Abstract
The vascular pattern of hypovolemia with diminished cardiac output in the early stages of shock syndromes is well recognized and has been extensively studied by many investigators. However, with the development of techniques for rapid performing hemodynamic and respiratory measurements at the bedside, a new range of altered physiologic responses in shock syndromes has been observed. These recently recognized circulatory patterns consist of a hyperkinetic circulation with high cardiac output and rapid mean circulation time in the presence of arterial hypotension and progressive clinical deterioration (Mac — Lean et al. 1965; Khe and Shoemaker 1968; Duff et al. 1969).
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Border, J. R., Gallo, E., Schenk, W. G. (1966): Systemic arteriovenous shunts in patients under severe stress: a common cause of cardiac high output failure? Surgery 60, 225.
Clowes, G. H. et al (1966): The cardiac output in septic shock. Annals of Surgery, 163, 866.
Cohn, J. D., Greenspan, M., Golstein, C. R., Gudwin, A. L., Siegel, J. H., Del Guercio, L. R. M. (1968): Arteriovenous shunting in high cardiac output shock syndromes. Surgery, Gynecology, & Obstetrics, 127, 282.
Desai, J. M., Kim, S. I., Shoemaker, W. C. (1969): Sequential hemodynamic changes in an experimental hemorrhage shock preparation designed to simulate clinical shock. Annals of Surgery, 170, 157.
Duff, J. H., Groves, A.C., MacLean, A. P., La Pointe, R., MacLean, L. D. (1969): Defective oxygen consumption in septic shock. Surgery, Gynecology & Obstetrics, 128, 1051.
Hopkins, R. W., Sabga, G., Penn, I., Simeone, F. A. (1965); Hemodynamic aspects of hemorrhagic and septic shock. J. A. M. A., 191, 731.
Kho, L. K., Shoemaker, W. C. (1968): Evaluation of therapy in clinical shock by cardiorespiratory measurements. Surgery Gynecology, & Obstetrics 127, 81.
MacLean, L. D., Duff, J. H., Scott, H. M., Peretz, D.I. (1965): Treatment of shock in man based on hemodynamic diagnosis. Surgery, Gynecology, & Obstetrics 120, 1.
Poivert, M. et al. (1966): Journal de Chirurgie 92, 131.
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© 1970 Plenum Press, New York
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Gallone, L. (1970). Problems of Clinical Research in Shock. In: Bertelli, A., Back, N. (eds) Shock: Biochemical, Pharmacological, and Clinical Aspects. Advances in Experimental Medicine and Biology, vol 9. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3201-5_19
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DOI: https://doi.org/10.1007/978-1-4684-3201-5_19
Publisher Name: Springer, Boston, MA
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