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Recent Advances in Development of a Rotavirus Vaccine for Prevention of Severe Diarrheal Illness of Infants and Young Children

  • Chapter
Immunology of Milk and the Neonate

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 310))

Abstract

Diarrheal diseases are an important cause of morbidity in infants and young children in developed countries and a major cause of both morbidity and mortality in this same age group in developing countriesl. The toll from diarrheal diseases in the developing countries is enormous. For example, it is estimated that in Asia, Africa, and Latin America, 3–5 billion cases of diarrhea and 5–10 million diarrhea-associated deaths occur each year2. In addition, diarrhea was ranked first among infectious diseases with regard to the number of episodes and the number of deaths in these areas of the world.

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Author information

Authors and Affiliations

  1. National Institutes of Health, Bethesda, MD, USA

    Albert Z. Kapikian, Jorge Flores, Kim Y. Green, Mario Gorziglia, Yasutaka Hoshino & Robert M. Chanock

  2. University of Tampere, Tampere, Finland

    Timo Vesikari & Tarja Ruuska

  3. University of Rochester, Rochester, NY, USA

    H. Paul Madore

  4. Johns Hopkins University, Baltimore, MD, USA

    Karen Midthun

  5. Central University of Venezuela, Caracas, Venezuela

    Irene Perez-Schael

Authors
  1. Albert Z. Kapikian
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  2. Jorge Flores
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  3. Timo Vesikari
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  4. Tarja Ruuska
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  5. H. Paul Madore
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  6. Kim Y. Green
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  7. Mario Gorziglia
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  8. Yasutaka Hoshino
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  9. Robert M. Chanock
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Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky

  2. National Institutes of Health, Bethesda, Maryland, USA

    Claudia Blair

  3. University of Texas, Galveston, Texas, USA

    Pearay L. Ogra

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© 1991 Springer Science+Business Media New York

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Kapikian, A.Z. et al. (1991). Recent Advances in Development of a Rotavirus Vaccine for Prevention of Severe Diarrheal Illness of Infants and Young Children. In: Mestecky, J., Blair, C., Ogra, P.L. (eds) Immunology of Milk and the Neonate. Advances in Experimental Medicine and Biology, vol 310. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3838-7_34

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  • DOI: https://doi.org/10.1007/978-1-4615-3838-7_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6713-0

  • Online ISBN: 978-1-4615-3838-7

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