: raw materials. Vol. 10. Pub. and Info. Dir., CSIR, New Delhi, India (1976).

    Google Scholar 

  92. Budavari, S. (ed.); O’Neill, M.J. (assoc. ed.); Smith, A. (asst. ed.). The Merck index. 11th ed. Merck & Co., Rahway, NJ (1989).

    Google Scholar 

  93. King, J. American eclectic dispensatory.Moore, Wilstach, Keys & Co., Cincinnati, OH (1855).

    Google Scholar 

  94. Dastur, J.F. Useful plants of India and Pakistan. 2nd ed. D.B. Taraporevala Sons & Co., Ltd., Bombay, India (1951).

    Google Scholar 

  95. Drury, H. The useful plants of India. 2nd ed. William H. Allen & Co., London, England (1873).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer Science+Business Media New York

About this chapter

Cite this chapter

Morton, J.F. (1992). Widespread Tannin Intake Via Stimulants and Masticatories, Especially Guaraná, Kola Nut, Betel Vine, and Accessories. In: Hemingway, R.W., Laks, P.E. (eds) Plant Polyphenols. Basic Life Sciences, vol 59. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3476-1_45

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-3476-1_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6540-2

  • Online ISBN: 978-1-4615-3476-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics