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Host Proteins in the Replication of Bacteriophage RNA

  • Chapter
Gene Expression and its Regulation

Part of the book series: Basic Life Sciences ((BLSC))

Abstract

In recent years, the bacteriophage Qβ RNA polymerase reaction has become a highly characterized system for studying the synthesis of genetic material. An outstanding feature of this reaction is the actual replication of infectious bacteriophage RNA, as first shown by Spiegelman et al. (1). All of the reaction components have now been isolated as discrete species:

  1. (a)

    The enzyme, containing four proteins.

  2. (b)

    A host RNA binding factor, composed of a single protein.

  3. (c)

    A basic protein factor, of which there are many active species.

  4. (d)

    Qβ RNA.

  5. (e)

    Q β RNA complementary strand.

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Author information

Authors and Affiliations

  1. Department of Molecular Biology, Division of Biological Sciences, Albert Einstein College of Medicine, Bronx, New York, USA

    J. T. August, Lillian Eoyang, M. T. Franze de Fernández, W. S. Hayward, C. H. Kuo & P. M. Silverman

Authors
  1. J. T. August
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  2. Lillian Eoyang
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  3. M. T. Franze de Fernández
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  4. W. S. Hayward
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  5. C. H. Kuo
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  6. P. M. Silverman
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Editor information

Editors and Affiliations

  1. Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

    Francis T. Kenney  & Barbara A. Hamkalo  & 

  2. Departamento de Bioquimica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

    Gabriel Favelukes (General Secretary of the Symposium) (General Secretary of the Symposium)

  3. Department of Molecular Biology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA

    J. Thomas August

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© 1973 Plenum Press, New York

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August, J.T., Eoyang, L., Franze de Fernández, M.T., Hayward, W.S., Kuo, C.H., Silverman, P.M. (1973). Host Proteins in the Replication of Bacteriophage RNA. In: Kenney, F.T., Hamkalo, B.A., Favelukes, G., August, J.T. (eds) Gene Expression and its Regulation. Basic Life Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0877-5_3

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  • DOI: https://doi.org/10.1007/978-1-4684-0877-5_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0879-9

  • Online ISBN: 978-1-4684-0877-5

  • eBook Packages: Springer Book Archive

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