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Mechanisms of Transdifferentiation of Pigment Epithelial Cells into Neural Retina: A Hypothesis

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Recent Trends in Regeneration Research

Part of the book series: NATO ASI Series ((NSSA,volume 172))

Abstract

The adult amphibian eye is a very convenient model for studying the events involved in the process that has been called transdifferentiation. In this system, which involves regeneration of the lens and/or retina in the adult newt or certain other amphibia, fully differentiated cells of adult somatic tissue are released from the control of the differentiated state and are channeled into a new pathway of cell type differentiation.

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References

  • Stroeva, O.G., and Mitashov, V.I., 1983, Retinal pigment epithelium: Proliferation and differentiation during development and regeneration, Int. Rev. Cytol., 83:221–293.

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© 1989 Plenum Press, New York

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Mitashov, V. (1989). Mechanisms of Transdifferentiation of Pigment Epithelial Cells into Neural Retina: A Hypothesis. In: Kiortsis, V., Koussoulakos, S., Wallace, H. (eds) Recent Trends in Regeneration Research. NATO ASI Series, vol 172. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9057-2_28

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  • DOI: https://doi.org/10.1007/978-1-4684-9057-2_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-9059-6

  • Online ISBN: 978-1-4684-9057-2

  • eBook Packages: Springer Book Archive

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